LIMD2 Is Overexpressed in BRAF V600E-Positive Papillary Thyroid Carcinomas and Matched Lymph Node Metastases

2018 ◽  
Vol 29 (3) ◽  
pp. 222-230 ◽  
Author(s):  
Maria José Carregosa Pinheiro dos Santos ◽  
André Uchimura Bastos ◽  
Vitor Rodrigues da Costa ◽  
Rosana Delcelo ◽  
Susan Chow Lindsey ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastases ◽  
Braf V600e ◽  
Papillary Thyroid ◽  
Thyroid Carcinomas ◽  
Node Metastases

scholarly journals Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases

Cancer ◽  
2008 ◽  
Vol 113 (5) ◽  
pp. 936-944 ◽  
Author(s):  
Monica Zerilli ◽  
Marco C. Amato ◽  
Anna Martorana ◽  
Daniela Cabibi ◽  
Johannes F. Coy ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastases ◽  
Papillary Thyroid ◽  
Thyroid Carcinomas ◽  
Node Metastases

scholarly journals BRAF V600E and lymph node metastases in papillary thyroid cancer

2020 ◽  
Vol 9 (10) ◽  
pp. 999-1008
Author(s):  
Pan Chen ◽  
Liqin Pan ◽  
Wensi Huang ◽  
Huijuan Feng ◽  
Wei Ouyang ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Papillary Thyroid Cancer ◽  
Lymph Node Metastases ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Papillary Thyroid ◽  
Metastatic Focus ◽  
Primary Tumors ◽  
Node Metastases

Objective To evaluate the relationship between the BRAF V600E mutation in lymph node metastasis (LNM) and its invasive characteristics in papillary thyroid cancer (PTC). Material and methods A total of 373 PTC patients were enrolled in this study conducted at Zhujiang Hospital of Southern Medical University between January 2017 and December 2018. PTCs with cervical lymph node metastases were verified pathohistologically, and primary tumors and LNM were examined for the BRAF V600E mutation. Patients were excluded from the study if the BRAF V600E mutation was examined only in primary tumors or only in LNM. Results Of the 373 patients examined, BRAF V600E mutation frequency in primary tumors was slightly higher than in LNM (81.5% vs 78.0%, P = 0.000), the intra-class correlation coefficient (ICC) was 0.865 (95% CI 0.835–0.890). The BRAF V600E mutation in both primary tumor and LNM negatively correlated with the size of the largest metastatic focus of LNM (Odds ratio, OR = 0.297, 95% CI 0.143–0.616, P = 0.001; OR = 0.242, 95% CI 0.119–0.492, P = 0.000, respectively). There was no relationship between BRAF V600E mutation in LNM and the number, extranodal extension or stage of LNM (P > 0.05). Conclusion The BRAF V600E mutation in LNM may not be related to the invasive characteristics of LNM in PTC.

Lymph Node Metastases in Thyroid Carcinomas: CT Diagnosis

2001 ◽  
Vol 45 (6) ◽  
pp. 581
Author(s):  
Ji Seon Joo ◽  
Hyung Jin Kim ◽  
Kyung Jin Kang ◽  
Young Kuk Cho ◽  
Myung Kwan Lim ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastases ◽  
Ct Diagnosis ◽  
Thyroid Carcinomas ◽  
Node Metastases
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