In Silico Identification for α-Amino-ε-Caprolactam Racemases by Using Information on the Structure and Function Relationship

2015 ◽  
Vol 176 (5) ◽  
pp. 1303-1314 ◽  
Author(s):  
Wisarut Payoungkiattikun ◽  
Seiji Okazaki ◽  
Shogo Nakano ◽  
Atsutoshi Ina ◽  
Aran H-Kittikun ◽  
...  
Biochemistry ◽  
2011 ◽  
Vol 50 (39) ◽  
pp. 8352-8361 ◽  
Author(s):  
Alessia Belgi ◽  
Mohammed A. Hossain ◽  
Fazel Shabanpoor ◽  
Linda Chan ◽  
Suode Zhang ◽  
...  

2020 ◽  
Vol 129 (5) ◽  
pp. 1024-1032
Author(s):  
Hannah J. Thomas ◽  
Usaid Rana ◽  
Channa E. Marsh ◽  
Harrison T. Caddy ◽  
Lachlan J. Kelsey ◽  
...  

There is acknowledged variability in the Circle of Willis in the general population, yet the structure and function relationship of the cerebrovasculature is poorly understood. Using a combination of magnetic resonance imaging, high-resolution Doppler ultrasound, and computational fluid dynamic modeling, we show that monozygotic twins exhibit differences in cerebrovascular structure and function when exposed to physiological stimuli. These data suggest that the morphology, function, and health of cerebrovascular arteries are not primarily genetically determined.


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