scholarly journals Coronavirus-vaccine-Wuhan-Institute-of-Biological-Products

2021 ◽  
Vol 1884 (1) ◽  
pp. 139-139
Author(s):  
ravinder kasturi

The global struggle against corona virus disease 2019(COVID19) is now in its 8th month since the pandemic virus SARS –COV2 has first emerged.The severe economic,personal and psychological adverse effects of shutdowns and social distancing make these effective preventive measures challenging to sustain long term.Safe and effective COVID-19 vaccine could lead to a level of global immunity that stops the pandemic.This is the anti COVID-19 intervention most public health leaders and many people long for the most. As of August 2020,there were 231 vaccine candidatesin development although no vaccine has completed clinical trials to prove its safety and efficacy.1 26 vaccine candidates are in clinical trials with 20 still in phase l-ll and 6 beginning phase lIl2 among which three are Chinese COVID-19 vaccines (inactivated virus based) from Sinovac/Institute Butantan, Wuhan institute of biological products/sinopharm and beijing institute of biological products/sinopharm,the other three leading candidates are developed by oxford/astrazeneca(modified adenovirus vector),moderna/NIAID(mRNA based) and Bio-N tech/Fosun pharma/Pfizer (mRNA based) WHO however warned “entering phase lll doesn’t mean nearly there” as there is no guarantee that any of these six will give us the answer. Sputnik 5 Russian based COVID-19 vaccine (adeno based) is a medical coup,a propaganda coup,a political and marketing coup.Phase l/ll trials are inadequate to prove it’s efficacy and safety because of three reasons 1) it was tested only on 76 people 2 it is a two dose vaccine but in phase l/ll only one dose was given 3 it’s phase l/ll results were not published therefore not peer reviewed.3 India based Bharath biotech(inactivated virus based)/ zydus cadila( DNA based) vaccine trials demonstrated an encouraging safety profile in phase l and moved to phase ll


2019 ◽  
Vol 6 (1) ◽  
pp. 40-46
Author(s):  
Tadjidin Uraimov Tadjidin Uraimov ◽  
◽  
Matluba Yakhyokulova

Author(s):  
O.I. Vlasova ◽  
◽  
E.A. Danilets ◽  
V.M. Perederieva ◽  
I.A. Volters

the article provides data on the effectiveness of the use of biological products in the fight against septoria infection of winter wheat, placed on various predecessors and the formation of yield.


Spring wheat is the main grain crop. Stable production of high-quality wheat grain is the key to the country's food independence. Therefore, the study of the elements of growing spring wheat technology, aimed at increasing the productivity of crops, is important. The study of the interaction of plants and microorganisms depending on the level of mineral nutrition in crop planning is currently ofparticular relevance. The use of biological products, growth regulators improves the mineral nutrition of plants, increases productivity and its quality, and also provides savings in mineral fertilizers. In the upper Volga region, the main spring crops are wheat, barley and oats. To further increase them in the region, it is necessary to study the characteristics of the formation of yields and determine the most productive crops depending on the level of nutrition, biological products and growth regulators. The scientific article presents the results of the study of these drugs on the productivity of spring wheat. In field experiments, it was planned to get 30, 40 and 50 tons of grain per hectare. Fertilizers for the planned harvest were made taking into account the agrochemical properties of the soil. From biological products used Flavobacterin, which has a protective effect against diseases and improves product quality, from growth regulators used agrochemicals HUMATE + 7 (10 % liquid concentrate), which is characterized by high biological activity. The yield level was determined taking into account the average long-term moisture supply and qualitative assessment of arable land. The indicators of photosynthetic activity of crops, crop and its structure, quality characteristics of grain and economic efficiency of growing spring wheat in the upper Volga region are presented. As a result of researches the optimum level of mineral nutrition for wheat, the efficacy of agrochemical diazotroph and programming yields of spring wheat, determined the photosynthetic activity of crops and grain yield, calculated economic efficiency of the studied techniques and established the qualitative characteristics of the crop. The program for obtaining the planned wheat yields in the years of the experiments was completed by 68-91 %. Close to the planned the program was implemented using a biological product and growth regulator-74-91 %.


2018 ◽  
Vol 62 (1) ◽  
pp. 31-37
Author(s):  
Noritaka Hashii ◽  
Akiko Ishii-Watabe

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 750
Author(s):  
Lu-Yan An ◽  
Zhen Dai ◽  
Bin Di ◽  
Li-Li Xu

It is counterintuitive that chemical reactions can be accelerated by freezing, but this amazing phenomenon was discovered as early as the 1960s. In frozen systems, the increase in reaction rate is caused by various mechanisms and the freeze concentration effect is the main reason for the observed acceleration. Some accelerated reactions have great application value in the chemistry synthesis and environmental fields; at the same time, certain reactions accelerated at low temperature during the storage of food, medicine, and biological products should cause concern. The study of reactions accelerated by freezing will overturn common sense and provide a new strategy for researchers in the chemistry field. In this review, we mainly introduce various mechanisms for accelerating reactions induced by freezing and summarize a variety of accelerated cryochemical reactions and their applications.


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