Donor Mesenchymal Stromal Cells (MSCs) Undergo Variable Cardiac Reprogramming in Vivo and Predominantly Co-Express Cardiac and Stromal Determinants after Experimental Acute Myocardial Infarction

2013 ◽  
Vol 10 (2) ◽  
pp. 304-315 ◽  
Author(s):  
Gustavo Yannarelli ◽  
James N. Tsoporis ◽  
Jean-Francois Desjardins ◽  
Xing Hua Wang ◽  
Ali Pourdjabbar ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells

Mesenchymal stromal cells mediate a switch to alternatively activated monocytes/macrophages after acute myocardial infarction

2011 ◽  
Vol 106 (6) ◽  
pp. 1299-1310 ◽  
Author(s):  
Victor Dayan ◽  
Gustavo Yannarelli ◽  
Filio Billia ◽  
Paola Filomeno ◽  
Xing-Hua Wang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Activated Monocytes ◽  
Alternatively Activated

scholarly journals Molecular Mechanisms Involved in Mesenchymal Stem Cell Migration to the Site of Acute Myocardial Infarction

2009 ◽  
Vol 2009 ◽  
pp. 1-8 ◽  
Author(s):  
Katarina Kollar ◽  
Matthew M. Cook ◽  
Kerry Atkinson ◽  
Gary Brooke
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Stromal Cells ◽  
Molecular Mechanisms ◽  
Current Knowledge ◽  
Multipotent Mesenchymal Stromal Cells ◽  
Myocardial Recovery ◽  
Stem Cell Migration ◽  
Intramuscular Delivery

Mesenchymal stem cells or multipotent mesenchymal stromal cells (both referred to as MSC) have been shown in some studies to have a beneficial effect on myocardial recovery after infarct. Current strategies for MSC delivery to heart involve intravenous, intraarterial, and intramuscular delivery. Different routes of MSC delivery and a lack of knowledge of the mechanisms that MSC utilise to migrate in vivo has most likely led to the marked variations in results that have been found. This review aims to summarise the current knowledge of MSC migratory mechanisms and looks to future methods of MSC manipulation prior to delivery in order to enhance MSC migration and engraftment.

Randomized, double-blind, phase I/II study of intravenous allogeneic mesenchymal stromal cells in acute myocardial infarction

Cytotherapy ◽  
2015 ◽  
Vol 17 (3) ◽  
pp. 250-261 ◽  
Author(s):  
Anoop Chullikana ◽  
Anish Sen Majumdar ◽  
Sanjay Gottipamula ◽  
Sagar Krishnamurthy ◽  
A. Sreenivas Kumar ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Phase I ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Double Blind

Dual-modular molecular imaging to trace transplanted bone mesenchymal stromal cells in an acute myocardial infarction model

Cytotherapy ◽  
2015 ◽  
Vol 17 (10) ◽  
pp. 1365-1373 ◽  
Author(s):  
Jian Cao ◽  
Xiao Li ◽  
Ning Chang ◽  
Yining Wang ◽  
Jing Lei ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Molecular Imaging ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells
Sign in / Sign up

Export Citation Format

Share Document