This paper discusses data synthesis of production and facility knowledge for sustainability analysis by applying the ISA–95 “Activity Models of Manufacturing Operations Management” (MOM) model. Presently, production and facility management basically function independently of each other. This paper presents the addition of facility activities to the MOM model, in accordance with the needs for attaining a holistic view of sustainability analysis. Historically, production and facility data are represented in various forms, e.g., data bases, CAD, and spread-sheets, without a common unifying representation. Based on this combination of incompatible modeling tools, the use of Core Manufacturing Simulation Data (CMSD) is proposed as a standard framework for integrating the broad range of technology. A case study of the data synthesis for a precision sand casting production facility is explored.