Long-term follow-up for ectopic ACTH-secreting pituitary adenoma in a single tertiary medical center and a literature review

Object There are no published long-term data for patients with penetrating head injury treated with bilateral supratentorial craniectomy, or supra- and infratentorial craniectomy. The authors report their experience with 33 patients treated with bilateral or bicompartmental craniectomy from the ongoing conflicts in Iraq and Afghanistan. Methods An exploratory analysis of Glasgow Outcome Scale (GOS) scores at 6 months in 33 patients was performed. Follow-up lasting a median of more than 2 years was performed in 30 (91%) of these patients. The association of GOS score with categorical variables was explored using the Wilcoxon rank-sum test or Kruskal-Wallis analysis of variance. The Spearman correlation coefficient was used for ordinal/continuous data. To provide a clinically meaningful format to present GOS scores with categorical variables, patients with GOS scores of 1–3 were categorized as having a poor outcome and those with scores of 4 and 5 as having a good outcome. This analysis does not include the patients who died in theater or in Germany who underwent bilateral decompressive craniectomy because those figures have not been released due to security concerns. Results All patients were men with a median age of 24 years (range 19–46 years) and a median initial Glasgow Coma Scale (GCS) score of 5 (range 3–14). At 6 months, 9 characteristics were statistically significant: focus of the initial injury, systemic infection, initial GCS score, initial GCS score excluding patients with a GCS score of 3, GCS score on arrival to the US, GCS score on dismissal from the medical center, Injury Severity Score, and patients with cerebrovascular injury. Six factors were significant at long-term follow-up: focus of initial injury, systemic infection, initial GCS score excluding patients with a GCS score of 3, GCS score on arrival to the US, and GCS score on dismissal from the medical center. At long-term follow-up, 7 (23%) of 30 patients had died, 5 (17%) of 30 had a GOS score of 2 or 3, and 18 (60%) of 30 had a GOS score of 4 or 5. Conclusions In this selected group of patients who underwent bilateral or bicompartmental craniectomy, 60% are independent at long-term follow-up. Patients with bifrontal injury fared best. Systemic infection and cerebrovascular injury corresponded with a worse outcome.

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Long-term follow-up and pregnancy after complete sacrectomy with lumbopelvic reconstruction: case report and literature review

BMC Pregnancy and Childbirth ◽

10.1186/s12884-015-0735-5 ◽

2016 ◽

Vol 16 (1) ◽

Cited By ~ 23

Author(s):

Valentin V. Barsan ◽

Valentina Briceño ◽

Manisha Gandhi ◽

Andrew Jea

Keyword(s):

Case Report ◽

Literature Review ◽

Long Term Follow Up

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WITHDRAWN: CLINICAL HETEROGENEITY OF THE ECTOPIC ACTH SYNDROME: A LONG-TERM FOLLOW UP STUDY

Endocrine Practice ◽

10.1016/j.eprac.2020.06.001 ◽

2020 ◽

Author(s):

Ana Laura Espinosa-de-los-Monteros ◽

Claudia Ramírez-Rentería ◽

Moisés Mercado

Keyword(s):

Ectopic Acth Syndrome ◽

Clinical Heterogeneity ◽

Ectopic Acth ◽

Follow Up Study ◽

Long Term Follow Up

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Hyperlipidemia in liver transplant patients: Persistence with long-term follow-up JS Crippin, BL Foster, SL Carlen, L Jennings, T Gonwa, R Goldstein, M Levy, B Husberg, G Klintmalm. Baylor University Medical Center, 3500 Gaston Avenue, Dallas, Texas, 75246

Hepatology ◽

10.1016/0270-9139(93)90436-q ◽

1993 ◽

Vol 18 (3) ◽

pp. 748

Keyword(s):

Liver Transplant ◽

Medical Center ◽

Transplant Patients ◽

Baylor University ◽

Long Term Follow Up

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A Role of brachytherapy in bilateral Wilms tumors: A long-term follow-up of three highly selected cases and literature review

Brachytherapy ◽

10.1016/j.brachy.2020.09.001 ◽

2020 ◽

Author(s):

Raquel Dávila Fajardo ◽

Bradley R. Pieters ◽

Jim C.H. Wilde ◽

Hugo A. Heij ◽

Rafal Chrzan ◽

...

Keyword(s):

Literature Review ◽

Long Term Follow Up

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Optical Coherent Tomography Predicts Long-Term Visual Outcome of Pituitary Adenoma Surgery: New Perspectives From a 5-Year Follow-up Study

Neurosurgery ◽

10.1093/neuros/nyaa318 ◽

2020 ◽

Vol 88 (1) ◽

pp. 106-112 ◽

Cited By ~ 1

Author(s):

Young Soo Chung ◽

Minkyun Na ◽

Jihwan Yoo ◽

Woohyun Kim ◽

In-Ho Jung ◽

...

