Conversion rates of an interferon-γ release assay and the tuberculin skin test in the serial monitoring of healthcare workers

Infection ◽  
2012 ◽  
Vol 41 (2) ◽  
pp. 511-516 ◽  
Author(s):  
S. Y. Kim ◽  
M. S. Park ◽  
Y. S. Kim ◽  
S. K. Kim ◽  
J. Chang ◽  
...  
Keyword(s):  
Tuberculin Skin Test ◽  
Skin Test ◽  
Healthcare Workers ◽  
Interferon Γ ◽  
Conversion Rates ◽  
Release Assay

scholarly journals Evaluation of the tuberculin skin test and the interferon-γ release assay for TB screening in French healthcare workers

2009 ◽  
Vol 4 (1) ◽  
pp. 30 ◽  
Author(s):  
Dominique Tripodi ◽  
Benedicte Brunet-Courtois ◽  
Virginie Nael ◽  
Marie Audrain ◽  
Edmond Chailleux ◽  
...  
Keyword(s):  
Tuberculin Skin Test ◽  
Skin Test ◽  
Healthcare Workers ◽  
Interferon Γ ◽  
Release Assay

Negative Tuberculin Skin Test and Prediction of Reversion of QuantiFERON Interferon Gamma Release Assay in US Healthcare Workers

2016 ◽  
Vol 37 (4) ◽  
pp. 478-482 ◽  
Author(s):  
Wendy Thanassi ◽  
Art Noda ◽  
Beatriz Hernandez ◽  
Leah Friedman ◽  
Susan Dorman ◽  
...  
Keyword(s):  
Tuberculin Skin Test ◽  
Skin Test ◽  
Interferon Gamma ◽  
Healthcare Workers ◽  
Low Risk ◽  
Infect Control Hosp ◽  
Skin Tests ◽  
Interferon Gamma Release Assay ◽  
Negative Tuberculin Skin Test ◽  
Release Assay

QuantiFERON tuberculosis tests (QFT) reverted in (612) 77% of 1,094 low-risk healthcare workers (HCW) testing less than 1.16 IU/mL. Of HCW testing greater than 1.1 IU/mL, 33 (59%) of 56 with negative tuberculin skin tests (TST) reverted vs 8 (6%) of 125 with positive TSTs. Retesting low-risk QFT-positive and TST-negative HCW is prudent.Infect. Control Hosp. Epidemiol. 2016;37(4):478–482

Utility of an Interferon-γ Release Assay for Latent Tuberculosis Diagnosis in a Case of Bullous Pemphigoid

2009 ◽  
Vol 13 (5) ◽  
pp. 280-282 ◽  
Author(s):  
Alfred Goodfellow ◽  
Douglas N. Keeling ◽  
Robert C. Hayes ◽  
Duncan Webster
Keyword(s):  
Tuberculin Skin Test ◽  
Bullous Pemphigoid ◽  
Skin Test ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Interferon Γ ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Cutaneous Disease ◽  
Release Assay

Background: With increasing use of immunosuppressive therapy, including tumor necrosis factor a inhibitors, there is concern about infectious complications, including reactivation of latent Mycobacterium tuberculosis infection. Routine testing prior to administration of systemic immunosuppression includes the tuberculin skin test, which lacks sensitivity and specificity and may be difficult to interpret in the presence of extensive cutaneous disease. Treatment of individuals with latent tuberculosis infection is recommended when immunosuppressive medications are to be employed. Observations: We report a case in which a diagnosis of latent tuberculosis infection in a patient with extensive bullous pemphigoid was clarified by the use of an interferon-γ release assay after equivocal tuberculin skin test results. Conclusion: Interferon-γ release assays are useful adjuncts to the tuberculin skin test in the diagnosis of latent tuberculosis infection in the setting of extensive cutaneous disease.

scholarly journals Discordance Between Tuberculin Skin Test and Interferon-γ Release Assay in Children Younger Than 5 Years Who Have Been Vaccinated With Bacillus Calmette-Guérin

2015 ◽  
Vol 46 (3) ◽  
pp. 200-206 ◽  
Author(s):  
Ivan Pavić ◽  
Vera Katalinić-Janković ◽  
Jasna Čepin-Bogović ◽  
Arnes Rešić ◽  
Slavica Dodig
Keyword(s):  
Tuberculin Skin Test ◽  
Skin Test ◽  
Interferon Γ ◽  
Bacillus Calmette Guerin ◽  
Release Assay

scholarly journals Monocyte metabolic transcriptional programs associate with resistance to tuberculin skin test/interferon-γ release assay conversion

2021 ◽  
Author(s):  
Jason D. Simmons ◽  
Phu T. Van ◽  
Catherine M. Stein ◽  
Violet Chihota ◽  
Thobani Ntshiqa ◽  
...  
Keyword(s):  
Tuberculin Skin Test ◽  
Skin Test ◽  
Interferon Γ ◽  
Release Assay

scholarly journals IFN-γ release assay versus tuberculin skin test for monitoring TB infection in healthcare workers

2013 ◽  
Vol 11 (1) ◽  
pp. 37-48 ◽  
Author(s):  
Albert Nienhaus ◽  
Felix C Ringshausen ◽  
José Torres Costa ◽  
Anja Schablon ◽  
Dominique Tripodi
Keyword(s):  
Tuberculin Skin Test ◽  
Skin Test ◽  
Healthcare Workers ◽  
Release Assay ◽  
Ifn Γ
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