Successful treatment of gefitinib-induced acute interstitial pneumonitis with high-dose corticosteroid: a case report and literature review

2010 ◽  
Vol 28 (1) ◽  
pp. 79-82 ◽  
Author(s):  
Li-Chiao Kuo ◽  
Po-Chou Lin ◽  
Ko-Fan Wang ◽  
Mei-Kang Yuan ◽  
Shih-Chieh Chang
PEDIATRICS ◽  
1971 ◽  
Vol 48 (2) ◽  
pp. 338-339
Author(s):  
Edward J. Feroli ◽  
Gordon W. Mella ◽  
Frank A. Pedreira ◽  
Regis T. Storch ◽  
Howard P. Gutgesell

We read with interest the recent report, "Acute Airway Obstruction in Infectious Mononucleosis."1 Dr. Gutgesell appropriately has called attention to a serious complication of a usually benign disease. He mentions brief, high-dose corticosteroid therapy, tracheotomy, nasotracheal intubation, and IPPB as potential modes of therapy. The following case report suggests an additional therapeutic modality in the management of these patients. A 4-year-old girl was admitted to a community hospital in acute respiratory distress associated with suspected infectious mononucleosis.


1992 ◽  
Vol 41 (1) ◽  
pp. 69-69 ◽  
Author(s):  
Michihiro Toyoshige ◽  
Yuzuru Zaitsu ◽  
Koichiro Okafuji ◽  
Yasushi Inoue ◽  
Yukio Hiroshige ◽  
...  

2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Ahmed Alsolami ◽  
Kevin Shiley

Abstract A case of influenza-associated acute necrotizing encephalitis (ANE) is described in an otherwise healthy adult. The patient was treated successfully with a combination of high-dose methylprednisolone and high-dose oseltamivir. The patient relapsed after discontinuing 150 mg twice daily oseltamivir but quickly improved and eventually recovered after reinitiation of high-dose oseltamivir for an additional 2 weeks. The clinical presentation, pathogenesis, and treatment of influenza-associated ANE is reviewed. The use of high-dose oseltamivir in combination with methylprednisolone may offer additional therapeutic benefit for this rare and poorly understood complication of influenza infection.


2017 ◽  
Vol 12 (2) ◽  
pp. e11-e13 ◽  
Author(s):  
Kazutaka Fujita ◽  
Yuko Morishima ◽  
Yuka Aida ◽  
Yoshiya Tsunoda ◽  
Norihito Hida ◽  
...  

Author(s):  
Hamed Cheraghmakani ◽  
Reza Jafari ◽  
Elahe Karimpour-razkenari ◽  
monireh Ghazaeian

A 20-year-old girl referred with vision loss upon closantel use. Plasma exchange and high-dose corticosteroid pulse therapy were administered. A 2.5-year follow-up showed improved vision and increased layer thickness of the peripheral nerve fiber. Early treatment with plasma exchange and high-dose corticosteroid therapy can be beneficial to reverse closantel toxicity.


2006 ◽  
Vol 92 (6) ◽  
pp. 542-544 ◽  
Author(s):  
Karl Leimgruber ◽  
Rosa Negro ◽  
Susanne Baier ◽  
Bernadetta Moser ◽  
Gerhard Resch ◽  
...  

Taxanes are widely used chemotherapeutic agents with the potential to induce pulmonary injury through a variety of mechanisms. Patients receiving these agents are at risk of acute or subacute pulmonary damage. The case is presented of a 72-year-old man with hormone-refractory prostate cancer and weekly administration of 30 mg/m2 docetaxel who developed subacute interstitial pneumonitis-related pulmonary fibrosis after seven doses and died despite mechanical ventilation and high-dose corticosteroid treatment. Even though only a few cases of this adverse event have been reported in the literature, severe docetaxel-induced pulmonary toxicity needs to be considered in the differential diagnosis when such patients present with respiratory symptoms.


2015 ◽  
Vol 30 (9) ◽  
pp. 1506-1512.e5 ◽  
Author(s):  
Michael A. Mont ◽  
Robert Pivec ◽  
Samik Banerjee ◽  
Kimona Issa ◽  
Randa K. Elmallah ◽  
...  

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