Core-shell nanoparticulate formulation of gemcitabine: lyophilization, stability studies, and in vivo evaluation

2014 ◽  
Vol 4 (5-6) ◽  
pp. 439-451 ◽  
Author(s):  
Deepak Chitkara ◽  
Anupama Mittal ◽  
Ram I. Mahato ◽  
Neeraj Kumar
Keyword(s):  
Core Shell ◽  
Stability Studies ◽  
In Vivo Evaluation

Nanodesign of new self-assembling core-shell gellan-transfersomes loading baicalin and in vivo evaluation of repair response in skin

2018 ◽  
Vol 14 (2) ◽  
pp. 569-579 ◽  
Author(s):  
Maria Manconi ◽  
Maria Letizia Manca ◽  
Carla Caddeo ◽  
Donatella Valenti ◽  
Claudia Cencetti ◽  
...  
Keyword(s):  
Core Shell ◽  
In Vivo Evaluation ◽  
Self Assembling

Nevirapine Loaded Core Shell Gold Nanoparticles by Double Emulsion Solvent Evaporation: In vitro and In vivo Evaluation

2016 ◽  
Vol 13 (7) ◽  
pp. 1071-1083 ◽  
Author(s):  
Bhagyashree R. Dalvi ◽  
Ejaz A. Siddiqui ◽  
Asad S. Syed ◽  
Shilpa M. Velhal ◽  
Absar Ahmad ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Double Emulsion ◽  
Solvent Evaporation ◽  
Core Shell ◽  
In Vivo Evaluation

scholarly journals Preparation of Fluconazole -Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Hindustan Abdul Ahad ◽  
J. Sreeramulu ◽  
B. Suma Padmaja ◽  
M. Narasimha Reddy ◽  
P. Guru Prakash
Keyword(s):  
Moisture Absorption ◽  
Spectroscopic Studies ◽  
Stability Studies ◽  
Cyclodextrin Complex ◽  
In Vivo Evaluation ◽  
Folding Endurance ◽  
Site Of Action ◽  
Permeability Enhancer

The main purpose of the present study was to develop ocuserts of Fluconazole -CD (beta-cyclodextrin) complex and to evaluate both in vitro and in vivo. Fluconazole was made complex with -CD, and the release rate was controlled by HPMC K4M and ethyl cellulose polymers using dibutyl Phthalate as permeability enhancer. Drug-polymer interactions were studied by Fourier transform infrared spectroscopic studies. The formulated ocuserts were tested for physicochemical parameters of in vitro release and in vivo permeation in rabbits. The optimized formulations (F-5 and F-8) were subjected to stability studies. The formulated ocuserts were found to have good physical characters, thickness, diameter, uniformity in weight, folding endurance, less moisture absorption, and controlled release of drug both in vitro and in vivo. The optimized formulations retained their characteristics even after stability studies. The study clearly showed that this technique was an effective way of formulating ocuserts for retaining the drug concentration at the intended site of action for a sufficient period of time and to elicit the desired pharmacological response.

Core–shell hybrid nanocapsules for oral delivery of camptothecin: formulation development, in vitro and in vivo evaluation

2015 ◽  
Vol 17 (1) ◽  
Author(s):  
Hale Ünal ◽  
Ivana d’Angelo ◽  
Ester Pagano ◽  
Francesca Borrelli ◽  
Angelo Izzo ◽  
...  
Keyword(s):  
Oral Delivery ◽  
Core Shell ◽  
Formulation Development ◽  
In Vivo Evaluation ◽  
Development In Vitro

Preparation, characterization and in vivo evaluation of pH sensitive, safe quercetin-succinylated chitosan-alginate core-shell-corona nanoparticle for diabetes treatment

2018 ◽  
Vol 182 ◽  
pp. 42-51 ◽  
Author(s):  
Piyasi Mukhopadhyay ◽  
Subhajit Maity ◽  
Sudipto Mandal ◽  
Abhay Sankar Chakraborti ◽  
A.K. Prajapati ◽  
...  
Keyword(s):  
Ph Sensitive ◽  
Core Shell ◽  
Diabetes Treatment ◽  
In Vivo Evaluation
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