scholarly journals Risks of Cardiac Valve Regurgitation and Heart Failure Associated with Ergot- and Non-Ergot-Derived Dopamine Agonist Use in Patients with Parkinson’s Disease: A Systematic Review of Observational Studies

CNS Drugs ◽  
2015 ◽  
Vol 29 (12) ◽  
pp. 985-998 ◽  
Author(s):  
Tanja Tran ◽  
James M. Brophy ◽  
Samy Suissa ◽  
Christel Renoux
2007 ◽  
Vol 13 ◽  
pp. S120
Author(s):  
K. Kimura ◽  
T. Sekiguchi ◽  
Y. Higashiyama ◽  
C. Kugimoto ◽  
Y. Baba ◽  
...  

2019 ◽  
Vol 22 (5-6) ◽  
pp. 172-202 ◽  
Author(s):  
Carolina Vaccari ◽  
Regina El Dib ◽  
Huda Gomaa ◽  
Luciane C Lopes ◽  
João Lauro de Camargo

Author(s):  
Charmaine Pearl Da Cunha ◽  
Pratiksha Tilak Rao ◽  
Suruliraj Karthikbabu

Abstract Introduction The aim of this systematic review is to present the existing literature on the clinical motor, and non-motor factors contributing to sit-to-stand transfer in individuals with Parkinson's disease. Data synthesis Five databases (PubMed, PEDro, Cochrane, SCOPUS, and Ovid) were searched for literature on the contributing factors to sit-to-stand performance in Parkinson's disease. A quality check of these observational studies was done using the 'strengthening the reporting of observational studies in epidemiology' (STROBE) statement and the tool of the 'National Heart, Lung, and Blood Institute' (NHLBI). Descriptive and quantitative data were extracted and compiled, and a meta-analysis was performed to compute the standardised mean difference. Results Thirteen studies were selected; a majority of them provided a high-to-moderate level of evidence. Ten were cross-sectional, while the other three were case–control studies. Collectively, individuals with Parkinson's disease had a prolonged transfer time than those of age-matched healthy peers, particularly from peak horizontal velocity phase to seat-off phase, implying bradykinesia. A reduction in peak and rate to peak joint torques was also related to the decreased pace and stability of the sit-to-stand movement in individuals with Parkinson's disease. Additionally, they demonstrated exaggerated trunk flexion as a postural stabilisation strategy, allowing them to maintain and manoeuvre the relative positions of their centre of mass through the transitional phase of the transfer. Conclusion As per the existing literature, an alteration in strength, overall body bradykinesia, balance, posture, as well as cognition may result in an impaired sit-to-stand transfer in individuals with Parkinson's disease.


2018 ◽  
Vol 43 ◽  
pp. 40-46 ◽  
Author(s):  
Xinglong Yang ◽  
Bin Liu ◽  
Hao Shen ◽  
Shimei Li ◽  
Quanzhen Zhao ◽  
...  

2012 ◽  
Vol 65 (3) ◽  
pp. 358-364 ◽  
Author(s):  
M. Mostafa Mokhles ◽  
Gianluca Trifirò ◽  
Jeanne P. Dieleman ◽  
Mendel D. Haag ◽  
Eva M. van Soest ◽  
...  

Sensors ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 880 ◽  
Author(s):  
María del Rosario Ferreira-Sánchez ◽  
Marcos Moreno-Verdú ◽  
Roberto Cano-de-la-Cuerda

Rigidity is one of the cardinal symptoms of Parkinson’s disease (PD). Present in up 89% of cases, it is typically assessed with clinical scales. However, these instruments show limitations due to their subjectivity and poor intra- and inter-rater reliability. To compile all of the objective quantitative methods used to assess rigidity in PD and to study their validity and reliability, a systematic review was conducted using the Web of Science, PubMed, and Scopus databases. Studies from January 1975 to June 2019 were included, all of which were written in English. The Strengthening the Reporting of observational studies in Epidemiology Statement (STROBE) checklist for observational studies was used to assess the methodological rigor of the included studies. Thirty-six studies were included. Rigidity was quantitatively assessed in three ways, using servomotors, inertial sensors, and biomechanical and neurophysiological study of muscles. All methods showed good validity and reliability, good correlation with clinical scales, and were useful for detecting rigidity and studying its evolution. People with PD exhibit higher values in terms of objective muscle stiffness than healthy controls. Rigidity depends on the angular velocity and articular amplitude of the mobilization applied. There are objective, valid, and reliable methods that can be used to quantitatively assess rigidity in people with PD.


Drug Safety ◽  
2012 ◽  
Vol 35 (2) ◽  
pp. 159-171 ◽  
Author(s):  
Gianluca Trifirò ◽  
M. Mostafa Mokhles ◽  
Jeanne P. Dieleman ◽  
Eva M. van Soest ◽  
Katia Verhamme ◽  
...  

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