Keyword(s):

Pituitary Adenoma ◽

Visual Field ◽

Assessment Tool ◽

Visual Fields ◽

Visual Field Defects ◽

Mean Deviation ◽

Rnfl Thickness ◽

Long Term Follow Up

Abstract BACKGROUND Compressive optic neuropathy is the most common indication for transsphenoidal surgery for pituitary adenomas. Optical coherence tomography (OCT) is a useful visual assessment tool for predicting postoperative visual field recovery. OBJECTIVE To analyze visual parameters and their association based on long-term follow-up. METHODS Only pituitary adenoma patients with abnormal visual field defects were selected. A total of 188 eyes from 113 patients assessed by visual field index (VFI) and 262 eyes from 155 patients assessed by mean deviation (MD) were enrolled in this study. Postoperative VFI, MD, and retinal nerve fiber layer (RNFL) thickness were evaluated and followed up. After classifying the patients into normal (>5%) and thin (<5%) RNFL groups, we investigated whether preoperative RNFL could predict visual field outcomes. We also observed how RNFL changes after surgery on a long-term basis. RESULTS Both preoperative VFI and MD had a linear proportional relationship with preoperative RNFL thickness. Sustained improvement of the visual field was observed after surgery in both groups, and the degree of improvement over time in each group was similar. RNFL thickness continued to decrease until 36 mo after surgery (80.2 ± 13.3 μm to 66.6 ± 11.9 μm) while visual field continued to improve (VFI, 61.8 ± 24.5 to 84.3 ± 15.4; MD, −12.9 ± 7.3 dB to −6.3 ± 5.9 dB). CONCLUSION Patients with thin preoperative RNFL may experience visual recovery similar to those with normal preoperative RNFL; however, the probability of normalized visual fields was not comparable. RNFL thickness showed a strong correlation with preoperative visual field defect. Long-term follow-up observation revealed a discrepancy between anatomic and functional recovery.

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Aggressive angiomyxoma in pregnancy: a case report and literature review

Journal of International Medical Research ◽

10.1177/0300060520936414 ◽

2020 ◽

Vol 48 (7) ◽

pp. 030006052093641

Author(s):

Haihua Xu ◽

Pengming Sun ◽

Rongli Xu ◽

Lihua Wang ◽

Yuequan Shi

Keyword(s):

Literature Review ◽

Child Outcomes ◽

Gonadotropin Releasing Hormone ◽

Aggressive Angiomyxoma ◽

Delivery Method ◽

Gonadotropin Releasing Hormone Agonist ◽

Long Term Follow Up ◽

In Pregnancy

Aggressive angiomyxoma is an interstitial tumour that is often misdiagnosed and is likely to recur. There have been few reported cases of angiomyxoma in pregnant women. We report a case of a woman who was previously diagnosed with a tumour in her vulva that increased in size during both of her pregnancies and spontaneously decreased postpartum. Local excision was performed and a gonadotropin-releasing hormone agonist was administered. According to a literature review, aggressive angiomyxoma is associated with good maternal and child outcomes. Caesarean section is not the delivery method of choice, but it is indicated if the tumour is preventing vaginal birth. Treatment for angiomyxoma is mainly postpartum local resection supplemented by hormone therapy. This tumour frequently recurs and patients should undergo long-term follow-up.

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Medulloblastoma: freedom from relapse longer than 8 years — a therapeutic cure?

Journal of Neurosurgery ◽

10.3171/jns.1991.75.4.0575 ◽

1991 ◽

Vol 75 (4) ◽

pp. 575-582 ◽

Cited By ~ 59

Author(s):

Mark G. Belza ◽

Sarah S. Donaldson ◽

Gary K. Steinberg ◽

Richard S. Cox ◽

Philip H. Cogen

Keyword(s):

Medical Center ◽

Survival Rates ◽

Adjunctive Treatment ◽

High Dose ◽

Content Type ◽

Significant Difference ◽

Long Term Follow Up ◽

Fine Print

✓ Seventy-seven patients presenting with medulloblastoma between 1958 and 1986 were treated at Stanford University Medical Center and studied retrospectively. Multimodality therapy utilized surgical extirpation followed by megavoltage irradiation. In 15 cases chemotherapy was used as adjunctive treatment. The 10- and 15-year actuarial survival rates were both 41% with an 18-year maximum follow-up period (median 4.75 years). There were no treatment failures after 8 years of tumor-free survival. Gross total removal of tumor was achieved in 22 patients (32%); the surgical mortality rate was 3.9%. No significant difference was noted in the incidence of metastatic disease between shunted and nonshunted patients. The classical form of medulloblastoma was present in 67% of cases while the desmoplastic subtype was found in 16%. Survival rates were best for patients presenting after 1970, for those with desmoplastic tumors, and for patients receiving high-dose irradiation (≥ 5000 cGy) to the posterior fossa. Although early data on freedom from relapse suggested a possible beneficial effect from chemotherapy, long-term follow-up results showed no advantage from this modality of treatment. The patterns of relapse and survival were examined; 64% of relapses occurred within the central nervous system, and Collins' rule was applicable in 83% of cases beyond the period of risk. Although patients treated for recurrent disease could be palliated, none were long-term survivors. The study data indicate that freedom from relapse beyond 8 years from diagnosis can be considered as a cure in this disease. Long-term follow-up monitoring is essential to determine efficacy of treatment and to assess survival patterns accurately.

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