Role of dietary fat on obesity-related postmenopausal breast cancer: insights from mouse models and methodological considerations

Breast Cancer ◽  
2021 ◽  
Author(s):  
Pei Yee Tan ◽  
Kim Tiu Teng
Bone Reports ◽  
2021 ◽  
Vol 14 ◽  
pp. 100900
Author(s):  
Evi Gkikopoulou ◽  
Anthi Kolokotroni ◽  
Vagelis Rinotas ◽  
Melina Dragolia ◽  
Vasileios Ntafis ◽  
...  

2012 ◽  
Vol 48 ◽  
pp. S184-S185
Author(s):  
S. Krenn-Pilko ◽  
G. Hofmann ◽  
W. Renner ◽  
A. Gerger ◽  
E.M. Thurner ◽  
...  

2014 ◽  
Vol 39 (6) ◽  
pp. 699-706 ◽  
Author(s):  
Breanne M. Anderson ◽  
Mira B. MacLennan ◽  
Lyn M. Hillyer ◽  
David W.L. Ma

There is growing evidence that early developmental periods may importantly influence future breast cancer risk. Also, there is great interest in the role of dietary fat in breast cancer risk, but the role of dietary fat during pubertal mammary gland development remains poorly understood. This study investigated the effect of n-3 polyunsaturated fatty acids (PUFA) using complementary dietary and genetic approaches to examine the effect of lifelong exposure of n-3 PUFA or n-6 PUFA (control) on mammary gland development and fatty acid composition. n-3 PUFA from both diet and genetics were enriched in mammary glands as early as 3 weeks of age. Parameters related to mammary gland development, including number of terminal end buds (TEB), percent coverage of ductal tree, and infiltration of TEB, were influenced by n-3 PUFA at 3 and 4 weeks of age. Overall, findings suggest that n-3 PUFA incorporation into the mammary gland early in life plays a role in the morphological development of the mammary gland during puberty.


2008 ◽  
Vol 26 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Anne C. M. Thiébaut ◽  
Victor Kipnis ◽  
Arthur Schatzkin ◽  
Laurence S. Freedman

1992 ◽  
Vol 84 (21) ◽  
pp. 1666-1667 ◽  
Author(s):  
M. C. PIKE ◽  
L. BERNSTEIN ◽  
R. K. PETERS

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