Abundance and Associated Variations of Cytochrome P450 Drug-Metabolizing Enzymes in the Liver of East Asian Adults: A Meta-Analysis

2020 ◽  
Author(s):  
Xiao-Xiao An ◽  
Yichao Yu ◽  
Guo-Fu Li ◽  
Guo Yu
Keyword(s):  
Cytochrome P450 ◽  
Meta Analysis ◽  
East Asian ◽  
Drug Metabolizing Enzymes ◽  
Metabolizing Enzymes

Meta-analysis of contribution of genetic polymorphisms in drug-metabolizing enzymes or transporters to axitinib pharmacokinetics

2011 ◽  
Vol 68 (5) ◽  
pp. 645-655 ◽  
Author(s):  
Meghan Brennan ◽  
J. Andrew Williams ◽  
Ying Chen ◽  
Michael Tortorici ◽  
Yazdi Pithavala ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Meta Analysis ◽  
Drug Metabolizing Enzymes ◽  
Metabolizing Enzymes

Induction of cytochrome P450 and other drug metabolizing enzymes in rat liver following dietary exposure to Aroclor 1254

1991 ◽  
Vol 108 (2) ◽  
pp. 355-365 ◽  
Author(s):  
Ronald A. Lubet ◽  
Collins R. Jones ◽  
Diana L. Stockus ◽  
Stephen D. Fox ◽  
Raymond W. Nims
Keyword(s):  
Cytochrome P450 ◽  
Rat Liver ◽  
Dietary Exposure ◽  
Drug Metabolizing Enzymes ◽  
Aroclor 1254 ◽  
Metabolizing Enzymes

Interactions of omeprazole-based analogues with cytochrome P450 2C19: a computational study

2016 ◽  
Vol 12 (6) ◽  
pp. 1913-1921 ◽  
Author(s):  
Junhao Li ◽  
Hanwen Du ◽  
Zengrui Wu ◽  
Haixia Su ◽  
Guixia Liu ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Computational Study ◽  
Drug Metabolizing Enzymes ◽  
Clinical Use ◽  
Metabolizing Enzymes ◽  
Cytochrome P450 2C19

Cytochrome P450 2C19 (CYP2C19) is one of 57 drug metabolizing enzymes in humans and is responsible for the metabolism of ∼7–10% of drugs in clinical use.

Cytochrome P450, drug metabolizing enzymes and arachidonic acid metabolism in bovine ocular tissues

1987 ◽  
Vol 6 (4) ◽  
pp. 623-630 ◽  
Author(s):  
Michal L. Schwartzman ◽  
Jaime Masferrer ◽  
Michael W. Dunn ◽  
John C. McGiff ◽  
Nader G. Abraham
Keyword(s):  
Arachidonic Acid ◽  
Cytochrome P450 ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism ◽  
Drug Metabolizing Enzymes ◽  
Ocular Tissues ◽  
Metabolizing Enzymes ◽  
Bovine Ocular Tissues
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