Vincristine induces procoagulant activity of the human lymphoblastic leukemia cell line Jurkat through the release of extracellular vesicles

2019 ◽  
Vol 48 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Claire Pluchart ◽  
Gael Poitevin ◽  
Maud Colinart-Thomas ◽  
Gregory Guimard ◽  
Sandra Audonnet ◽  
...  
2003 ◽  
Vol 37 (1) ◽  
pp. 84-91 ◽  
Author(s):  
Roderick A.F. MacLeod ◽  
Stefan Nagel ◽  
Maren Kaufmann ◽  
Johannes W.G. Janssen ◽  
Hans G. Drexler

RSC Advances ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 1679-1684 ◽  
Author(s):  
Yu-Na Wang ◽  
Jing Wang ◽  
Hao-Nan Yang ◽  
Bang-Lei Zhang ◽  
Pan Zhang ◽  
...  

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy, and commonly associated with activating mutations in the Notch1 pathway.


In Vitro ◽  
1984 ◽  
Vol 20 (11) ◽  
pp. 884-888
Author(s):  
Joseph Yourno ◽  
William A. Samsonoff ◽  
Ann Willey ◽  
Peter Burkhart ◽  
Frank Lizzi ◽  
...  

Blood ◽  
1981 ◽  
Vol 57 (2) ◽  
pp. 368-371
Author(s):  
G Steinmann ◽  
R Mertelsmann ◽  
E deHarven ◽  
MA Moore

Using an electronmicroscopic peroxidase-antiperoxidase technique in combination with a three-step fixation procedure according to Willingham, the ultrastructural site of terminal deoxynucleotidyl transferase (TdT) could be shown in cells of a human lymphoblastic leukemia cell line (MOLT 4). TdT appeared in the cytoplasm of the cells associated with large membrane bound granules from 150 to 600 nm in diameter usually arranged in aggregates. TdT-positive spaces were completely segregated form the rest of the cytoplasm and seemed to be interconnected by a tubular system. No TdT was detected in the nuclei.


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