Global Threshold Dynamics of an Infection Age-Space Structured HIV Infection Model with Neumann Boundary Condition

Author(s):  
Jinliang Wang ◽  
Ran Zhang ◽  
Yue Gao
2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Zhimin Chen ◽  
Xiuxiang Liu ◽  
Liling Zeng

Abstract In this paper, a human immunodeficiency virus (HIV) infection model that includes a protease inhibitor (PI), two intracellular delays, and a general incidence function is derived from biologically natural assumptions. The global dynamical behavior of the model in terms of the basic reproduction number $\mathcal{R}_{0}$ R 0 is investigated by the methods of Lyapunov functional and limiting system. The infection-free equilibrium is globally asymptotically stable if $\mathcal{R}_{0}\leq 1$ R 0 ≤ 1 . If $\mathcal{R}_{0}>1$ R 0 > 1 , then the positive equilibrium is globally asymptotically stable. Finally, numerical simulations are performed to illustrate the main results and to analyze thre effects of time delays and the efficacy of the PI on $\mathcal{R}_{0}$ R 0 .


2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Agil K. Khanmamedov ◽  
Nigar F. Gafarova

AbstractAn anharmonic oscillator {T(q)=-\frac{d^{2}}{dx^{2}}+x^{2}+q(x)} on the half-axis {0\leq x<\infty} with the Neumann boundary condition is considered. By means of transformation operators, the direct and inverse spectral problems are studied. We obtain the main integral equations of the inverse problem and prove that the main equation is uniquely solvable. An effective algorithm for reconstruction of perturbed potential is indicated.


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