Significance of a frozen section analysis of the ureteral margin in bladder cancer patients treated with radical cystectomy and neoadjuvant chemotherapy

2017 ◽  
Vol 34 (12) ◽  
Author(s):  
Kyohei Hakozaki ◽  
Eiji Kikuchi ◽  
Keishiro Fukumoto ◽  
Suguru Shirotake ◽  
Yasumasa Miyazaki ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Radical Cystectomy ◽  
Frozen Section ◽  
Frozen Section Analysis ◽  
Section Analysis

Intraoperative Frozen Section Analysis of Sentinel Lymph Node in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy

2008 ◽  
Vol 15 (6) ◽  
pp. 1717-1722 ◽  
Author(s):  
Kenzo Shimazu ◽  
Yasuhiro Tamaki ◽  
Tetsuya Taguchi ◽  
Fumine Tsukamoto ◽  
Tsutomu Kasugai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Frozen Section ◽  
Breast Cancer Patients ◽  
Intraoperative Frozen Section ◽  
Frozen Section Analysis ◽  
Section Analysis

The value of frozen-section analysis of ureteric margins on surgical decision-making in patients undergoing radical cystectomy for bladder cancer

2007 ◽  
Vol 99 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Yasser Osman ◽  
Nasr El-Tabey ◽  
Mohamed Abdel-Latif ◽  
Ahmed Mosbah ◽  
Noheir Moustafa ◽  
...  
Keyword(s):  
Decision Making ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Frozen Section ◽  
Surgical Decision ◽  
Frozen Section Analysis ◽  
Surgical Decision Making ◽  
Section Analysis

scholarly journals Utility of Routine Intraoperative Ureteral Frozen Section Analysis at Radical Cystectomy: Outcomes from a Regional Australian Center

2018 ◽  
Vol 12 (2) ◽  
pp. 70-73 ◽  
Author(s):  
Joanne Tang ◽  
Weranja Ranasinghe ◽  
Janice Cheng ◽  
Sabiena Van Es ◽  
Mike Monsour ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Cox Regression ◽  
Frozen Section ◽  
Fold Increase ◽  
Tumor Stage ◽  
Clinical Staging ◽  
Cox Regression Analysis ◽  
Frozen Section Analysis ◽  
Section Analysis

Introduction: The objective of this study was to look at the usefulness and cost effectiveness of intraoperative frozen section analysis (FSA) of the ureters at the time of radical cystectomy. Methods: Pathology notes of patients undergoing radical cystectomy for primary bladder cancer between the years 2000-2015 at our institution were reviewed. Results: A total of 196 ureteric specimens from 98 patients were reviewed. Of the 98 patients, 9% (n = 9) had positive ureteric margins, of which all were ≥ T2, with 44% (4 of 9) being T = 4. In all cases of positive FSA, preoperative clinical staging was ≥ T2. In cases where cancer staging was upgraded post-cystectomy, there were no cases of positive FSA. After adjusting for tumor stage in ≥ T2a, using Cox regression analysis, positive frozen section was associated with a 4.2 fold increase in overall mortality (95%CI 1.3-13.8; p = 0.02). Cost associated with FSA was AU$1,351.90 to obtain 1 positive result. Conclusion: Patients with positive ureteric FSA are at higher risk of mortality post cystectomy, despite excision to negative tissue. However, FSA of the distal ureters at cystectomy were unlikely to be positive unless the bladder cancer stage was ≥ T2. Hence, routine ureteric FSA may not be necessary in patients undergoing cystectomy for non-muscle invasive bladder tumors.

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