Implications of Lymph Node Evaluation in Crohn’s Patients with Small-Bowel Adenocarcinoma

2021 ◽  
Author(s):  
Richard J. Straker ◽  
Adrienne B. Shannon ◽  
Robert R. Roses ◽  
Douglas L. Fraker ◽  
Najjia N. Mahmoud ◽  
...  
Keyword(s):  
Lymph Node ◽  
Small Bowel ◽  
Small Bowel Adenocarcinoma ◽  
Lymph Node Evaluation

scholarly journals Prognostic value of lymph node evaluation in small bowel adenocarcinoma

Cancer ◽  
2010 ◽  
Vol 116 (23) ◽  
pp. 5374-5382 ◽  
Author(s):  
Michael J. Overman ◽  
Chung-Yuan Hu ◽  
Robert A. Wolff ◽  
George J. Chang
Keyword(s):  
Lymph Node ◽  
Small Bowel ◽  
Prognostic Value ◽  
Small Bowel Adenocarcinoma ◽  
Lymph Node Evaluation

Small Intestine: Adenocarcinoma

2017 ◽  
Author(s):  
Joel M Baumgartner ◽  
Sudeep Banerjee ◽  
Jason K Sicklick
Keyword(s):  
Lymph Node ◽  
Small Bowel ◽  
Systemic Chemotherapy ◽  
Imaging Techniques ◽  
Distant Metastases ◽  
Lymph Node Involvement ◽  
Small Bowel Adenocarcinoma ◽  
Stage Disease ◽  
Node Involvement ◽  
Inflammatory Bowel

Adenocarcinoma is the second most common nonduodenal small bowel tumor. Small bowel adenocarcinoma has risk factors similar to those of colorectal adenocarcinoma but is rarer and less well understood. Diagnosis relies on advanced imaging techniques as well as endoscopy or enteroscopy for tissue diagnosis. Aggressive biology and vague symptoms in early disease cause a majority of patients to present with late-stage disease. Adenocarcinomas with lymph node involvement should be treated with resection and systemic chemotherapy. In contrast, systemic chemotherapy alone should be employed in cases with distant metastases unless the primary tumor is bleeding, perforated, or causing a bowel obstruction.   This review contains 4 figures, 5 tables and 17 references Key words: adenocarcinoma, chemotherapy, enteroscopy, hereditary syndrome, inflammatory bowel disease, lymph node, mesentery, small bowel  

Small Intestine: Adenocarcinoma

2017 ◽  
Author(s):  
Joel M Baumgartner ◽  
Sudeep Banerjee ◽  
Jason K Sicklick
Keyword(s):  
Lymph Node ◽  
Small Bowel ◽  
Systemic Chemotherapy ◽  
Imaging Techniques ◽  
Distant Metastases ◽  
Lymph Node Involvement ◽  
Small Bowel Adenocarcinoma ◽  
Stage Disease ◽  
Node Involvement ◽  
Inflammatory Bowel

Adenocarcinoma is the second most common nonduodenal small bowel tumor. Small bowel adenocarcinoma has risk factors similar to those of colorectal adenocarcinoma but is rarer and less well understood. Diagnosis relies on advanced imaging techniques as well as endoscopy or enteroscopy for tissue diagnosis. Aggressive biology and vague symptoms in early disease cause a majority of patients to present with late-stage disease. Adenocarcinomas with lymph node involvement should be treated with resection and systemic chemotherapy. In contrast, systemic chemotherapy alone should be employed in cases with distant metastases unless the primary tumor is bleeding, perforated, or causing a bowel obstruction.   This review contains 4 figures, 5 tables and 17 references Key words: adenocarcinoma, chemotherapy, enteroscopy, hereditary syndrome, inflammatory bowel disease, lymph node, mesentery, small bowel  

scholarly journals A rare case of jejunal adenocarcinoma with brain metastasis

2021 ◽  
Author(s):  
M. Harish ◽  
N. Hariprasad ◽  
R. Kannan
Keyword(s):  
Lymph Node ◽  
Small Bowel ◽  
Brain Metastasis ◽  
Delayed Diagnosis ◽  
Late Presentation ◽  
Lower Limbs ◽  
Jejunal Loop ◽  
Wall Thickening ◽  
Small Bowel Adenocarcinoma ◽  
Regional Lymphadenectomy

Small bowel malignancies are rare entity, with adenocarcinoma being one of common type along with neuroendocrine tumours. Associated with Crohns, celiac disease, FAP and HNPCC. Jejunal adenocarcinoma produce vague symptoms, accounting for late presentation leading to difficult and delayed diagnosis in favour of poor prognosis. Diagnosis is established by CECT abdomen and CEA levels. Ro resection with regional lymphadenectomy and jejunojejunal anastomosis is preferred followed by adjuvant FOLFOX chemotherapy. Here we presenting a 68 years old male, anaemic with vague abdominal pain for 3 months, CECT showed malignant wall thickening involving 10 cm of proximal jejunal loop with no enlarged lymph nodes and CEA was elevated. Proceeded with laparotomy, an irregular hard mass of 10×10 cm involving 20 cm of jejunum with transverse colon infiltration with multiple mesenteric nodes found, composite resection with jejunojejunostomy and colocolic anastomosis done. Histopathology showed poorly differentiated jejunal adenocarcinoma with colonic infiltration with reactive nodes and post operatively on day 7, patient developed seizures and weakness of left upper and lower limbs, MRI brain showed solitary metastasis 2×2 cm in right frontal region and PET CT showed brain metastasis and multiple intraabdominal lymph node, lung and prostate metastasis, planned SBRT for brain metastasis and palliative chemotherapy. Lymph node, liver and peritoneum are common site of metastasis for small bowel adenocarcinoma, very rarely brain metastasis can occur in short time and to be considered if neurological symptoms occur pre and postoperatively.

Prognostic relevance of lymph node ratio and total lymph node count for small bowel adenocarcinoma

Surgery ◽  
2015 ◽  
Vol 158 (2) ◽  
pp. 486-493 ◽  
Author(s):  
Thuy B. Tran ◽  
Motaz Qadan ◽  
Monica M. Dua ◽  
Jeffrey A. Norton ◽  
George A. Poultsides ◽  
...  
Keyword(s):  
Lymph Node ◽  
Small Bowel ◽  
Lymph Node Ratio ◽  
Small Bowel Adenocarcinoma ◽  
Lymph Node Count ◽  
Prognostic Relevance ◽  
Node Ratio ◽  
Node Count ◽  
Total Lymph Node

Prognostic relevance of programmed death-ligand 1 expression and microsatellite status in small bowel adenocarcinoma

2020 ◽  
Vol 55 (3) ◽  
pp. 321-329
Author(s):  
Johannes Klose ◽  
Felix Lasitschka ◽  
Cornelia Horsch ◽  
Moritz J. Strowitzki ◽  
Thomas Bruckner ◽  
...  
Keyword(s):  
Small Bowel ◽  
Small Bowel Adenocarcinoma ◽  
Programmed Death Ligand 1 ◽  
Prognostic Relevance ◽  
Programmed Death
Sign in / Sign up

Export Citation Format

Share Document