Cerebral oedema large burden in US patients with large hemispheric infarction

2021 ◽  
Vol 886 (1) ◽  
pp. 6-6
Keyword(s):  
Cerebral Oedema ◽  
Hemispheric Infarction

scholarly journals R1352Q CACNA1A Variant in a Patient with Sporadic Hemiplegic Migraine, Ataxia, Seizures and Cerebral Oedema: A Case Report

2021 ◽  
pp. 123-130
Author(s):  
Anker Stubberud ◽  
Emer O’Connor ◽  
Erling Tronvik ◽  
Henry Houlden ◽  
Manjit Matharu
Keyword(s):  
Mental Retardation ◽  
Case Report ◽  
Genetic Testing ◽  
Head Trauma ◽  
Cerebral Oedema ◽  
De Novo ◽  
Minor Head Trauma ◽  
Hemiplegic Migraine ◽  
Wide Range ◽  
History Of

Mutations in the <i>CACNA1A</i> gene show a wide range of neurological phenotypes including hemiplegic migraine, ataxia, mental retardation and epilepsy. In some cases, hemiplegic migraine attacks can be triggered by minor head trauma and culminate in encephalopathy and cerebral oedema. A 37-year-old male without a family history of complex migraine experienced hemiplegic migraine attacks from childhood. The attacks were usually triggered by minor head trauma, and on several occasions complicated with encephalopathy and cerebral oedema. Genetic testing of the proband and unaffected parents revealed a de novo heterozygous nucleotide missense mutation in exon 25 of the <i>CACNA1A</i> gene (c.4055G&#x3e;A, p.R1352Q). The R1352Q <i>CACNA1A</i> variant shares the phenotype with other described <i>CACNA1A</i> mutations and highlights the interesting association of trauma as a precipitant for hemiplegic migraine. Subjects with early-onset sporadic hemiplegic migraine triggered by minor head injury or associated with seizures, ataxia or episodes of encephalopathy should be screened for mutations. These patients should also be advised to avoid activities that may result in head trauma, and anticonvulsants should be considered as prophylactic migraine therapy.

scholarly journals European Stroke Organisation (ESO) guidelines on the management of space-occupying brain infarction

2021 ◽  
pp. 239698732110141
Author(s):  
H Bart van der Worp ◽  
Jeannette Hofmeijer ◽  
Eric Jüttler ◽  
Avtar Lal ◽  
Patrik Michel ◽  
...  
Keyword(s):  
Brain Infarction ◽  
Treatment Strategies ◽  
Surgical Decompression ◽  
Cerebellar Infarction ◽  
High Quality ◽  
Risk Of Death ◽  
Grade Approach ◽  
Quality Evidence ◽  
Hemispheric Infarction

Space-occupying brain oedema is a potentially life-threatening complication in the first days after large hemispheric or cerebellar infarction. Several treatment strategies for this complication are available, but the size and quality of the scientific evidence on which these strategies are based vary considerably. The aim of this Guideline document is to assist physicians in their management decisions when treating patients with space-occupying hemispheric or cerebellar infarction. These Guidelines were developed based on the European Stroke Organisation (ESO) standard operating procedure and followed the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. A working group identified 13 relevant questions, performed systematic reviews and meta-analyses of the literature, assessed the quality of the available evidence, and wrote evidence-based recommendations. An expert consensus statement was provided if not enough evidence was available to provide recommendations based on the GRADE approach. We found high-quality evidence to recommend surgical decompression to reduce the risk of death and to increase the chance of a favourable outcome in adult patients aged up to and including 60 years with space-occupying hemispheric infarction who can be treated within 48 hours of stroke onset, and low-quality evidence to support this treatment in older patients. There is continued uncertainty about the benefit and risks of surgical decompression in patients with space-occupying hemispheric infarction if this is done after the first 48 hours. There is also continued uncertainty about the selection of patients with space-occupying cerebellar infarction for surgical decompression or drainage of cerebrospinal fluid. These Guidelines further provide details on the management of specific subgroups of patients with space-occupying hemispheric infarction, on the value of monitoring of intracranial pressure, and on the benefits and risks of medical treatment options. We encourage new high-quality studies assessing the risks and benefits of different treatment strategies for patients with space-occupying brain infarction.

Fatal Cerebral oedema associated with hyponatraemia

1999 ◽  
Vol 16 (1) ◽  
pp. 1-2 ◽  
Author(s):  
John Rattenbury ◽  
S T Jones ◽  
S W Hancock
Keyword(s):  
Cerebral Oedema

scholarly journals Sinking Skin Flap Syndrome and Paradoxical Herniation After Hemicraniectomy for Malignant Hemispheric Infarction

Stroke ◽  
2010 ◽  
Vol 41 (3) ◽  
pp. 560-562 ◽  
Author(s):  
Mariana Sarov ◽  
Jean-Pierre Guichard ◽  
Salvatore Chibarro ◽  
Emilie Guettard ◽  
Ophelia Godin ◽  
...  
Keyword(s):  
Skin Flap ◽  
Hemispheric Infarction

Cerebral oedema in lambs associated with hypocuprosis, and its relationship to swayback

1966 ◽  
Vol 76 (3) ◽  
pp. 285-IN16 ◽  
Author(s):  
H.E. Roberts ◽  
B.M. Williams ◽  
A. Harvard
Keyword(s):  
Cerebral Oedema

Measurement of canine cerebral oedema using vector impedance methods

1991 ◽  
Vol 13 (4) ◽  
pp. 233-236 ◽  
Author(s):  
H.P. Kao ◽  
E. Shwedyk ◽  
E.R. Cardoso
Keyword(s):  
Cerebral Oedema

scholarly journals Hypertension, cerebral oedema and fundoscopy

2003 ◽  
Vol 18 (11) ◽  
pp. 2424-2427 ◽  
Author(s):  
R. C. Bakker
Keyword(s):  
Cerebral Oedema

High altitude cerebral oedema

2016 ◽  
Vol 6 (3) ◽  
pp. 126-128 ◽  
Author(s):  
K.V.S. Hari Kumar ◽  
K.P. Shijith ◽  
Dalbara Singh
Keyword(s):  
High Altitude ◽  
Cerebral Oedema

Case report: Transient unilateral cerebral oedema in hemiplegic migraine: MR imaging and angiography

1996 ◽  
Vol 51 (1) ◽  
pp. 72-76 ◽  
Author(s):  
J.F.M. Meaney ◽  
C.E. Willaims ◽  
P.R.D. Humphrey
Keyword(s):  
Case Report ◽  
Mr Imaging ◽  
Cerebral Oedema ◽  
Hemiplegic Migraine
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