Synthesis, Structure, and Anticancer Activity of Symmetrical and Non-symmetrical Silver(I)-N-Heterocyclic Carbene Complexes

2020 ◽  
Vol 191 (3) ◽  
pp. 1171-1189 ◽  
Author(s):  
Muhammad Atif ◽  
Haq Nawaz Bhatti ◽  
Rosenani A. Haque ◽  
Muhammad Adnan Iqbal ◽  
Mohammad B. Ahamed Khadeer ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Carbene Complexes

scholarly journals Synthesis and anticancer activity of silver(i)–N-heterocyclic carbene complexes derived from the natural xanthine products caffeine, theophylline and theobromine

2015 ◽  
Vol 44 (16) ◽  
pp. 7563-7569 ◽  
Author(s):  
Heba A. Mohamed ◽  
Benjamin R. M. Lake ◽  
Thomas Laing ◽  
Roger M. Phillips ◽  
Charlotte E. Willans
Keyword(s):  
Anticancer Activity ◽  
Carbene Complexes

Silver–N-heterocyclic carbene complexes derived from natural xanthine products have been prepared. Chemosensitivity studies indicate a correlation between cytotoxicity, ligand sterics and hydrophilicity.

Anthracenyl Functionalization of Half-Sandwich Carbene Complexes: In Vitro Anticancer Activity and Reactions with Biomolecules

2021 ◽  
Vol 60 (19) ◽  
pp. 14636-14644
Author(s):  
Betty Y. T. Lee ◽  
Matthew P. Sullivan ◽  
Ena Yano ◽  
Kelvin K. H. Tong ◽  
Muhammad Hanif ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Carbene Complexes ◽  
Half Sandwich

Synthesis, X-ray structures, spectroscopic analysis and anticancer activity of novel gold(I) carbene complexes

2014 ◽  
Vol 765 ◽  
pp. 68-79 ◽  
Author(s):  
Muhammad Altaf ◽  
M. Monim-ul-Mehboob ◽  
Adam A.A. Seliman ◽  
Anvarhusein A. Isab ◽  
Vikram Dhuna ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Spectroscopic Analysis ◽  
Carbene Complexes ◽  
X Ray

Anticancer Activity of Silver-N-Heterocyclic Carbene Complexes: Caspase-Independent Induction of Apoptosis via Mitochondrial Apoptosis-Inducing Factor (AIF)

ChemMedChem ◽  
2012 ◽  
Vol 7 (5) ◽  
pp. 805-814 ◽  
Author(s):  
Laure Eloy ◽  
Anne-Sophie Jarrousse ◽  
Marie-Laure Teyssot ◽  
Arnaud Gautier ◽  
Laurent Morel ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Mitochondrial Apoptosis ◽  
Carbene Complexes ◽  
Induction Of Apoptosis ◽  
Apoptosis Inducing Factor

scholarly journals Anticancer Activity of Ag(I) N-Heterocyclic Carbene Complexes Derived from 4,5-Dichloro-1H-Imidazole

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Doug A. Medvetz ◽  
Khadijah M. Hindi ◽  
Matthew J. Panzner ◽  
Andrew J. Ditto ◽  
Yang H. Yun ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Silver Complexes ◽  
Carbene Complexes ◽  
Human Cancer Cell Lines

A class of Ag(I) N-heterocyclic carbene silver complexes, 1–3, derived from 4,5-dichloro-1H-imidazole has been evaluated for their anticancer activity against the human cancer cell lines OVCAR-3 (ovarian), MB157 (breast), and Hela (cervical). Silver complexes 1–3 are active against the ovarian and breast cancer cell lines. A preliminary in vivo study shows 1 to be active against ovarian cancer in mice. The results obtained in these studies warrant further investigation of these compounds in vivo.

Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group

2015 ◽  
Vol 58 (15) ◽  
pp. 6283-6292 ◽  
Author(s):  
Julienne K. Muenzner ◽  
Tobias Rehm ◽  
Bernhard Biersack ◽  
Angela Casini ◽  
Inge A. M. de Graaf ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Dna Interaction ◽  
Carbene Complexes ◽  
Leaving Group

Coumarin-substituted 1,2,4-triazole-derived silver(i) and gold(i) complexes: synthesis, characterization and anticancer studies

2019 ◽  
Vol 43 (3) ◽  
pp. 1216-1229 ◽  
Author(s):  
Gautam Achar ◽  
Shahini C. R. ◽  
Siddappa A. Patil ◽  
Jan Grzegorz Małecki ◽  
Srinivasa Budagumpi
Keyword(s):  
Anticancer Activity ◽  
Cell Lines ◽  
Carbene Complexes ◽  
Ht 29 ◽  
Mcf 7 ◽  
Triazolium Salts

A series of coumarin-substituted 1,2,4-triazolium salts and their respective silver– and gold– N-heterocyclic carbene complexes have been reported. The complexes displayed promising anticancer activity with GI50 values of up to 0.354 μM and 8.5983 μM against MCF 7 and HT-29 cell lines, respectively.

Synthesis and anticancer activity of para-xylyl linked bis-benzimidazolium salts and respective Ag(I) N-heterocyclic carbene complexes

2012 ◽  
Vol 22 (5) ◽  
pp. 2455-2466 ◽  
Author(s):  
Muhammad Adnan Iqbal ◽  
Rosenani A. Haque ◽  
Mohamed B. Khadeer Ahamed ◽  
A. M. S. Abdul Majid ◽  
Sawsan S. Al-Rawi
Keyword(s):  
Anticancer Activity ◽  
Carbene Complexes ◽  
Benzimidazolium Salts

Phenoxide chelated Ir(iii) N-heterocyclic carbene complexes: synthesis, characterization, and evaluation of their in vitro anticancer activity

2018 ◽  
Vol 47 (39) ◽  
pp. 13781-13787 ◽  
Author(s):  
Yujiao Zhang ◽  
Shumiao Zhang ◽  
Zhenzhen Tian ◽  
Juanjuan Li ◽  
Zhishan Xu ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Carbene Complexes ◽  
Half Sandwich

This work demonstrated that the twelve novel half-sandwich IrIII–NHC complexes [(η5-Cpx)Ir(C^O)Cl] were synthesized and explored the mechanism of anticancer action.

Sign in / Sign up

Export Citation Format

Share Document