Hopf bifurcation analysis in a stage-structure predator–prey model with two time delay

In this paper, we consider a predator-prey system with two time delays, which describes a prey–predator model with parental care for predators. The local stability of the positive equilibrium is analysed. By choosing the two time delays as the bifurcation parameter, the existence of Hopf bifurcation is studied. Numerical simulations show the positive equilibrium loses its stability via the Hopf bifurcation when the time delay increases beyond a threshold.

Evaluation of the Number of Visits to Chinese Medical Institutions Using a Logistic Differential Equation Model

In this study, we established a two-dimensional logistic differential equation model to study the number of visits in Chinese PHCIs and hospitals based on the behavior of patients. We determine the model's equilibrium points and analyze their stability and then use China medical services data to fit the unknown parameters of the model. Finally, the sensitivity of model parameters is evaluated to determine the parameters that are susceptible to influence the system. The results indicate that the system corresponds to the zero-equilibrium point, the boundary equilibrium point, and the positive equilibrium point under different parameter conditions. We found that, in order to substantially increase visits to PHCIs, efforts should be made to improve PHCI comprehensive capacity and maximum service capacity.

The Impact of Government Spending on Economic Diversification for the Period (2004-2019) and its Reflection on the Path of Rehabilitation of the Iraqi Economy

The research aims to measure and analyze the relationship between government spending and economic diversification in Iraq for the period (2004-2019), using the ARDL model. The research concluded that there is a long-term positive equilibrium relationship between investment spending and economic diversification in Iraq. When investment spending increases by (1%), this will lead to an increase in economic diversification by (0.23%), assuming that operating spending is stable, and the opposite happens in the case of decline. In addition to the existence of a long-term inverse equilibrium relationship between operating spending and economic diversification in Iraq, as an increase in operating spending by (1%) will lead to a decrease in economic diversification by (0.73%), assuming the stability of investment spending, and the opposite will happen in the event of decline.

Global attractivity for a nonautonomous Nicholson’s equation with mixed monotonicities

We consider a Nicholson’s equation with multiple pairs of time-varying delays and nonlinear terms given by mixed monotone functions. Sufficient conditions for the permanence, local stability and global attractivity of its positive equilibrium K are established. The main novelty here is the construction of a suitable auxiliary difference equation x n+1 = h(x n ) with h having negative Schwarzian derivative, and its application to derive the attractivity of K for a model with one or more pairs of time-dependent delays. Our criteria depend on the size of some delays, improve results in recent literature and provide answers to open problems.

Dynamic Analysis in a Plankton Ecosystem Involving Two Delays

In this paper, a phytoplankton and zooplankton relationship system with two delays is investigated whose coefficients are related to one of the two delays. Firstly, the dynamic behaviors of the system with one delay are given and the stability of positive equilibrium and the existence of periodic solutions are obtained. Using the fact that the system may occur, the stable switching phenomenon is verified. Under certain conditions, the periodic solutions will exist in a wide range as the delay gets away from critical values. Fixing the delay [Formula: see text] in the stable interval, it is revealed that the effect of [Formula: see text] can also cause the vibration of system. This explains that two delays play an important role in the oscillation behavior of the system. Furthermore, using the crossing curve methods, the stable changes of the positive equilibrium in two-delays plane are given, which generalizes the results of systems for which the coefficients do not depend on delay. Some numerical simulations are provided to verify the theoretical results.

Multiple Time Delays Induced Dynamics of p53 Gene Regulatory Network

p53 dynamics plays an important role in determining cell arrest or apoptosis upon DNA damage response. In this paper, based on a p53 gene regulatory network composed of its core regulator ATM, Mdm2 and Wip1, the effect of multiple time delays in transcription and translation of Mdm2 and Wip1 gene expression on p53 dynamics are investigated through theoretical and numerical analyses. The stability of the positive equilibrium point and the existence of Hopf bifurcation are demonstrated through analyzing the associated characteristic equation of the corresponding linearized system in five cases. Detailed numerical simulations and bifurcation analyses are performed to support the theoretical results. The results show that with the increase of a time delay, the positive equilibrium point becomes unstable, and the p53 dynamics presents an oscillating state. These results reveal that time delay has a significant impact on p53 dynamics and may provide a useful insight into developing anti-cancer therapy.

Global Analysis of a Time Fractional Order Spatio-Temporal SIR Model

We deal in this paper with a diffusive SIR epidemic model described by reaction-diffusion equations involving a fractional derivative. The existence and uniqueness of the solution are shown, next to the boundedness of the solution. Further, it has been shown that the global behavior of the solution is governed by the value of R0 , which is known in epidemiology by the basic reproduction number. Indeed, using the Lyapunov direct method it has been proved that the disease will extinct for R0 < 1 for any value of the diffusion constants. For R0 > 1, the disease will persist and the unique positive equilibrium is globally stable. Some numerical illustrations have been used to confirm our theoretical results.Subject classification: 26A33; 34A08; 92D30; 35K57.

The Neimark–Sacker Bifurcation and Global Stability of Perturbation of Sigmoid Beverton–Holt Difference Equation

We present the bifurcation results for the difference equation x n + 1 = x n 2 / a x n 2 + x n − 1 2 + f where a and f are positive numbers and the initial conditions x − 1 and x 0 are nonnegative numbers. This difference equation is one of the perturbations of the sigmoid Beverton–Holt difference equation, which is a major mathematical model in population dynamics. We will show that this difference equation exhibits transcritical and Neimark–Sacker bifurcations but not flip (period-doubling) bifurcation since this difference equation cannot have period-two solutions. Furthermore, we give the asymptotic approximation of the invariant manifolds, stable, unstable, and center manifolds of the equilibrium solutions. We give the necessary and sufficient conditions for global asymptotic stability of the zero equilibrium as well as sufficient conditions for global asymptotic stability of the positive equilibrium.

Global Stability Analysis of a Five-Dimensional Unemployment Model with Distributed Delay

The present paper proposes a five-dimensional mathematical model for studying the labor market, focusing on unemployment, migration, fixed term contractors, full time employment and the number of available vacancies. The distributed time delay is considered in the rate of change of available vacancies that depends on the past regular employment levels. The non-dimensional mathematical model is introduced and the existence of the equilibrium points is analyzed. The positivity and boundedness of solutions are provided and global asymptotic stability findings are presented both for the employment free equilibrium and the positive equilibrium. The numerical simulations support the theoretical results.