Oncologic and clinical outcomes in pelvic primary bone sarcomas treated with limb salvage surgery

2015 ◽  
Vol 99 (3) ◽  
pp. 237-242 ◽  
Author(s):  
G. L. Farfalli ◽  
J. I. Albergo ◽  
L. E. Ritacco ◽  
M. A. Ayerza ◽  
D. L. Muscolo ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Limb Salvage ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Bone Sarcomas ◽  
Primary Bone

Limb salvage surgery for primary bone sarcoma of the lower extremities: Long-term consequences of endoprosthetic reconstructions

1998 ◽  
Vol 5 (5) ◽  
pp. 423-436 ◽  
Author(s):  
S. John Ham ◽  
Heimen Schraffordt Koops ◽  
René P. H. Veth ◽  
Jim R. van Horn ◽  
Willemina M. Molenaar ◽  
...  
Keyword(s):  
Limb Salvage ◽  
Salvage Surgery ◽  
Lower Extremities ◽  
Bone Sarcoma ◽  
Limb Salvage Surgery ◽  
Primary Bone Sarcoma ◽  
Primary Bone ◽  
Long Term Consequences

Clinical outcomes of limb salvage surgery with postoperative intensity-modulated radiation therapy for soft-tissue sarcoma and metastasis

2018 ◽  
Vol 55 (2) ◽  
pp. 176
Author(s):  
Katsuhisa Kawanami ◽  
Toshihiro Matsuo ◽  
Shintaro Yuki ◽  
Shoji Shimose ◽  
Ryosuke Takahashi ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Clinical Outcomes ◽  
Limb Salvage ◽  
Salvage Surgery ◽  
Intensity Modulated Radiation Therapy ◽  
Limb Salvage Surgery ◽  
Intensity Modulated

scholarly journals Comparison of MRI and Histopathology with regard to Intramedullary Extent of Disease in Bone Sarcomas

Sarcoma ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Ashish Gulia ◽  
Ajay Puri ◽  
T. S. Subi ◽  
Srinath M. Gupta ◽  
S. L. Juvekar ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Correlation Analysis ◽  
Limb Salvage ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Bone Sarcomas ◽  
The Mean ◽  
Extent Of Disease

In today’s era, limb salvage surgery is the procedure of choice and current standard of care in appropriately selected patients of bone sarcomas. For adequate oncologic clearance, preoperative evaluation of the extent of tumor is mandatory. The present study was done to compare measurements of bone sarcomas (osteosarcoma, Ewing’s sarcoma, and chondrosarcoma) as determined by magnetic resonance imaging (MRI) with the histopathological extent seen on resected specimens. We prospectively evaluated 100 consecutive patients with a diagnosis of bone sarcoma who underwent limb salvage surgery between May 2014 and December 2014. The maximum longitudinal (cranio-caudal) dimension of tumor on the noncontrast T1-WI sequence of MRI (irrespective of whether it was pre/postchemotherapy) was compared with the gross dimensions of the tumor on histopathology. The arithmetic mean difference, Wilcoxon signed-rank test, and Spearman’s correlation analysis were used to test the differences and correlation between groups. Mean tumor size on MRI based on the largest extent on MRI was 12.1 ± 4.85 cm (mean ± standard deviation), while it was 10.77 ± 4.6 cm (mean ± standard deviation) on histopathology. In 79 cases, MRI overestimated the extent of disease; the mean was 1.79 cm with a standard deviation of 1.56 cm. When the disease extent was underestimated on MRI (13 cases), the mean was 0.58 cm with a standard deviation of 0.43 cm. In 8 cases (osteosarcoma (7), Ewing’s sarcoma (1)), MRI measurement was equal to histopathology. The Spearman correlation analysis showed a high correlation of tumor length on histopathology with the MRI for all patients (R = 0.948, P<0.0001). We thus conclude that MRI is accurate in delineating the extent of bone sarcomas. A margin of 2 cm from the maximum tumor extent is adequate to ensure appropriate surgical resection.

Quality of life following limb-salvage surgery for bone sarcomas

2011 ◽  
Vol 11 (1) ◽  
pp. 59-73 ◽  
Author(s):  
Pietro Ruggieri ◽  
Andreas F Mavrogenis ◽  
Mario Mercuri
Keyword(s):  
Quality Of Life ◽  
Limb Salvage ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Bone Sarcomas

Is limb salvage surgery safe for bone sarcomas identified after a previous surgical procedure?

