scholarly journals Overall survival time prediction for high-grade glioma patients based on large-scale brain functional networks

2018 ◽  
Vol 13 (5) ◽  
pp. 1333-1351 ◽  
Author(s):  
Luyan Liu ◽  
Han Zhang ◽  
Jinsong Wu ◽  
Zhengda Yu ◽  
Xiaobo Chen ◽  
...  
Keyword(s):  
Overall Survival ◽  
Survival Time ◽  
Large Scale ◽  
High Grade Glioma ◽  
Functional Networks ◽  
High Grade ◽  
Time Prediction ◽  
Overall Survival Time ◽  
Brain Functional Networks

scholarly journals Post-Hoc Overall Survival Time Prediction From Brain MRI

2021 ◽  
Author(s):  
Renato Hermoza ◽  
Gabriel Maicas ◽  
Jacinto C. Nascimento ◽  
Gustavo Carneiro
Keyword(s):  
Overall Survival ◽  
Survival Time ◽  
Brain Mri ◽  
Time Prediction ◽  
Overall Survival Time ◽  
Post Hoc

TH-E-BRF-05: Comparison of Survival-Time Prediction Models After Radiotherapy for High-Grade Glioma Patients Based On Clinical and DVH Features

2014 ◽  
Vol 41 (6Part33) ◽  
pp. 570-570 ◽  
Author(s):  
T Magome ◽  
A Haga ◽  
H Igaki ◽  
N Sekiya ◽  
Y Masutani ◽  
...  
Keyword(s):  
Survival Time ◽  
Prediction Models ◽  
High Grade Glioma ◽  
High Grade ◽  
Time Prediction

Altered interplay among large-scale brain functional networks underpins multi-domain anosognosia in early-AD

2021 ◽  
Vol 429 ◽  
pp. 118315
Author(s):  
Jose Manuel Valera Bermejo ◽  
Matteo De Marco ◽  
Annalena Venneri
Keyword(s):  
Large Scale ◽  
Functional Networks ◽  
Brain Functional Networks

scholarly journals Involvement of Indoleamine 2,3-Dioxygenase in Impairing Tumor-Infiltrating CD8+T-Cell Functions in Esophageal Squamous Cell Carcinoma

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Ge Zhang ◽  
Wan-Li Liu ◽  
Lin Zhang ◽  
Jun-Ye Wang ◽  
Miao-Huan Kuang ◽  
...  
Keyword(s):  
Overall Survival ◽  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Survival Time ◽  
Squamous Cell ◽  
Tumor Immune Escape ◽  
Cell Functions ◽  
Indoleamine 2,3 Dioxygenase ◽  
Overall Survival Time

The indoleamine 2,3-dioxygenase-(IDO-) mediated microenvironment plays an important role in tumor immune escape. However, the inhibitory effects of IDO on the CD8+tumour-infiltrating lymphocytes (CD8+TILs) in esophageal squamous cell carcinoma (ESCC) have not been clarified yet. Here, we found that the level of IDO expression in ESCC tumor specimens correlated with a reduction in the number of CD8+TILs. Patients with high IDO expression and a low number of CD8+TILs had significantly impaired overall survival time. IDO expression and functional enzyme activity in ESCC cell lines could be induced by IFNγ. When exposed to the milieu generated by IDO-expressing Eca109 cells, the CD8+TILs were suppressed in proliferation, and their cytolytic functions against target tumor cells were lost. These results suggested that impairing CD8+TIL functions by IDO expressed in ESCC possibly contributed to the finding that patients with higher IDO expression have more aggressive disease progression and shorter overall survival time.

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