In vitro characterization of nanofibrous PLGA/gelatin/hydroxyapatite composite for bone tissue engineering

2010 ◽  
Vol 18 (12) ◽  
pp. 1195-1202 ◽  
Author(s):  
Jung Bok Lee ◽  
Sung Eun Kim ◽  
Dong Nyoung Heo ◽  
Il Keun Kwon ◽  
Byung-Joon Choi
2014 ◽  
Vol 29 (8) ◽  
pp. 1075-1085 ◽  
Author(s):  
Akanksha Kanitkar ◽  
Cong Chen ◽  
Mollie Smoak ◽  
Katie Hogan ◽  
Thomas Scherr ◽  
...  

2019 ◽  
Vol 29 (5) ◽  
pp. 984-996 ◽  
Author(s):  
Hamid Reza BAKHSHESHI-RAD ◽  
Ehsan DAYAGHI ◽  
Ahmad Fauzi ISMAIL ◽  
Madzlan AZIZ ◽  
Ali AKHAVAN-FARID ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 110557-110565 ◽  
Author(s):  
Yinxian Yu ◽  
Sha Hua ◽  
Mengkai Yang ◽  
Zeze Fu ◽  
Songsong Teng ◽  
...  

A composite scaffold was fabricated with a method involving both electrospinning and 3D printing to give microscale pores and good mechanical properties. Biocompatibility and cell infiltration on the scaffold was evaluated by an in vitro study.


ACS Omega ◽  
2021 ◽  
Vol 6 (6) ◽  
pp. 4335-4346
Author(s):  
Muhammad Umar Aslam Khan ◽  
Saiful Izwan Abd Razak ◽  
Hassan Mehboob ◽  
Mohammed Rafiq Abdul Kadir ◽  
T. Joseph Sahaya Anand ◽  
...  

2007 ◽  
Vol 342-343 ◽  
pp. 369-372 ◽  
Author(s):  
S.J. Heo ◽  
S.E. Kim ◽  
Yong Taek Hyun ◽  
D.H. Kim ◽  
Hyang Mi Lee ◽  
...  

This study evaluated the potential of the PCL (poly -caprolactone)/HA(Hydroxyapatite) composite materials as a scaffold for bone regeneration. For this, we fabricated scaffolds utilizing salt leaching method. The PCL/HA composite scaffolds were prepared with various HA contents (20wt%, 40wt%, 60 wt %). To ensure the potential for the scaffolds, porosity tests were conducted along with SEM observations. The porosity decreased with the increase of the contents of HA particles. The porosity of the composite with the highest contents of HA was still adoptable (~85%). In addition, the PCL/HA composite scaffolds were evaluated for their ability of osteogenic differentiation with human bone marrow stromal cell (hBMSC) in vitro. Alkaline phosphatase (ALP) activity, markers for osteoblastic differentiation, and total protein contents were evaluated in hBMSCs following 14 days of cultivation. The addition of HA particles enhanced proliferation of hBMSC during the test. Also, the differentiation ability of the cells was increased as HA particles were added. In this study, we concluded that PCL/HA composite scaffolds has great potential as a scaffold for bone tissue engineering.


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