scholarly journals Obesity and Gastroesophageal Reflux: Quantifying the Association Between Body Mass Index, Esophageal Acid Exposure, and Lower Esophageal Sphincter Status in a Large Series of Patients with Reflux Symptoms

2009 ◽  
Vol 13 (8) ◽  
pp. 1440-1447 ◽  
Author(s):  
Shahin Ayazi ◽  
Jeffrey A. Hagen ◽  
Linda S. Chan ◽  
Steven R. DeMeester ◽  
Molly W. Lin ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Gastroesophageal Reflux ◽  
Lower Esophageal Sphincter ◽  
Body Mass ◽  
Esophageal Acid Exposure ◽  
Large Series ◽  
Acid Exposure ◽  
Reflux Symptoms ◽  
Esophageal Sphincter

scholarly journals Su1523 The Status of the Lower Esophageal Sphincter at Rest and the Degree of Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease

2012 ◽  
Vol 142 (5) ◽  
pp. S-1054-S-1055
Author(s):  
Shahin Ayazi ◽  
Jeffrey A. Hagen ◽  
Joerg Zehetner ◽  
Kimberly S. Grant ◽  
Michael Hermansson ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Lower Esophageal Sphincter ◽  
Reflux Disease ◽  
Esophageal Acid Exposure ◽  
Acid Exposure ◽  
The Status ◽  
Esophageal Sphincter

Esophageal Acid Exposure in Upright and Recumbent Postures: Roles of Lower Esophageal Sphincter, Esophageal Contractile and Transport Function, Hiatal Hernia, Age, Sex, and Body Mass

2006 ◽  
Vol 51 (11) ◽  
pp. 1896-1903 ◽  
Author(s):  
Georg Stacher ◽  
Johannes Lenglinger ◽  
Margit Eisler ◽  
Martha Hoffmann ◽  
Alexandra Goll ◽  
...  
Keyword(s):  
Hiatal Hernia ◽  
Lower Esophageal Sphincter ◽  
Body Mass ◽  
Esophageal Acid Exposure ◽  
Acid Exposure ◽  
Transport Function ◽  
Esophageal Sphincter

scholarly journals Influence of exercise testing in gastroesophageal reflux in patients with gastroesophageal reflux disease

2014 ◽  
Vol 27 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Antonio Moreira MENDES-FILHO ◽  
Joaquim Prado Pinto MORAES-FILHO ◽  
Ary NASI ◽  
Jaime Natan EISIG ◽  
Tomas Navarro RODRIGUES ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Lower Esophageal Sphincter ◽  
Body Mass ◽  
Reflux Disease ◽  
Disease Group ◽  
Erosive Disease ◽  
Esophageal Sphincter

Background : Gastroesophageal reflux disease is a worldwide prevalent condition that exhibits a large variety of signs and symptoms of esophageal or extra-esophageal nature and can be related to the esophagic adenocarcinoma. In the last few years, greater importance has been given to the influence of physical exercises on it. Some recent investigations, though showing conflicting results, point to an exacerbation of gastroesophageal reflux during physical exercises. Aim : To evaluate the influence of physical activities in patients presenting with erosive and non erosive disease by ergometric stress testing and influence of the lower esophageal sphincter tonus and body mass index during this situation. Methods : Twenty-nine patients with erosive disease (group I) and 10 patients with non-erosive disease (group II) were prospectively evaluated. All the patients were submitted to clinical evaluation, followed by upper digestive endoscopy, manometry and 24 h esophageal pH monitoring. An ergometric testing was performed 1 h before removing the esophageal pH probe. During the ergometric stress testing, the following variables were analyzed: test efficacy, maximum oxygen uptake, acid reflux duration, gastroesophageal reflux symptoms, influence of the lower esophageal sphincter tonus and influence of body mass index in the occurrence of gastroesophageal reflux during these physical stress. Results : Maximum oxigen consumption or VO 2 max, showed significant correlation when it was 70% or higher only in the erosive disease group, evaluating the patients with or without acid reflux during the ergometric testing (p=0,032). The other considered variables didn't show significant correlations between gastroesophageal reflux and physical activity (p>0,05). Conclusions : 1) Highly intensive physical activity can predispose the occurrence of gastroesophageal reflux episodes in gastroesophageal reflux disease patients with erosive disease; 2) light or short sessions of physical activity have no influence on reflux, regardless of body mass index; 3) the lower esophageal sphincter tonus does not influence the occurrence of reflux disease episodes during exercise testing.

