miR-200c modulates ovarian cancer cell metastasis potential by targeting zinc finger E-box-binding homeobox 2 (ZEB2) expression

2014 ◽  
Vol 31 (8) ◽  
Author(s):  
Yan-ming Lu ◽  
Chao Shang ◽  
Yang-ling Ou ◽  
Duo Yin ◽  
Yi-Ning Li ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Zinc Finger ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Cell Metastasis ◽  
E Box ◽  
Zeb2 Expression

S100A7 Regulates Ovarian Cancer Cell Metastasis and Chemoresistance Through MAPK Signaling and Is Targeted by miR-330-5p

2018 ◽  
Vol 37 (5) ◽  
pp. 491-500 ◽  
Author(s):  
Mei Lin ◽  
Bairong Xia ◽  
Ling Qin ◽  
Hong Chen ◽  
Ge Lou
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Mapk Signaling ◽  
Cell Metastasis

scholarly journals Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Bynthia M. Anose ◽  
Michel M. Sanders
Keyword(s):  
Prostate Cancer ◽  
Transcription Factor ◽  
Signaling Pathways ◽  
Zinc Finger ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Prostate Cancer Cell Line ◽  
Homeodomain Proteins ◽  
Cell Metastasis ◽  
E Box

The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal transitions (EMTs). ZEB1 (also known as δEF1, zfhx1a, TCF8, and Zfhep) plays a key role in regulating such diverse processes as T-cell development, skeletal patterning, reproduction, and cancer cell metastasis. However, the factors that regulate its expression and consequently the signaling pathways in which ZEB1 participates are poorly defined. Because it is induced by estrogen and progesterone and is high in prostate cancer, we investigated whethertcf8, which encodes ZEB1, is regulated by androgen. Data herein demonstrate thattcf8is induced by dihydrotestosterone (DHT) in the human PC-3/AR prostate cancer cell line and that this induction is mediated by two androgen response elements (AREs). These results demonstrate that ZEB1 is an intermediary in androgen signaling pathways.

scholarly journals The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin

2008 ◽  
Vol 118 (4) ◽  
pp. 1367-1379 ◽  
Author(s):  
Hilary A. Kenny ◽  
Swayamjot Kaur ◽  
Lisa M. Coussens ◽  
Ernst Lengyel
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Cell Metastasis

TWEAK promotes ovarian cancer cell metastasis via NF-κB pathway activation and VEGF expression

2009 ◽  
Vol 283 (2) ◽  
pp. 159-167 ◽  
Author(s):  
Lan Dai ◽  
Liying Gu ◽  
Chuanwei Ding ◽  
Lihua Qiu ◽  
Wen Di
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Vegf Expression ◽  
Pathway Activation ◽  
Cell Metastasis

Inhibition of ovarian cancer cell metastasis by a fusion polypeptide Tat-ELP

2009 ◽  
Vol 26 (3) ◽  
pp. 251-260 ◽  
Author(s):  
Iqbal Massodi ◽  
Gene L. Bidwell ◽  
Aisha Davis ◽  
Abby Tausend ◽  
Kimberly Credit ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Cell Metastasis

scholarly journals KY Hemp‐induced Modulation of Ovarian Cancer Cell Metastasis

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Sara Biela ◽  
Annie Wang ◽  
Wasana K. Sumanasekera
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Cell Metastasis
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