Dietary fish oil dose- and time-response effects on cardiac phospholipid fatty acid composition

Lipids ◽  
2004 ◽  
Vol 39 (10) ◽  
pp. 955-961 ◽  
Author(s):  
Alice J. Owen ◽  
Beata A. Peter-Przyborowska ◽  
Andrew J. Hoy ◽  
Peter L. McLennan
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Fish Oil ◽  
Acid Composition ◽  
Phospholipid Fatty Acid ◽  
Time Response ◽  
Phospholipid Fatty Acid Composition ◽  
Dietary Fish

scholarly journals The effect of increasing levels of dietary fish oil rich in eieosapentaenoic and docosahexaenoic acids on lymphocyte phospholipid fatty acid composition and cell-mediated immunity in the mouse

1993 ◽  
Vol 69 (2) ◽  
pp. 423-429 ◽  
Author(s):  
Alison Hinds ◽  
T. A. B. Sanders
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Fish Oil ◽  
Acid Composition ◽  
Phospholipid Fatty Acid ◽  
Cell Mediated Immunity ◽  
Phospholipid Fatty Acid Composition ◽  
Dietary Fish ◽  
Popliteal Lymph Node Assay ◽  
Docosahexaenoic Acids

The influence of increasing intakes of fish oil on spleen leucocyte phospholipid fatty acid composition and cell-mediated immunity was studied in the mouse using a popliteal lymph node assay technique. The immune response was suppressed by 160 g fish oil/kg diet, but not by lower doses. The proportion of 20: 5n-3 in spleen leucocyte phospholipid increased from 0.14 in the controls to 3.8, 7.2, 8.5 and 9.4% in the animals fed on 25, 50, 100 and 160 g fish oil/kg diet; the proportion of 22: 6n-3 increased from 5.1 in the controls to 12.1, 12.2, 12.8 and 12.9% respectively. It is concluded that moderate intakes of fish oil are not immunosuppressive.

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