pH-responsive calcium alginate hydrogel laden with protamine nanoparticles and hyaluronan oligosaccharide promotes diabetic wound healing by enhancing angiogenesis and antibacterial activity

2018 ◽  
Vol 9 (1) ◽  
pp. 227-239 ◽  
Author(s):  
Tao Wang ◽  
Yan Zheng ◽  
Yijie Shi ◽  
Liang Zhao
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Calcium Alginate ◽  
Diabetic Wound ◽  
Ph Responsive ◽  
Alginate Hydrogel ◽  
Diabetic Wound Healing ◽  
Calcium Alginate Hydrogel ◽  
Hyaluronan Oligosaccharide

Rubidium-Containing Calcium Alginate Hydrogel for Antibacterial and Diabetic Skin Wound Healing Applications

2019 ◽  
Vol 5 (9) ◽  
pp. 4726-4738 ◽  
Author(s):  
Xiang He ◽  
Yufang Ding ◽  
Weijia Xie ◽  
RuoYu Sun ◽  
Nicola Claire Hunt ◽  
...  
Keyword(s):  
Wound Healing ◽  
Calcium Alginate ◽  
Skin Wound ◽  
Alginate Hydrogel ◽  
Skin Wound Healing ◽  
Calcium Alginate Hydrogel

Plasma Exosomes Loaded pH-Responsive Carboxymethylcellulose Hydrogel Promotes Wound Repair by Activating the Vascular Endothelial Growth Factor Signaling Pathway in Type 1 Diabetic Mice

2021 ◽  
Vol 17 (10) ◽  
pp. 2021-2033
Author(s):  
Lijuan Huang ◽  
Yijie Shi ◽  
Mengdie Li ◽  
Tao Wang ◽  
Liang Zhao
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Wound Healing ◽  
Growth Factor ◽  
Wound Repair ◽  
Vascular Endothelial ◽  
Diabetic Wound ◽  
Ph Responsive ◽  
Diabetic Wound Healing ◽  
Endothelial Growth Factor

Chronic wound healing plagues thousands of diabetic patients and brings social and economic burdens. Plasma exosomes (P-Exos), regarded as nanosized therapeutic agents, have shown therapeutic efficacy in promoting diabetic wound healing. The present work prepared the P-Exos-loaded pH-responsive carboxymethylcellulose (P-Exos-loaded CMC) hydrogel to investigate its ability to accelerate diabetic wound healing and to explore its underlying mechanisms. The results showed that the P-Exos-loaded CMC hydrogel was an effective therapeutic agent for accelerating diabetic wound repair. It promoted the local wound healing process in diabetic type 1 mice and enhanced angiogenesis and re-epithelialization via activating angiogenesis-related pathways mediated by vascular endothelial growth factor (VEGF).

Carbon quantum dot tailored calcium alginate hydrogel for pH responsive controlled delivery of vancomycin

2017 ◽  
Vol 109 ◽  
pp. 359-371 ◽  
Author(s):  
Niladri Sarkar ◽  
Gyanaranjan Sahoo ◽  
Rashmita Das ◽  
Gyanaranjan Prusty ◽  
Sarat K. Swain
Keyword(s):  
Quantum Dot ◽  
Calcium Alginate ◽  
Controlled Delivery ◽  
Ph Responsive ◽  
Alginate Hydrogel ◽  
Carbon Quantum Dot ◽  
Calcium Alginate Hydrogel

scholarly journals pH-responsive hydrogel loaded with insulin as a bioactive dressing for enhancing diabetic wound healing

2021 ◽  
Vol 210 ◽  
pp. 110104
Author(s):  
Zuhao Li ◽  
Yue Zhao ◽  
He Liu ◽  
Ming Ren ◽  
Zhonghan Wang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Diabetic Wound ◽  
Ph Responsive ◽  
Diabetic Wound Healing

The diabetic wound healing effect of a two-herb formula and its mechanisms of action

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
CBS Lau ◽  
VKM Lau ◽  
CL Liu ◽  
PKK Lai ◽  
JCW Tam ◽  
...  
Keyword(s):  
Wound Healing ◽  
Mechanisms Of Action ◽  
Diabetic Wound ◽  
Healing Effect ◽  
Diabetic Wound Healing ◽  
Wound Healing Effect

Critical Regulation of Angiogenesis by Nrf2 Signaling Is Absent in Diabetic Wound Healing

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 634-P
Author(s):  
PIUL S. RABBANI ◽  
JOSHUA A. DAVID ◽  
DARREN L. SULTAN ◽  
ALVARO P. VILLARREAL-PONCE ◽  
JENNIFER KWONG ◽  
...  
Keyword(s):  
Wound Healing ◽  
Diabetic Wound ◽  
Diabetic Wound Healing
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