scholarly journals Acute Hypoxemic Respiratory Failure with High Clinical Suspicion of COVID-19 Despite Negative PCR: a Case for Empiric Corticosteroids and Role of Serum Antibody in Diagnosis

2021 ◽  
Author(s):  
Vannesa Cederstrom ◽  
Heidi Erickson ◽  
James Leatherman
Keyword(s):  
Respiratory Failure ◽  
Serum Antibody ◽  
Clinical Suspicion ◽  
Hypoxemic Respiratory Failure ◽  
Acute Hypoxemic Respiratory Failure ◽  
High Clinical Suspicion

scholarly journals The Role of Noninvasive Respiratory Management in Patients with Severe COVID-19 Pneumonia

2021 ◽  
Vol 11 (9) ◽  
pp. 884
Author(s):  
Evangelia Akoumianaki ◽  
Eleni Ischaki ◽  
Konstantinos Karagiannis ◽  
Ioanna Sigala ◽  
Spyros Zakyn-thinos
Keyword(s):  
Respiratory Failure ◽  
Invasive Mechanical Ventilation ◽  
Healthcare Personnel ◽  
Close Monitoring ◽  
Hypoxemic Respiratory Failure ◽  
Acute Hypoxemic Respiratory Failure ◽  
Respiratory Management ◽  
Rate Of Success ◽  
Selection Of

Acute hypoxemic respiratory failure is the principal cause of hospitalization, invasive mechanical ventilation and death in severe COVID-19 infection. Nearly half of intubated patients with COVID-19 eventually die. High-Flow Nasal Oxygen (HFNO) and Noninvasive Ventilation (NIV) constitute valuable tools to avert endotracheal intubation in patients with severe COVID-19 pneumonia who do not respond to conventional oxygen treatment. Sparing Intensive Care Unit beds and reducing intubation-related complications may save lives in the pandemic era. The main drawback of HFNO and/or NIV is intubation delay. Cautious selection of patients with severe hypoxemia due to COVID-19 disease, close monitoring and appropriate employment and titration of HFNO and/or NIV can increase the rate of success and eliminate the risk of intubation delay. At the same time, all precautions to protect the healthcare personnel from viral transmission should be taken. In this review, we summarize the evidence supporting the application of HFNO and NIV in severe COVID-19 hypoxemic respiratory failure, analyse the risks associated with their use and provide a path for their proper implementation.

scholarly journals Cryoprobe biopsy for the diagnosis of acute hypoxemic respiratory failure of undetermined origin

2019 ◽  
Vol 21 (2) ◽  
pp. 119-123
Author(s):  
Marcos J Las Heras ◽  
Jose Dianti ◽  
Manuel Tisminetzky ◽  
Graciela Svetliza ◽  
Sergio E Giannasi ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Diagnostic Yield ◽  
Specific Treatment ◽  
Case Series ◽  
Safe Procedure ◽  
Hypoxemic Respiratory Failure ◽  
Acute Hypoxemic Respiratory Failure ◽  
Select Group ◽  
Lung Sample ◽  
Appropriate Treatment

Rationale Acute hypoxemic respiratory failure is a condition that comprises a wide array of entities. Obtaining a histological lung sample might help reach a diagnosis and direct an appropriate treatment in a select group of patients. Objective To describe our experience in the use of cryobiopsy for the diagnosis of acute hypoxemic respiratory failure of undetermined origin. Methods Retrospective analysis of case series of patients with acute hypoxemic respiratory failure who underwent lung cryobiopsy at the Intensive Care Unit of the Hospital Italiano de Buenos Aires, Argentina. Results Cryobiopsy yielded a histological diagnosis in all patients ( n = 10, 100%). This led to either a change in therapy or continuation of a specific treatment in eight of these patients. Cryobiopsy was found to be contributive in all the patients who did not meet Berlin criteria for acute respiratory distress syndrome. No major complications were associated with the procedure. Conclusions Cryobiopsy is a safe procedure with a high diagnostic yield in a selected group of patients.

Noninvasive ventilation in acute hypoxemic respiratory failure: A systematic review and meta-analysis. Response to letter

2019 ◽  
Vol 50 ◽  
pp. 310
Author(s):  
Paula G. David-João ◽  
Murilo H. Guedes ◽  
Alvaro Réa-Neto ◽  
Viviane B. de Oliveira Chaiben ◽  
Cristina P. Baena
Keyword(s):  
Systematic Review ◽  
Respiratory Failure ◽  
Noninvasive Ventilation ◽  
Meta Analysis ◽  
Hypoxemic Respiratory Failure ◽  
Acute Hypoxemic Respiratory Failure
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