Excessive Weight Loss in a Neonate - Novel Mutation Causing Primary Hypoaldosteronism

2021 ◽  
Vol 58 (12) ◽  
pp. 1186-1187
Author(s):  
Altaf Hussain ◽  
Rajendra Prasad Anne ◽  
Rahul Reddy Chintala ◽  
Sai Kiran Deshabhotla
Keyword(s):  
Weight Loss ◽  
Novel Mutation ◽  
Excessive Weight Loss ◽  
Excessive Weight

scholarly journals 39 Early Higher Parenteral Lipid Intake Decreases Extra-Uterine Growth Restriction in Very Low Birth weight Infants: A Randomized Controlled Trial

2020 ◽  
Vol 25 (Supplement_2) ◽  
pp. e15-e16
Author(s):  
Wissam Alburaki ◽  
Belal Alshaikh ◽  
Kamran Yusuf
Keyword(s):  
Weight Loss ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Very Low Birth Weight ◽  
Intervention Group ◽  
Excessive Weight Loss ◽  
Vlbw Infants ◽  
Excessive Weight ◽  
Uterine Growth

Abstract Background Approximately 43-65% of very low birth weight (VLBW) infants develop extra-uterine growth restriction (EUGR). EUGR is associated with a significant increase in the risk of neurodevelopmental impairment. Inadequate early postnatal nutrition results in excessive weight loss that cannot be explained by the physiologic contraction of body water alone. EUGR and postnatal growth failure are usually associated with negative early energy and nitrogen balance in the first week of life. Growth trajectories after initial weight loss have similar slopes regardless of gestational age, which indicates that the early excessive weight loss is a lead cause for EUGR. Objectives To study whether an early and higher parenteral lipid intake in the first week after birth would decrease the percentage of weight loss and subsequently the incidence of EUGR. Design/Methods This was a randomized, open-label, control trial of appropriate-for-gestational age VLBW infants admitted to our level III NICU. Lipid intake in the control group started at 0.5-1 g/kg/day and was increased daily by 0.5-1 g/kg/day until 3 g/kg/day was reached. The intervention group was started on 2 g/kg/day then increased to 3 g/kg/day the following day. Triglyceride levels were measured the day after the start and after each increase in lipid intake. Results Among the 176 infants assessed for eligibility, eighty-three were included in the trial. There were no significant differences between the control and the intervention group in mean gestational age (27.3 ± 2.4 vs. 27.1 ± 2.3 weeks respectively) or birth weight (1011 ± 250 vs. 1019 ± 271 g respectively). Infants in the intervention group were started on lipid earlier (13.8±7.8 vs. 17.5±7.8 h; p=0.03) and had higher cumulative lipid intake in the first 7 days of age (13.5±4.2 vs. 10.9±3.5 g/kg; p=0.004) that led to a protein to energy ratio; closer to the recommended values. Total fluid intake was similar between the two groups. Infants in the intervention group had a lower percentage of weight loss (10.4±3.6 vs. 12.7±4.6; p=0.02). The mean triglyceride level was higher in the intervention group (1.91± 0.79 vs. 1.49±0.54 mmol/L; p= 0.01), however, hypertriglyceridemia was similar between the two groups at 2 and 3 g/kg/day of lipid intake. Enteral energy and protein intake calculated weekly between the time of parenteral nutrition discontinuation and 36 weeks corrected gestational age (CGA) were similar between the 2 groups. EUGR at 36 weeks CGA was significantly lower in the intervention group (38.6% vs. 67.6%; p=0.01). Conclusion In VLBW infants, the provision of an early and higher dose of parenteral lipid in the first week of life results in less weight loss and lower incidence of EUGR.

PP042-SUN EXCESSIVE WEIGHT LOSS/WEIGHT GAIN BEFORE AND AFTER LIVER TRANSPLANTATION

2011 ◽  
Vol 6 (1) ◽  
pp. 39
Author(s):  
L.R. Anastâcio ◽  
E.G. Vilela ◽  
L.G. Ferreira ◽  
H.S. Ribeiro ◽  
A.S. Lima ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Weight Loss ◽  
Weight Gain ◽  
Excessive Weight Loss ◽  
Excessive Weight ◽  
Before And After

Excessive Weight Loss and Food Aversion in Athletes Simulating Anorexia Nervosa

PEDIATRICS ◽  
1980 ◽  
Vol 66 (1) ◽  
pp. 139-142
Author(s):  
Nathan J. Smith
Keyword(s):  
Weight Loss ◽  
Anorexia Nervosa ◽  
Dominant Role ◽  
Sports Participation ◽  
Optimum Level ◽  
Food Aversion ◽  
Excessive Weight Loss ◽  
Excessive Weight ◽  
Large Numbers ◽  
Definition Of

The dominant role of athletic activities in our society and the extent and intensity of sports participation by large numbers of young people create stresses causing a whole new constellation of health problems, both emotional and physical. One such problem is excessive weight loss and food aversion in athletes. The condition is in many ways similar to primary anorexia nervosa as commonly encountered in young women. The athlete avoiding food and experiencing extreme weight loss is most often a male, however, and does not suffer from severe, deep-seated emotional problems. He is typically a serious and outstanding student athlete fearing failure in meeting expectations of admiring coaches, teammates, and parents. The prognosis is excellent under the treatment by an informed, reassuring physician. The athlete's physician should provide a precise definition of optimum level of fatness for given sports participation. Guidance should be given in such a way that the desired level of fatness can be safely achieved, without threatening health and fitness.

Understanding cachexia and excessive weight loss in cancer

2005 ◽  
Vol 10 (11) ◽  
pp. 492-495 ◽  
Author(s):  
Laureen Hemming ◽  
David Maher
Keyword(s):  
Weight Loss ◽  
Excessive Weight Loss ◽  
Excessive Weight
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