Effects of recombinant human intestinal trefoil factor on trinitrobenzene sulphonic acid induced colitis in rats

2010 ◽  
Vol 38 (7) ◽  
pp. 4787-4792 ◽  
Author(s):  
Jin Li ◽  
Rui Zhou ◽  
Wen-cheng He ◽  
Bing Xia
1995 ◽  
Vol 311 (1) ◽  
pp. 293-297 ◽  
Author(s):  
M Tomita ◽  
H Itoh ◽  
N Ishikawa ◽  
A Higa ◽  
H Ide ◽  
...  

A cDNA encoding mouse intestinal trefoil factor (mITF) was successfully cloned and sequenced from the small intestine of C57BL/6 mouse by using the combination of reverse transcription-PCR and rapid amplification of cDNA ends methods. The gene was, similar to rat and human ITFs, mainly expressed in the small and large intestine. The mITF expression was up-regulated during the recovery phase after depletion of goblet cells in acetic acid-induced colitis. On the other hand, the expression in the jejunum was not altered, while goblet cell hyperplasia was induced by Nippostrongylus brasiliensis infection. These results suggest that the mITF expression did not simply correlate with the number of goblet cells. The mITF may play an important role in the maintenance and repair of mucosal function of the rectum. Additionally, the mITF in the jejunum may play a role in alteration of the physicochemical nature of goblet cell mucins, thereby affecting the establishment of intestinal helminths.


2004 ◽  
Vol 39 (12) ◽  
pp. 1250-1258 ◽  
Author(s):  
F. Lamine ◽  
H. Eutamène ◽  
J. Fioramonti ◽  
L. Buéno ◽  
V. Théodorou

2002 ◽  
Vol 130 (3) ◽  
pp. 526-531 ◽  
Author(s):  
C. CIACCI ◽  
D. DI VIZIO ◽  
R. SETH ◽  
G. INSABATO ◽  
G. MAZZACCA ◽  
...  

2016 ◽  
Vol 46 ◽  
pp. 921-925 ◽  
Author(s):  
Xiaolian YI ◽  
Xiaojun CHANG ◽  
Jijie WANG ◽  
Caixia YAN ◽  
Binghong ZHANG

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e74669 ◽  
Author(s):  
Zhang Yong ◽  
Wang Lin ◽  
Sun Yong ◽  
Liang Guang-ping ◽  
Wu Dan ◽  
...  

2000 ◽  
Vol 118 (4) ◽  
pp. A36
Author(s):  
Gi-Shih Lien ◽  
Anatoly Leytin ◽  
Anli Chen ◽  
Noam Harpaz ◽  
Mark W. Babyatsky ◽  
...  

2020 ◽  
Vol 26 (48) ◽  
pp. 7619-7632
Author(s):  
Yun Huang ◽  
Meng-Meng Wang ◽  
Zhi-Zhou Yang ◽  
Yi Ren ◽  
Wei Zhang ◽  
...  

2008 ◽  
Vol 283 (19) ◽  
pp. 13418-13427 ◽  
Author(s):  
Friedrich P. Paulsen ◽  
Chee-Wai Woon ◽  
Deike Varoga ◽  
Anne Jansen ◽  
Fabian Garreis ◽  
...  

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