l(+)-Lactic Acid Production by Immobilized Lactobacillus casei Using Low Cost Agro-Industrial Waste as Carbon and Nitrogen Sources

2017 ◽  
Vol 10 (5) ◽  
pp. 1119-1129 ◽  
Author(s):  
Avinash Thakur ◽  
Parmjit Singh Panesar ◽  
Manohar Singh Saini
2011 ◽  
Vol 164 (7) ◽  
pp. 1160-1171 ◽  
Author(s):  
Luciana Fontes Coelho ◽  
Cristian J. Bolner de Lima ◽  
Marcela Piassi Bernardo ◽  
Jonas Contiero

2018 ◽  
Vol 36 (No. 2) ◽  
pp. 146-153 ◽  
Author(s):  
Gharwalová Lucia ◽  
Paulová Leona ◽  
Patáková Petra ◽  
Branská Barbora ◽  
Melzoch Karel

Biotechnological production of lactic acid has experienced a boom that is hindered only by the lack of low-cost, abundant material that might be used as a substrate for lactic acid bacteria. Such material should contain not only carbon but also complex nitrogen sources, amino acids and vitamins necessary for the balanced growth of the bacteria. Here, for the first time, a combination of hydrolysates of wheat straw and chicken feathers was used as a complete waste cultivation medium for lactic acid production. It was shown to be a promising substrate for lactic acid production, reducing the medium price by 73% compared with MRS broth, providing more than 98% lactic acid yield and high productivity (2.28 ± 0.68 g/l/h) in a fed-batch process using Lactobacillus reuterii LHR14.


Fermentation ◽  
2020 ◽  
Vol 6 (4) ◽  
pp. 97 ◽  
Author(s):  
Susan Krull ◽  
Silvia Brock ◽  
Ulf Prüße ◽  
Anja Kuenz

Lactic acid is a building block for polylactic acid, which is one of the most promising polymers based on renewable resources and is used mainly in packaging industry. This bio-based polymer is biodegradable and provides an ecological and economical alternative to petrochemical plastics. The largest cost blocks of biotechnological lactic acid production, accounting for up to 38% of the total costs, are substrate and nutrient sources, such as peptone, meat, and yeast extract. Based on a systematic analysis of nutritional requirements, the substitution of yeast extract by low-cost protein-rich agricultural hydrolysates was estimated for the production of l-lactic acid with Lactobacillus casei. Cultivations in 24-well microtiter plates enabled analysis of nutrient requirements and the usage of various hydrolysates with a high parallel throughput and repeated sampling. Rapeseed meal (RM) and distillers’ dried grains with solubles (DDGS) were tested as low-cost protein-rich agricultural residues. By using chemically or enzymatically hydrolyzed rapeseed meal or DDGS, 70% of the nutrient sources was replaced in the fermentation process at identical productivity and product yields. All in all, the total costs of l-lactic acid production with Lactobacillus casei could potentially be reduced by up to 23%.


2005 ◽  
Vol 27 (21) ◽  
pp. 1685-1688 ◽  
Author(s):  
Pappy John Rojan ◽  
Kesavan Madhavan Nampoothiri ◽  
Athira Syamaprasad Nair ◽  
Ashok Pandey

2019 ◽  
Vol 57 (3) ◽  
pp. 915-926 ◽  
Author(s):  
Rengesh Balakrishnan ◽  
Subbi Rami Reddy Tadi ◽  
Allampalli Satya Sai Pavan ◽  
Senthilkumar Sivaprakasam ◽  
Shyamkumar Rajaram

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