Characterization of Defense Signaling Pathways of Brassica napus and Brassica carinata in Response to Sclerotinia sclerotiorum Challenge

2009 ◽  
Vol 28 (2) ◽  
pp. 253-263 ◽  
Author(s):  
Bo Yang ◽  
Muhammad H. Rahman ◽  
Yue Liang ◽  
Saleh Shah ◽  
Nat N. V. Kav
2004 ◽  
Vol 41 (8) ◽  
pp. 754-765 ◽  
Author(s):  
Rugang Li ◽  
Roger Rimmer ◽  
Lone Buchwaldt ◽  
Andrew G Sharpe ◽  
Ginette Séguin-Swartz ◽  
...  

1990 ◽  
Vol 94 (4) ◽  
pp. 1887-1896 ◽  
Author(s):  
Clint C. S. Chapple ◽  
John R. Glover ◽  
Brian E. Ellis

2020 ◽  
Vol 39 (6) ◽  
pp. 709-722 ◽  
Author(s):  
Zheng Wang ◽  
Lu-Yue Ma ◽  
Xiao Li ◽  
Feng-Yun Zhao ◽  
Rehman Sarwar ◽  
...  

2020 ◽  
Vol 20 ◽  
Author(s):  
Ammad Ahmad Farooqi ◽  
Evangelia Legaki ◽  
Maria Gazouli ◽  
Silvia Rinaldi ◽  
Rossana Berardi

: Central dogma of molecular biology has remained cornerstone of classical molecular biology but serendipitous discovery of microRNAs (miRNAs) in nematodes paradigmatically shifted our current understanding of the intricate mech-anisms which occur during transitions from transcription to translation. Discovery of miRNA captured tremendous attention and appreciation and we had witnessed an explosion in the field of non-coding RNAs. Ground-breaking discoveries in the field of non-coding RNAs have helped in better characterization of microRNAs and long non-coding RNAs (LncRNAs). There is an ever-increasing list of miRNA targets which are regulated by MALAT1 to stimulate or repress expression of tar-get genes. However, in this review our main focus is to summarize mechanistic insights related to MALAT1-mediated regu-lation of oncogenic signaling pathways. We have discussed how MALAT1 modulated TGF/SMAD and Hippo pathways in various cancers. We have also comprehensively summarized how JAK/STAT and Wnt/β-catenin pathways stimulated MALAT1 expression and consequentially how MALAT1 potentiated these signaling cascades to promote cancer. MALAT1 research has undergone substantial broadening however, there is still a need to identify additional mechanisms. MALAT1 is involved in multi-layered regulation of multiple transduction cascades and detailed analysis of different pathways will be helpful in getting a step closer to individualized medicine.


2020 ◽  
Vol 21 (18) ◽  
pp. 6623 ◽  
Author(s):  
Marc Bienz ◽  
Salima Ramdani ◽  
Hans Knecht

Our understanding of the tumorigenesis of classical Hodgkin lymphoma (cHL) and the formation of Reed–Sternberg cells (RS-cells) has evolved drastically in the last decades. More recently, a better characterization of the signaling pathways and the cellular interactions at play have paved the way for new targeted therapy in the hopes of improving outcomes. However, important gaps in knowledge remain that may hold the key for significant changes of paradigm in this lymphoma. Here, we discuss the past, present, and future of cHL, and review in detail the more recent discoveries pertaining to genetic instability, anti-apoptotic signaling pathways, the tumoral microenvironment, and host-immune system evasion in cHL.


1996 ◽  
Vol 8 (12) ◽  
pp. 2369-2380 ◽  
Author(s):  
K Yu ◽  
U Schafer ◽  
T L Glavin ◽  
D R Goring ◽  
S J Rothstein

2021 ◽  
pp. 126754
Author(s):  
Igor Daniel Alves Ribeiro ◽  
Evelise Bach ◽  
Fernanda da Silva Moreira ◽  
Aline Reis Müller ◽  
Caroline Pinto Rangel ◽  
...  

Gene ◽  
2003 ◽  
Vol 310 ◽  
pp. 113-121 ◽  
Author(s):  
S Vacher ◽  
P Cotton ◽  
M Fèvre

Sign in / Sign up

Export Citation Format

Share Document