GLP-1 and Adiponectin: Effect of Weight Loss After Dietary Restriction and Gastric Bypass in Morbidly Obese Patients with Normal and Abnormal Glucose Metabolism

2008 ◽  
Vol 19 (3) ◽  
pp. 313-320 ◽  
Author(s):  
Camila Puzzi de Carvalho ◽  
Daniela Miguel Marin ◽  
Aglécio Luiz de Souza ◽  
José Carlos Pareja ◽  
Elintom Adami Chaim ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Glucose Metabolism ◽  
Dietary Restriction ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Abnormal Glucose Metabolism

scholarly journals Association of Circulating Irisin Concentrations with Weight Loss after Roux-en-Y Gastric Bypass Surgery

2019 ◽  
Vol 16 (4) ◽  
pp. 660 ◽  
Author(s):  
Yeon Lee ◽  
Yoonseok Heo ◽  
Ji-Ho Choi ◽  
Sunghyouk Park ◽  
Kyoung Kim ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Excess Weight Loss ◽  
Gastric Bypass Surgery ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Preoperative Serum ◽  
One Year

Irisin is a myokine with potential anti-obesity properties that has been suggested to increase energy expenditure in obese patients. However, there is limited clinical information on the biology of irisin in humans, especially in morbidly obese patients undergoing bariatric surgery. We aimed to assess the association of circulating irisin concentrations with weight loss in obese patients undergoing bariatric surgery. This was a pilot, single-centre, longitudinal observational study. We recruited 25 morbidly obese subjects who underwent Roux-en-Y gastric bypass surgery (RYGBP), and blood samples from 12 patients were taken to measure serum irisin concentrations before, and one and nine months after surgery. Their clinical characteristics were measured for one year. The preoperative serum irisin concentration (mean 1.01 ± 0.23 μg/mL, range 0.73–1.49) changed bidirectionally one month after RYGBP. The mean concentration at nine months was 1.11 ± 0.15 μg/mL (range 0.92–1.35). Eight patients had elevated irisin levels compared with their preoperative values, but four did not. Elevations of irisin levels nine months, but not one month, after surgery, were associated with lower preoperative levels (p = 0.016) and worse weight reduction rates (p = 0.006 for the percentage excess weight loss and p = 0.032 for changes in body mass index). The preoperative serum irisin concentrations were significantly correlated with the percentage of excess weight loss for one year (R2 = 0.612; p = 0.04) in our study. Our results suggest that preoperative circulating irisin concentrations may be at least in part associated with a weight loss effect of bariatric surgery in morbidly obese patients. Further large-scale clinical studies are needed to ratify these findings.

PL-206: Protein intake compliane of morbidly obese patients undergoing laparoscopic Roux-en-Y gastric bypass and its effect on weight loss, leptin and albumin

2010 ◽  
Vol 6 (3) ◽  
pp. S11-S12
Author(s):  
Kristine O'Hara ◽  
Bruce Bernstein ◽  
Ravi Chhatrala ◽  
Balaji Jangam ◽  
Judy Carty ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Protein Intake ◽  
Morbidly Obese ◽  
Obese Patients

scholarly journals EARLY WEIGHT LOSS OUTCOMES AND GLUCOSE METABOLISM PARAMETERS AFTER BANDED VERSUS NON-BANDED ONE ANASTOMOSIS GASTRIC BYPASS: A PROSPECTIVE RANDOMIZED TRIAL

2019 ◽  
Vol 56 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Everton CAZZO ◽  
Felipe Gilberto VALERINI ◽  
Fábio Henrique Mendonça CHAIM ◽  
Pedro França da Costa SOARES ◽  
Almino Cardoso RAMOS ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Glucose Metabolism ◽  
Randomized Study ◽  
Standard Technique ◽  
One Anastomosis Gastric Bypass ◽  
Morbidly Obese ◽  
Model Assessment ◽  
Post Surgery ◽  
Early Weight Loss

