Risk factors for tumor recurrence and progression of spindle cell oncocytoma of the pituitary gland: a systematic review and pooled analysis

Pituitary ◽  
2020 ◽  
Author(s):  
Huy Gia Vuong ◽  
Truong Phan Xuan Nguyen ◽  
Nguyen Pham ◽  
Ian F. Dunn
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Pituitary Gland ◽  
Tumor Recurrence ◽  
Spindle Cell ◽  
Pooled Analysis ◽  
Spindle Cell Oncocytoma

Differentially expressed miRNAs in spindle cell oncocytoma of the pituitary gland

2019 ◽  
Author(s):  
Lilla Krokker ◽  
Gabor Nyirő ◽  
Lilla Reininger ◽  
Otto Darvasi ◽  
Nikolette Szucs ◽  
...  
Keyword(s):  
Pituitary Gland ◽  
Spindle Cell ◽  
Differentially Expressed ◽  
Differentially Expressed Mirnas ◽  
Spindle Cell Oncocytoma

Arterial Embolization and Second-Look in Spindle Cell Oncocytoma of the Pituitary Gland: Case Report and Review of Literature

2020 ◽  
Vol 142 ◽  
pp. 87-92
Author(s):  
Leonardo Tariciotti ◽  
Antonio Arrichiello ◽  
Giorgio Fiore ◽  
Giulio Bertani ◽  
Giorgio Conte ◽  
...  
Keyword(s):  
Case Report ◽  
Pituitary Gland ◽  
Spindle Cell ◽  
Arterial Embolization ◽  
Review Of Literature ◽  
Second Look ◽  
Spindle Cell Oncocytoma

scholarly journals Worldwide risk factors for heart failure: A systematic review and pooled analysis

2013 ◽  
Vol 168 (2) ◽  
pp. 1186-1194 ◽  
Author(s):  
Shahab Khatibzadeh ◽  
Farshad Farzadfar ◽  
John Oliver ◽  
Majid Ezzati ◽  
Andrew Moran
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Systematic Review ◽  
Pooled Analysis

scholarly journals Spindle cell oncocytoma of the pituitary gland

2019 ◽  
Vol 131 (2) ◽  
pp. 517-525 ◽  
Author(s):  
Alexandra M. Giantini Larsen ◽  
David J. Cote ◽  
Hasan A. Zaidi ◽  
Wenya Linda Bi ◽  
Paul J. Schmitt ◽  
...  
Keyword(s):  
Pituitary Gland ◽  
Spindle Cell ◽  
Histopathological Examination ◽  
S100 Protein ◽  
Residual Tumor ◽  
Pituitary Hormones ◽  
Postoperative Management ◽  
Clinical Findings ◽  
Thyroid Transcription Factor 1 ◽  
Spindle Cell Oncocytoma

OBJECTIVEThe authors report the diagnosis, management, and outcomes of 6 cases of spindle cell oncocytoma (SCO) in an effort to guide clinical diagnosis and management of these uncommon lesions.METHODSThis study is a retrospective review of cases involving adult patients who underwent resection of pituitary lesions at the authors’ institutions between January 2000 and October 2017. The authors identified patients with histopathological confirmation of SCO and collected clinical data, including preoperative, perioperative, and postoperative management, complications, and outcomes.RESULTSSix patients with SCO were identified. Clinical findings at initial presentation included visual disturbances, dizziness, and headache. All patients underwent resection. Four resections were initially performed by the transsphenoidal approach, and 2 resections were performed by craniotomy at an outside institution with subsequent transsphenoidal reoperations. Neither necrosis nor increased mitotic activity was seen in the tumor samples. All samples stained positive for S100 protein and thyroid transcription factor 1 and negative for glial fibrillary acidic protein and pituitary hormones. Five of the samples stained positive for epithelial membrane antigen. The average MIB-1 index was 8.3% (range 2–17). Postoperatively, 3 of the 6 patients received further treatment for progression of residual tumor or for recurrence, 2 have stable residual tumor, and 1 has had no recurrence after gross-total resection. Two patients developed postoperative complications of transient sixth cranial nerve palsy and diplopia. There were no other complications.CONCLUSIONSSCO poses both a diagnostic and therapeutic challenge. These tumors are often initially misdiagnosed as nonfunctional pituitary adenomas because of their sellar location and nonspecific symptomatology. Postoperatively, SCO must also be distinguished from other neoplasms of the posterior pituitary gland through histopathological examination. Resection of SCO can be challenging, given its highly vascular and adherent nature. Long-term follow-up is critical, as the tumor is associated with higher recurrence and progression rates compared to other benign neoplasms of the sella.

scholarly journals Teaching NeuroImage: Spindle cell oncocytoma of the pituitary gland

Neurology ◽  
2008 ◽  
Vol 71 (2) ◽  
pp. e3-e3 ◽  
Author(s):  
M. U. Farooq ◽  
A. Bhatt ◽  
H. T. Chang
Keyword(s):  
Pituitary Gland ◽  
Spindle Cell ◽  
Spindle Cell Oncocytoma

A Comprehensive Study of Spindle Cell Oncocytoma of the Pituitary Gland: Series of 6 Cases and Meta-Analysis of 85 Cases

2021 ◽  
Vol 149 ◽  
pp. e197-e216
Author(s):  
Hirotaka Hasegawa ◽  
Jamie J. Van Gompel ◽  
Soliman H. Oushy ◽  
Bruce E. Pollock ◽  
Michael J. Link ◽  
...  
Keyword(s):  
Pituitary Gland ◽  
Spindle Cell ◽  
Meta Analysis ◽  
Spindle Cell Oncocytoma ◽  
Comprehensive Study
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