scholarly journals Intraoperative Photoactivated Chromophore for Infectious Keratitis–Corneal Cross-Linking (PACK-CXL) During Penetrating Keratoplasty for the Management of Fungal Keratitis in an Immunocompromised Patient

2019 ◽  
Vol 8 (3) ◽  
pp. 491-495
Author(s):  
Dimitrios G. Mikropoulos ◽  
George D. Kymionis ◽  
Nafsika Voulgari ◽  
Eirini Kaisari ◽  
Konstantinos A. Nikolakopoulos ◽  
...  
Keyword(s):  
Penetrating Keratoplasty ◽  
Immunocompromised Patient ◽  
Fungal Keratitis ◽  
Cross Linking ◽  
Infectious Keratitis

scholarly journals Fungal keratitis after small incision lenticule extraction (SMILE): a case report and review of the literature

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mohammad Soleimani ◽  
Ali A. Haydar
Keyword(s):  
Case Report ◽  
Penetrating Keratoplasty ◽  
Fungal Keratitis ◽  
Infectious Keratitis ◽  
Review Of The Literature ◽  
Small Incision Lenticule Extraction ◽  
Hand Motion ◽  
Small Incision ◽  
Aggressive Management ◽  
Lenticule Extraction

Abstract Purpose To report a case of perforated fungal keratitis after small incision lenticule extraction (SMILE) treated with penetrating keratoplasty (PKP). Methods Case report and literature review. Results A 41-year-old woman presented with culture-proven unilateral fungal keratitis 4 days after uneventful SMILE. Her visual acuity was hand motion. The patient was treated with voriconazole irrigation (50 μm/0.1 ml) of the pocket and intrastromal voriconazole injection, in addition to systemic and topical antifungals. Despite aggressive management and decreased infiltration, the cornea was perforated and subsequently treated with PKP. Conclusions Infectious keratitis after SMILE is unusual. To our knowledge, this is the first report of perforated fungal keratitis post-SMILE. PKP eradicated the infection.

scholarly journals Comparison of corneal collagen cross-linking (PACK-CXL) and voriconazole treatments in experimental fungal keratitis

2018 ◽  
Vol 97 (1) ◽  
pp. e91-e96 ◽  
Author(s):  
Hüseyin Baran Özdemir ◽  
Ayşe Kalkancı ◽  
Kamil Bilgihan ◽  
Pınar Uyar Göçün ◽  
Betül Öğüt ◽  
...  
Keyword(s):  
Fungal Keratitis ◽  
Cross Linking ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Infectious Keratitis in Western Nepal: An Experience from a Tertiary Care Hospital

2018 ◽  
Author(s):  
Rajani Shrestha ◽  
Niranjan Nayak ◽  
Babita Gurung ◽  
Shishir Gokhale
Keyword(s):  
Antibiotic Susceptibility ◽  
Fungal Growth ◽  
Severe Form ◽  
Fungal Keratitis ◽  
Clinical Severity ◽  
Diffusion Method ◽  
Eye Drops ◽  
Infectious Keratitis ◽  
History Of ◽  
Predisposing Conditions

Abstract Background: Corneal blindness is a major public health problem worldwide and infectious keratitis is one of its leading causes. The aim was is to analyze the microbial etiology of corneal ulcers and to determine the antibiotic susceptibility pattern of bacterial isolates in order to find out the existing drug resistance pattern. Methods: Corneal scrapings were collected as per the standard procedure. All the isolates were identifies by conventional microbiological techniques. Antibiotic susceptibility testing was performed using disc diffusion method. Clinical grading of the ulcerative lesion was carried out by the recommended protocol. Results: Among the 84 cases of clinically diagnosed infectious keratitis investigated, 33 (39.3%) were farmers by occupation. All cases were reviewed for predisposing conditions and clinical severity. Ulcers were categorized as mild in 49 cases moderate in 12 and severe in 23 cases. Predisposing conditions were found in 55(65.5%) of the 84 cases. Forty-two cases showed culture positivity. Among these 42; 25 (29.7%) yielded fungal growth, 13(30.1%) yielded bacteria and the rest 4 (4.7%) showed mixed growth. Aspergillus spp. (10/29; 34.5%) were the commonest fungi isolated followed by Fusarium spp. (6/29; 20%). Similarly, Staphylococcus aureus, (8/17; 47%) was the most common among bacteria. Majority i.e 66.7% (26 of 39) of those having trauma, as the predisposing factor developed moderate to severe degree of corneal ulceration as compared to only 20% (9 of 45) of those without any history of trauma. (p<0.001). Interestingly, 20(68.9%) of the 29 cases that had yielded fungal growth on culture had had previous history of ocular trauma in contrast to only 19 (34.5%) of the 55 who had non-fungal origin of keratitis. (p=0.003). Fungal keratitis cases presented with more severe form of ulcerative lesions exhibiting more often with infiltrates and hypopion as compared to bacterial keratitis. Topical administration of fourth generation fluoroquinolone eye drops remained the most effective drug of choice with clinical improvement in all cases without any complications. Conclusions: Trauma with vegetative matter predisposed to most cases of fungal keratitis. Severe form of ulceration was noticed in patients with fungal infection. Surveillance of the antibiotic sensitivity is needed for quality patient management.

scholarly journals Microcyclosporella mali: a novel fungal keratitis in a post-penetrating keratoplasty patient

2015 ◽  
Vol 2015 (feb27 1) ◽  
pp. bcr2014207416-bcr2014207416 ◽  
Author(s):  
N. Vyas ◽  
S. Al-Hashimi ◽  
W. Munir
Keyword(s):  
Penetrating Keratoplasty ◽  
Fungal Keratitis
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