2014 ◽  
Vol 96-B (5) ◽  
pp. 665-672 ◽  
Author(s):  
C. L. Gaston ◽  
T. Nakamura ◽  
K. Reddy ◽  
A. Abudu ◽  
S. Carter ◽  
...  
Keyword(s):  
Limb Salvage ◽  
Surgical Procedure ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Bone Sarcomas

scholarly journals THE APPLICATION OF EXPANDABLE ENDOPROSTHETIC RECONSTRUCTION FOR LIMB SALVAGE SURGERY IN THE SKELETALLY IMMATURE PATIENTS

2001 ◽  
Vol 13 (03) ◽  
pp. 141-147 ◽  
Author(s):  
RONG-SEN YANG
Keyword(s):  
Limb Salvage ◽  
Salvage Surgery ◽  
Limb Length Discrepancy ◽  
Limb Length ◽  
Limb Salvage Surgery ◽  
Skeletally Immature ◽  
Endoprosthetic Reconstruction ◽  
Term Survival ◽  
Length Discrepancy ◽  
Primary Bone

The development of new image techniques enables the early detection of bone tumors in the extremities in the past two decades. In addition, new advance of adjuvant therapy improves the long-term survival of patients with primary bone malignancies. Since the primary bone malignancy frequently occurs at the metaphysis of long bones of pediatric patients in the first and second decade, many patients have to face the late problems of limb length discrepancy after the limb salvage operation. Since the inevitable limb length discrepancy will interfere the functional outcomes and cosmetic appearance, the reconstruction of limb defect after limb salvage remains a challenge. Several options of reconstruction are available for these patients, including resection arthrodesis, rotationplasty, osteochondral allograft reconstruction, and endoprosthetic reconstruction. All these methods are difficult to address the limb length discrepancy. The development of expandable endoprosthetic reconstruction makes limb-salvage surgery feasible in the skeletally immature and provides another choice of solution. This article presents the current status of custom-expandable endoprosthetic reconstruction in the skeletally immature patients after wide resection of primary bone malignancies in the extremity. The surgical options, complications and functional results will be emphasized. Basically these expandable endoprostheses can be classified according to the expansion design. Recent reports demonstrated that the results of expandable prosthesis in the growing children are rather acceptable. Some patients can regain the equal limb length after expansion of the prosthesis. However these patients have to take several expansion procedures for the equality of limb length during the growing period. A rather high complication rate of either endoprosthesis-related or disease-associated still needs to be settled in the near future. These include mechanical failure of the expansion mechanism, extensive metallosis, aseptic loosening, fatigue fracture, flexion contracture, local recurrence, delayed wound healing, fat embolism, local overgrowth of counterpart bone, nerve palsy, infection, and bone fracture. Some patients even require an amputation even after expandable endoprosthesis reconstruction because of difficult reconstruction or severe functional impairment. However, with regard to difficult rehabilitation for patients under 8 years, amputation or alternative options need to be considered. A comprehensive discussion with the parents and patient about the detailed treatment protocol is needed before performing reconstruction using expandable endoprosthesis.

scholarly journals Limb salvage surgery in primary bone tumors

1997 ◽  
Vol 68 (sup275) ◽  
pp. 101-102
Author(s):  
Stavros Voutzoulias ◽  
Nikolaos Demetzis ◽  
Ioannis Kyriazoglou ◽  
Dimitris Lekkas
Keyword(s):  
Limb Salvage ◽  
Bone Tumors ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Primary Bone Tumors ◽  
Primary Bone

scholarly journals 3D-Printed Connector for Revision Limb Salvage Surgery in Long Bones Previously Using Customized Implants

Metals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 707
Author(s):  
Jong-Woong Park ◽  
Hyun-Guy Kang ◽  
June-Hyuk Kim ◽  
Han-Soo Kim
Keyword(s):  
Limb Salvage ◽  
Salvage Surgery ◽  
Revisional Surgery ◽  
Limb Salvage Surgery ◽  
Musculoskeletal Tumor ◽  
Musculoskeletal Tumor Society ◽  
Proximal Ulna ◽  
Custom Made ◽  
Orthopedic Oncology ◽  
3D Printed

In orthopedic oncology, revisional surgery due to mechanical failure or local recurrence is not uncommon following limb salvage surgery using an endoprosthesis. However, due to the lack of clinical experience in limb salvage surgery using 3D-printed custom-made implants, there have been no reports of revision limb salvage surgery using a 3D-printed implant. Herein, we present two cases of representative revision limb salvage surgeries that utilized another 3D-printed custom-made implant while retaining the previous 3D-printed custom-made implant. A 3D-printed connector implant was used to connect the previous 3D-printed implant to the proximal ulna of a 40-year-old man and to the femur of a 69-year-old woman. The connector bodies for the two junctions of the previous implant and the remaining host bone were designed for the most functional position or angle by twisting or tilting. Using the previous 3D-printed implant as a taper, the 3D-printed connector was used to encase the outside of the previous implant. The gap between the previous implant and the new one was subsequently filled with bone cement. For both the upper and lower extremities, the 3D-printed connector showed stable reconstruction and excellent functional outcomes (Musculoskeletal Tumor Society scores of 87% and 100%, respectively) in the short-term follow-up. To retain the previous 3D-printed implant during revision limb salvage surgery, an additional 3D-printed implant may be a feasible surgical option.

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