Anti-inflammatory effect of sweetfish-derived protein and its enzymatic hydrolysate on LPS-induced RAW264.7 cells via inhibition of NF-κB transcription

2012 ◽  
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pp. 381-390 ◽  
Author(s):  
Nak-Yun Sung ◽  
Pil-Moon Jung ◽  
Minchul Yoon ◽  
Jeong-Soo Kim ◽  
Jong-il Choi ◽  
...  
2012 ◽  
Vol 41 (11) ◽  
pp. 1645-1648 ◽  
Author(s):  
Chang-Hyun Kim ◽  
Mi-Ai Lee ◽  
Tae-Woon Kim ◽  
Ja Young Jang ◽  
Hyun Ju Kim

2018 ◽  
Vol 28 (10) ◽  
pp. 1635-1644 ◽  
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Chaiwat Monmai ◽  
Seok Hyeon Go ◽  
Il-shik Shin ◽  
SangGuan You ◽  
Dae-ok Kim ◽  
...  

2014 ◽  
Vol 27 (3) ◽  
pp. 209-214 ◽  
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Gwang Hun Park ◽  
Jae Ho Park ◽  
Hyun Ji Eo ◽  
Hun Min Song ◽  
Man Hyo Lee ◽  
...  

2017 ◽  
Vol 45 (2) ◽  
pp. 110-117 ◽  
Author(s):  
Min-Ji Kim ◽  
Min-Ju Kim ◽  
Koth Bong Woo Ri Kim ◽  
Sun Hee Park ◽  
Hyeun Deok Choi ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Yi Xin ◽  
Qin Yuan ◽  
Chaoqi Liu ◽  
Changcheng Zhang ◽  
Ding Yuan

Abstract It has been demonstrated that Chikusetsusaponin IVa (CsIVa) possesses abundant biological activities. Herein, using LPS to establish acute inflammation model of mouse liver and cell line inflammation model, we investigated whether miR-155/GSK-3β regulated NF-κB signaling pathway, and CsIVa exerted anti-inflammatory effects by regulating miR-155/GSK-3β signaling pathway. Our results showed that LPS induced high expression of miR-155 and miR-155 promoted macrophage activation through GSK-3β. In addition, CsIVa inhibited inflammatory responses in LPS-induced mouse liver and RAW264.7 cells. Furthermore, we demonstrated that CsIVa improved the inflammatory response in LPS-induced RAW264.7 cells by inhibiting miR-155, increasing GSK-3β expression, and inhibiting NF-κB signaling pathway. In conclusion, our study reveals that CsIVa suppresses LPS-triggered immune response by miR-155/GSK-3β-NF-κB signaling pathway.


2018 ◽  
Vol 116 ◽  
pp. 327-334 ◽  
Author(s):  
Su Bin Park ◽  
Gwang Hun Park ◽  
Yurry Um ◽  
Ha Na Kim ◽  
Hun Min Song ◽  
...  

2020 ◽  
Vol 23 (11) ◽  
pp. 1183-1191
Author(s):  
Kyung-A Hwang ◽  
Wan Heo ◽  
Hye-Jeong Hwang ◽  
Bok Kyung Han ◽  
Myoung Chong Song ◽  
...  

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