Surgical Considerations in Advance Basal Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, and Cutaneous Melanoma: a Head and Neck Perspective

2018 ◽  
Vol 6 (2) ◽  
pp. 140-150
Author(s):  
Tom C. Zhou ◽  
Antoine E. Eskander ◽  
Matthew O. Old ◽  
Stephen Y. Kang ◽  
Theodoros N. Teknos
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Basal Cell ◽  
Cutaneous Melanoma ◽  
Cutaneous Squamous Cell Carcinoma

scholarly journals Methyltransferases in the Pathogenesis of Keratinocyte Cancers

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3402
Author(s):  
Eun Kyung Ko ◽  
Brian C. Capell
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Histone Methylation ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Therapeutic Approaches ◽  
Novel Therapeutic

Recent evidence suggests that the disruption of gene expression by alterations in DNA, RNA, and histone methylation may be critical contributors to the pathogenesis of keratinocyte cancers (KCs), made up of basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), which collectively outnumber all other human cancers combined. While it is clear that methylation modifiers are frequently dysregulated in KCs, the underlying molecular and mechanistic changes are only beginning to be understood. Intriguingly, it has recently emerged that there is extensive cross-talk amongst these distinct methylation processes. Here, we summarize and synthesize the latest findings in this space and highlight how these discoveries may uncover novel therapeutic approaches for these ubiquitous cancers.

Risk of cutaneous squamous cell carcinoma after treatment of basal cell carcinoma with vismodegib

2017 ◽  
Vol 77 (4) ◽  
pp. 713-718 ◽  
Author(s):  
Tina Bhutani ◽  
Michael Abrouk ◽  
Camelia S. Sima ◽  
Natalia Sadetsky ◽  
Jeannie Hou ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Cutaneous Squamous Cell Carcinoma

Geographic Pathology of Skin Cancer

1999 ◽  
Vol 3 (3) ◽  
pp. 120-122
Author(s):  
Robert Jackson
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Basal Cell ◽  
Sun Exposure

Background: The development of knowledge concerning the role of sun exposure in causing skin cancer has been a gradual one. Objective: This article reviews the article by Urbach who used manikin coated with an ultraviolet dosimeter to see exactly where on the head and neck the exposure was greatest. Conclusion: Urbach showed that the areas of greatest sun exposure on his manikins corresponded with the location of 95% of squamous cell carcinoma and 66% of basal cell carcinoma. He also clearly showed the importance of scattered sky and reflected radiation.

Perineural Invasion of Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma

2008 ◽  
Vol 34 (12) ◽  
pp. 1642-1651
Author(s):  
DAVID E. GEIST ◽  
MARIA GARCIA-MOLINER ◽  
MARKUS M. FITZEK ◽  
HANNAH CHO ◽  
GARY S. ROGERS
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Perineural Invasion ◽  
Cutaneous Squamous Cell Carcinoma

scholarly journals Increased Risk of Cutaneous Squamous Cell Carcinoma After Vismodegib Therapy for Basal Cell Carcinoma

2016 ◽  
Vol 152 (5) ◽  
pp. 527 ◽  
Author(s):  
Shalini V. Mohan ◽  
Julia Chang ◽  
Shufeng Li ◽  
A. Solomon Henry ◽  
Douglas J. Wood ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Increased Risk
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