Local Hopf bifurcation analysis and global existence of periodic solutions in a gene expression model with delays

2016 ◽  
Vol 86 (1) ◽  
pp. 245-256 ◽  
Author(s):  
Jinchen Yu ◽  
Mingshu Peng
Keyword(s):  
Gene Expression ◽  
Hopf Bifurcation ◽  
Global Existence ◽  
Periodic Solutions ◽  
Bifurcation Analysis ◽  
Local Hopf Bifurcation ◽  
Expression Model ◽  
Existence Of Periodic Solutions ◽  
Gene Expression Model

Hopf bifurcation analysis in a model of oscillatory gene expression with delay

2009 ◽  
Vol 139 (4) ◽  
pp. 879-895 ◽  
Author(s):  
Junjie Wei ◽  
Chunbo Yu
Keyword(s):  
Gene Expression ◽  
Hopf Bifurcation ◽  
Periodic Solutions ◽  
Normal Forms ◽  
Higher Dimensional ◽  
Expression Model ◽  
Oscillatory Gene Expression ◽  
Existence Of Periodic Solutions ◽  
The Stability ◽  
Gene Expression Model

The dynamics of a gene expression model with time delay are investigated. The investigation confirms that a Hopf bifurcation occurs due to the existence of stability switches when the delay varies. An explicit algorithm for determining the direction of the Hopf bifurcations and the stability of the bifurcating periodic solutions has been derived by using the theory of the centre manifold and the normal forms method. The global existence of periodic solutions has been established using a global Hopf bifurcation result by Wu and a Bendixson criterion for higher-dimensional ordinary differential equations due to Li and Muldowney.

scholarly journals Global Existence of Periodic Solutions in a Delayed Kaldor-Kalecki Model

2009 ◽  
Vol 14 (4) ◽  
pp. 463-472 ◽  
Author(s):  
A. Kaddar ◽  
H. Talibi Alaoui
Keyword(s):  
Hopf Bifurcation ◽  
Global Existence ◽  
Business Cycle ◽  
Periodic Solutions ◽  
Cycle Model ◽  
Global Hopf Bifurcation ◽  
Numerical Examples ◽  
Existence Of Periodic Solutions ◽  
Business Cycle Model ◽  
Theoretical Results

This paper is concerned with a delayed Kaldor-Kalecki non-linear business cycle model in income. By applying a global Hopf bifurcation result due to Wu, the global existence of periodic solutions is investigated. Numerical examples will be given in the end, to illustrate our theoretical results.

scholarly journals Global existence of periodic solutions in a simplified four-neuron BAM neural network model with multiple delays

2006 ◽  
Vol 2006 ◽  
pp. 1-18 ◽  
Author(s):  
Xiang-Ping Yan ◽  
Wan-Tong Li
Keyword(s):  
Neural Network ◽  
Hopf Bifurcation ◽  
Global Existence ◽  
Periodic Solutions ◽  
Network Model ◽  
Neural Network Model ◽  
Multiple Delays ◽  
Global Hopf Bifurcation ◽  
Existence Of Periodic Solutions ◽  
Bam Neural Network

We consider a simplified bidirectional associated memory (BAM) neural network model with four neurons and multiple time delays. The global existence of periodic solutions bifurcating from Hopf bifurcations is investigated by applying the global Hopf bifurcation theorem due to Wu and Bendixson's criterion for high-dimensional ordinary differential equations due to Li and Muldowney. It is shown that the local Hopf bifurcation implies the global Hopf bifurcation after the second critical value of the sum of two delays. Numerical simulations supporting the theoretical analysis are also included.

GLOBAL EXISTENCE OF PERIODIC SOLUTIONS IN THE LINEARLY COUPLED MACKEY–GLASS SYSTEM

2011 ◽  
Vol 21 (03) ◽  
pp. 711-724 ◽  
Author(s):  
YANQIU LI ◽  
WEIHUA JIANG
Keyword(s):  
Hopf Bifurcation ◽  
Global Existence ◽  
Periodic Solutions ◽  
Center Manifold ◽  
Glass System ◽  
Positive Equilibrium ◽  
Higher Dimensional ◽  
Distribution Of Eigenvalues ◽  
Existence Of Periodic Solutions ◽  
The Stability

The dynamics of a linearly coupled Mackey–Glass system with delay are investigated. Based on the distribution of eigenvalues, we prove that a sequence of Hopf bifurcation occurs at the positive equilibrium as the delay increases and obtain the bifurcation set in the parameter plane. The explicit algorithm for determining the direction of Hopf bifurcation and the stability of the bifurcating periodic solutions are derived, using the theories of normal form and center manifold. The global existence of periodic solutions is established using a global Hopf bifurcation result due to Wu [1998] and a Bendixson's criterion for higher dimensional ordinary differential equations due to [Li & Muldowney, 1993].

scholarly journals Stability and Hopf Bifurcation Analysis of a Gene Expression Model with Diffusion and Time Delay

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Yahong Peng ◽  
Tonghua Zhang
Keyword(s):  
Gene Expression ◽  
Hopf Bifurcation ◽  
Local Stability ◽  
Time Delays ◽  
Center Manifold ◽  
Hopf Bifurcations ◽  
Expression Model ◽  
The Stability ◽  
And Diffusion ◽  
Gene Expression Model

We consider a model for gene expression with one or two time delays and diffusion. The local stability and delay-induced Hopf bifurcation are investigated. We also derive the formulas determining the direction and the stability of Hopf bifurcations by calculating the normal form on the center manifold.

A NONLINEAR DELAY MODEL DESCRIBING THE GROWTH OF TUMOR CELLS UNDER IMMUNE SURVEILLANCE AGAINST CANCER AND ITS STABILITY ANALYSIS

2012 ◽  
Vol 05 (03) ◽  
pp. 1260017 ◽  
Author(s):  
LING CHEN ◽  
WANBIAO MA
Keyword(s):  
Stability Analysis ◽  
Hopf Bifurcation ◽  
Periodic Solutions ◽  
Tumor Cells ◽  
Local Stability ◽  
Immune Surveillance ◽  
Delay Model ◽  
Existence Of Periodic Solutions ◽  
Growth Of Tumor ◽  
Nonlinear Delay

In this paper, based on some biological meanings and a model which was proposed by Lefever and Garay (1978), a nonlinear delay model describing the growth of tumor cells under immune surveillance against cancer is given. Then, boundedness of the solutions, local stability of the equilibria and Hopf bifurcation of the model are discussed in details. The existence of periodic solutions explains the restrictive interactions between immune surveillance and the growth of the tumor cells.

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