Food and Gastroesophageal Reflux Disease

2019 ◽  
Vol 26 (19) ◽  
pp. 3497-3511 ◽  
Author(s):  
Teodora Surdea-Blaga ◽  
Dana E. Negrutiu ◽  
Mariana Palage ◽  
Dan L. Dumitrascu
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Lower Esophageal Sphincter ◽  
Reflux Disease ◽  
Current Knowledge ◽  
Positive Association ◽  
Sphincter Pressure ◽  
Low Carbohydrate Diet ◽  
Reflux Symptoms ◽  
Esophageal Sphincter

Gastroesophageal reflux disease is a chronic condition with a high prevalence in western countries. Transient lower esophageal sphincter relaxation episodes and a decreased lower esophageal sphincter pressure are the main mechanisms involved. Currently used drugs are efficient on reflux symptoms, but only as long as they are administered, because they do not modify the reflux barrier. Certain nutrients or foods are generally considered to increase the frequency of gastroesophageal reflux symptoms, therefore physicians recommend changes in diet and some patients avoid bothering foods. This review summarizes current knowledge regarding food and gastroesophageal reflux. For example, fat intake increases the perception of reflux symptoms. Regular coffee and chocolate induce gastroesophageal reflux and increase the lower esophageal exposure to acid. Spicy foods might induce heartburn, but the exact mechanism is not known. Beer and wine induce gastroesophageal reflux, mainly in the first hour after intake. For other foods, like fried food or carbonated beverages data on gastroesophageal reflux is scarce. Similarly, there are few data about the type of diet and gastroesophageal reflux. Mediterranean diet and a very low carbohydrate diet protect against reflux. Regarding diet-related practices, consistent data showed that a “short-meal-to-sleep interval” favors reflux episodes, therefore some authors recommend that dinner should be at least four hours before bedtime. All these recommendations should consider patient’s weight, because several meta-analyses showed a positive association between increased body mass index and gastroesophageal reflux disease.

Lower esophageal sphincter characteristics and esophageal acid exposure following partial or 360‡ fundoplication: Results of a prospective, randomized, clinical study

1991 ◽  
Vol 15 (1) ◽  
pp. 115-120 ◽  
Author(s):  
Lars Lundell ◽  
Hasse Abrahamsson ◽  
Magnus Ruth ◽  
Nils Sandberg ◽  
Lars C. Olbe
Keyword(s):  
Clinical Study ◽  
Lower Esophageal Sphincter ◽  
Esophageal Acid Exposure ◽  
Acid Exposure ◽  
Randomized Clinical Study ◽  
Esophageal Sphincter

Zero-Inflated Models for Identifying Relationships Between Body Mass Index and Gastroesophageal Reflux Symptoms: A Nationwide Population-Based Study in China

2016 ◽  
Vol 61 (7) ◽  
pp. 1986-1995 ◽  
Author(s):  
Qin Xu ◽  
Wei Zhang ◽  
Tianyi Zhang ◽  
Ruijie Zhang ◽  
Yanfang Zhao ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Gastroesophageal Reflux ◽  
Body Mass ◽  
Population Based ◽  
Population Based Study ◽  
Reflux Symptoms

Waist to hip ratio is a better predictor of esophageal acid exposure than body mass index

2017 ◽  
Vol 29 (7) ◽  
pp. e13033 ◽  
Author(s):  
C. Ringhofer ◽  
J. Lenglinger ◽  
M. Riegler ◽  
I. Kristo ◽  
A. Kainz ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Esophageal Acid Exposure ◽  
Acid Exposure ◽  
Waist To Hip Ratio
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