ABSTRACT BACKGROUND: The influence of the placement of a band on the outcomes of one anastomosis gastric bypass (OAGB) has not been appropriately studied yet. OBJECTIVE: To compare early weight loss and glucose metabolism parameters following banded versus non-banded OAGB. METHODS: A prospective randomized study, which evaluated 20 morbidly obese individuals who underwent banded and non-banded OAGB and were followed-up for three months. Weight loss (percentage of excess weight loss - %EWL and percentage of body mass index loss - %BMIL) and glucose metabolism outcomes (glucose, insulin and homeostasis model assessment - HOMA) were compared. RESULTS: The banded group presented a significantly higher %EWL at one month (29.6±5.5% vs 17.2±3.4%; P<0.0001) and two months post-surgery (46±7% vs 34.2±9%; P=0.004544), as well as a significantly higher %BMIL at one month (9.7±1.1% vs 5.8±0.8%; P<0.0001), two months (15±1.4% vs 11.5±2.1; P=0.000248), and three months (18.8±1.8% vs 15.7±3.2%; P=0.016637). At three months, banded OAGB led to significant decreases of insulin (14.4±4.3 vs 7.6±1.9; P=0.00044) and HOMA (3.1±1.1 vs 1.5±0.4; P=0.00044), whereas non-banded OAGB also led to significant decreases of insulin (14.8±7.6 vs 7.8±3.1; P=0.006) and HOMA (3.2±1.9 vs 1.6±0.8; P=0.0041). The percent variation of HOMA did not significantly differ between banded and non-banded OAGB (P=0.62414); overall, the percent variation of HOMA was not correlated with %EWL (P=0.96988) or %BMIL (P=0.82299). CONCLUSION: Banded OAGB led to a higher early weight loss than the standard technique. Banded and non-banded OAGB led to improvements in insulin resistance regardless of weight loss.

QS83. Muscle Loss Constitutes A Significant Component of Body Weight Loss in Morbidly Obese Patients Following Laparoscopic Roux-en-Y Gastric Bypass (LRYGB)

2008 ◽  
Vol 144 (2) ◽  
pp. 301-302
Author(s):  
Aaron W. Eckhauser ◽  
Homaira Ayesha Hossain ◽  
Pamela A. Marks ◽  
James M. Isbell ◽  
Philip E. Williams ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Body Weight ◽  
Body Weight Loss ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Muscle Loss ◽  
Significant Component

Composition of weight loss in morbidly obese patients after gastric bypass

1981 ◽  
Vol 30 (5) ◽  
pp. 435-442 ◽  
Author(s):  
J.D. Palombo ◽  
C.J. Maletskos ◽  
R.V. Reinhold ◽  
E. Hayward ◽  
Joanne Wade ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Morbidly Obese ◽  
Obese Patients

scholarly journals Accuracy of prediction equations for calculating resting energy expenditure in morbidly obese patients

2012 ◽  
Vol 94 (2) ◽  
pp. 129-132 ◽  
Author(s):  
S Ullah ◽  
R Arsalani-Zadeh ◽  
J MacFie
Keyword(s):  
Body Mass Index ◽  
Weight Loss ◽  
Gastric Bypass ◽  
Indirect Calorimetry ◽  
Resting Energy Expenditure ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Prediction Equations ◽  
The Mean ◽  
Accuracy Of Prediction

INTRODUCTION The accuracy of prediction equations for estimating resting energy expenditure (REE) in morbidly obese patients is unclear. The aim of this study was to compare the REE measured using bedside indirect calorimetry with commonly used prediction equations. METHODS A total of 31 morbidly obese patients were studied. Pre-operative REE was measured with indirect calorimetry and compared with estimated REE using the Harris–Benedict and Schofield equations. All patients subsequently underwent a Roux-en-Y gastric bypass and measurements were repeated at six weeks and three months following surgery. RESULTS The mean age of the patients was 47 years. The mean pre-operative body mass index was 46kg/m2. The mean REE measured using indirect calorimetry was 1,980kcal/day. The estimated REE using the Harris–Benedict and Schofield formulae was 2,195 and 2,129kcal/day respectively. The equations overestimated REE by 10% and 7%. Body weight and body mass index reduced significantly following Roux-en-Y gastric bypass. There was no significant change in measured REE over the three-month period. After weight loss the difference between the estimated and measured REE reduced to 1–3%. CONCLUSIONS Prediction equations overestimate REE in morbidly obese patients. Their accuracy improved after surgery induced weight loss, confirming their validity for the normal weight population. Indirect calorimetry should be used in morbid obesity.

Weight loss and improvement of lipid profiles in morbidly obese patients after laparoscopic one-anastomosis gastric bypass: 2-year follow-up

2016 ◽  
Vol 31 (1) ◽  
pp. 416-421 ◽  
Author(s):  
Miguel A. Carbajo ◽  
Arlett Fong-Hirales ◽  
Enrique Luque-de-León ◽  
Juan Francisco Molina-Lopez ◽  
Javier Ortiz-de-Solórzano
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Lipid Profiles ◽  
One Anastomosis Gastric Bypass ◽  
Morbidly Obese ◽  
Obese Patients
Sign in / Sign up

Export Citation Format

Share Document