scholarly journals Evaluation of OIDx Histoplasma Urinary Antigen EIA

2021 ◽  
Author(s):  
Diego H. Cáceres ◽  
Beatriz L. Gómez ◽  
Ángela M. Tobón ◽  
Tom M. Chiller ◽  
Mark D. Lindsley
Keyword(s):  
Urinary Antigen

Legionella Urinary Antigen in Early Disease

1994 ◽  
Vol 26 (6) ◽  
pp. 777-778 ◽  
Author(s):  
Sverker Bernander ◽  
Bengt Gästrin ◽  
Sture Löfgren ◽  
Anne-Marie Olinder-Nielsen
Keyword(s):  
Urinary Antigen ◽  
Early Disease

scholarly journals Investigating the dynamics of Leishmania antigen in the urine of patients with visceral leishmaniasis: a pilot study

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1514
Author(s):  
Prakash Ghosh ◽  
Israel Cruz ◽  
Albert Picado ◽  
Thomas Edwards ◽  
Md. Anik Ashfaq Khan ◽  
...  
Keyword(s):  
Pilot Study ◽  
Visceral Leishmaniasis ◽  
Treatment Monitoring ◽  
Urine Samples ◽  
Urinary Antigen ◽  
Antigen Concentration ◽  
Elisa Kit ◽  
Time Points ◽  
Non Invasive ◽  
Antigen Elisa

Background: Detection of Leishmania antigens in the urine provides a non-invasive means of diagnosis and treatment monitoring of cases of visceral leishmaniasis (VL). Leishmania antigen load in the urine may vary between different time-points within a day, thus influencing the performance of antigen-detection tests. Methods: We investigated the dynamics of Leishmania antigen in urine collected at three different time points (08:00, 12:00 and 16:00 hours). All urine samples collected were tested with the Leishmania Antigen ELISA (VL ELISA) kit, produced by Kalon Biological Ltd., UK. Results: The median concentration of Leishmania antigen in urine collected at 08:00 (2.7 UAU-urinary antigen units/ml) was higher than at 12:00 (1.7 UAU/ml) and at 16:00 (1.9 UAU/ml). These differences were found to be statistically significant (08:00 vs. 12:00, p=0.011; 08:00 vs. 16:00, p=0.041). Conclusion: This pilot study indicates that the Leishmania antigen concentration is higher in urine samples collected in the morning, which has important implications when the VL ELISA kit or other tests to detect Leishmania antigen in urine are used for diagnosis of VL and treatment monitoring.

A novel use of pneumococcal urinary antigen detection kits to identify Streptococcus pneumoniae cultures misidentified by the VITEK-2 system

2019 ◽  
Vol 50 (2) ◽  
pp. 146-149
Author(s):  
Sadia Khan ◽  
Sona P Hydrose ◽  
Sabthami Chandran ◽  
Kavitha Dinesh ◽  
Anil Kumar
Keyword(s):  
Streptococcus Pneumoniae ◽  
Latex Agglutination ◽  
Urinary Antigen ◽  
Urinary Antigen Test ◽  
Middle Income ◽  
Microbial Identification ◽  
Middle Income Countries ◽  
Vitek 2 ◽  
Urinary Antigen Detection ◽  
Viridans Group Streptococci

Streptococcus pneumoniae infections continue to be an important cause of morbidity and mortality in low-and middle-income countries. Differentiating S. pneumoniae from viridans group streptococci is essential to ensure appropriate antibiotic therapy. Conventional microbial identification tests can often misidentify the two groups. We used a common pneumococcal urinary antigen test to identify S. pneumoniae that were misidentified by the VITEK 2. The performance of the test was similar to the pneumococcal latex agglutination test.

Urinary antigen tests and the investigation of suspected community acquired pneumonia

2019 ◽  
Vol 79 (4) ◽  
pp. 389-399
Author(s):  
Sakib Rokadiya ◽  
Poppy Denniston ◽  
William Ricketts ◽  
Jonathan Lambourne
Keyword(s):  
Community Acquired Pneumonia ◽  
Urinary Antigen ◽  
Antigen Tests

Utility of the Legionella urinary antigen

2019 ◽  
Vol 49 (8) ◽  
pp. 1050-1051
Author(s):  
Ian Gassiep ◽  
Mark Armstrong ◽  
Christopher S. Heather ◽  
Robert E. Norton
Keyword(s):  
Urinary Antigen

scholarly journals Multiplex Urinary Antigen Detection for 13 Streptococcus pneumoniae Serotypes Improves Diagnosis of Pneumococcal Pneumonia in South African HIV-Infected Adults

2016 ◽  
Vol 55 (1) ◽  
pp. 302-312 ◽  
Author(s):  
Werner C. Albrich ◽  
Michael W. Pride ◽  
Shabir A. Madhi ◽  
Jan Callahan ◽  
Peter V. Adrian ◽  
...  
Keyword(s):  
South African ◽  
Pneumococcal Pneumonia ◽  
Antigen Detection ◽  
Urinary Antigen ◽  
Content Type ◽  
Urinary Antigen Detection ◽  
Dominant Serotype ◽  
Quellung Reaction ◽  
Urine Specimens ◽  
Asymptomatic Hiv

ABSTRACT A serotype-specific urinary antigen detection (UAD) assay for 13 serotypes included in the pneumococcal conjugate vaccine (PCV13) was recently reported as a useful diagnostic tool for pneumococcal pneumonia. We aimed to assess the diagnostic accuracy of the UAD in HIV-infected South African adults. Urine specimens from a well-defined cohort of HIV-infected South African adults with pneumonia were evaluated retrospectively in the UAD assay. Pneumonia was considered pneumococcal if either sputum Gram stain, sputum culture, blood culture, or the immunochromatographic (ICT) BinaxNow S. pneumoniae test (composite diagnostic) was positive. Among 235 enrolled pneumonia patients, the UAD assay was more frequently positive (104 [44.3%]) than the composite diagnostic (71 [30.2%]; P < 0.001) and increased the pneumococcal etiology from 30.2% by an additional 22.6% to 52.8%. The UAD assay detected more pneumococcal etiologies (45.0%) than the serotype-independent ICT (23.4%, P < 0.001). UAD identified 6/7 patients with PCV13 serotype bacteremia without misclassification of bacteremia episodes due to non-PCV13 serotypes. UAD was positive for 5.1% of asymptomatic HIV-infected persons, with higher rates among those with nasopharyngeal carriage. Concordance between serotypes identified by UAD and by Quellung reaction and PCR serotyping was 70/86 (81.4%). UAD identified the dominant serotype in multiple serotype carriage. This study confirms the utility of the UAD assay for HIV-infected adults comparing favorably with other diagnostic tests. A highly valent UAD may become a new standard for detection of pneumococcal pneumonia in adults. Prior to PCV introduction, at least 53% of pneumonia cases were due to pneumococci in HIV-infected South African adults.

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