scholarly journals Evaluation of aldehyde dehydrogenase 1 and transcription factors in both primary breast cancer and axillary lymph node metastases as a prognostic factor

Breast Cancer ◽  
2015 ◽  
Vol 23 (3) ◽  
pp. 437-444 ◽  
Author(s):  
Maiko Ito ◽  
Tadahiko Shien ◽  
Masako Omori ◽  
Taeko Mizoo ◽  
Takayuki Iwamoto ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Transcription Factors ◽  
Lymph Node ◽  
Prognostic Factor ◽  
Aldehyde Dehydrogenase ◽  
Lymph Node Metastases ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases

Aldehyde dehydrogenase 1-positive cells in axillary lymph node metastases after chemotherapy as a prognostic factor in patients with lymph node-positive breast cancer

Cancer ◽  
2011 ◽  
Vol 118 (16) ◽  
pp. 3899-3910 ◽  
Author(s):  
Masahiro Sakakibara ◽  
Toshihiko Fujimori ◽  
Tetsutaro Miyoshi ◽  
Takeshi Nagashima ◽  
Hiroshi Fujimoto ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Prognostic Factor ◽  
Aldehyde Dehydrogenase ◽  
Lymph Node Metastases ◽  
Axillary Lymph ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases ◽  
Lymph Node Positive ◽  
Positive Breast Cancer

scholarly journals Aldehyde dehydrogenase 1 (ALDH1) immunostaining in axillary lymph node metastases is an independent prognostic factor in ALDH1-positive breast cancer

2021 ◽  
Vol 49 (10) ◽  
pp. 030006052110472
Author(s):  
Xin Guan ◽  
Yi Dong ◽  
Zhimin Fan ◽  
Yue Zhan ◽  
Xinpeng Xie ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Aldehyde Dehydrogenase ◽  
Lymph Node Metastases ◽  
Axillary Lymph Node ◽  
Poor Prognosis ◽  
Axillary Lymph ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases

Objective To determine whether aldehyde dehydrogenase 1 (ALDH1) immunostaining in axillary lymph node metastases in patients with breast cancer is associated with poor clinical prognosis. Methods This retrospective study reviewed data from the medical records of patients with immunohistochemistry-confirmed invasive ductal carcinoma (IDC) and 1–3 metastatic lymph nodes in the ipsilateral axilla between December 2012 and July 2015. The association between ALDH1 immunostaining in axillary lymph node metastases and clinical parameters and prognosis was analysed using χ2-test, Kaplan–Meier survival analysis, univariate and multivariate Cox regression analyses. Results A total of 229 patients with IDC were enrolled in the study. The median follow-up was 61 months (range, 20–89 months). Patients with ALDH1-positive axillary lymph node metastases had significantly shorter relapse-free survival and overall survival compared with those with ALDH1-negative axillary lymph node metastases. ALDH1 immunostaining in axillary lymph node metastases was a significant predictor of poor prognosis in univariate and multivariate analyses. Conclusion This large study with long-term follow-up suggests that ALDH1 immunostaining in axillary lymph node metastases is an independent predictor of poor prognosis in patients with breast cancer. The clinical relevance of this finding should be confirmed in further well-designed prospective studies.

Predictors of axillary lymph node metastases in patients with impalpable breast cancer

The Breast ◽  
1997 ◽  
Vol 6 (3) ◽  
pp. 143-145 ◽  
Author(s):  
C.I. Perre ◽  
V.C.M. Koot ◽  
E.P.A. van der Heijden ◽  
V. Vossen ◽  
J.R. de Jong ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases

The Importance of Extracapsular Extension of Axillary Lymph Node Metastases in Breast Cancer

2004 ◽  
Vol 90 (1) ◽  
pp. 107-111 ◽  
Author(s):  
Görken Bilkay İlknur ◽  
Alanyali Hilmi ◽  
Canda Tülay ◽  
Çetinayak Oguz ◽  
Sengiz Selma ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Extracapsular Extension ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases

Predictors for extensive nodal involvement in breast cancer patients with axillary lymph node metastases

The Breast ◽  
2016 ◽  
Vol 27 ◽  
pp. 175-181 ◽  
Author(s):  
N.C. Verheuvel ◽  
H.W.A. Ooms ◽  
V.C.G. Tjan-Heijnen ◽  
R.M.H. Roumen ◽  
A.C. Voogd
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Lymph Node Metastases ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Nodal Involvement ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases

Axillary lymph node metastases in breast cancer: preoperative detection with US.

Radiology ◽  
1986 ◽  
Vol 158 (2) ◽  
pp. 325-326 ◽  
Author(s):  
J N Bruneton ◽  
E Caramella ◽  
M Héry ◽  
D Aubanel ◽  
J J Manzino ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases
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