Proximal femur geometry assessed by hip structural analysis in hip fracture in women

2015 ◽  
Vol 27 (S1) ◽  
pp. 17-21 ◽  
Author(s):  
Giovanni Iolascon ◽  
Antimo Moretti ◽  
Giovanni Cannaviello ◽  
Giuseppina Resmini ◽  
Francesca Gimigliano
Keyword(s):  
Hip Fracture ◽  
Structural Analysis ◽  
Proximal Femur ◽  
Hip Structural Analysis ◽  
Femur Geometry

Osteoporotic Hip Fracture Prediction: Is T-Score-Based Criterion Enough? A Hip Structural Analysis-Based Model

2018 ◽  
Vol 140 (11) ◽  
Author(s):  
Alessandra Aldieri ◽  
Mara Terzini ◽  
Giangiacomo Osella ◽  
Adriano M. Priola ◽  
Alberto Angeli ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Structural Analysis ◽  
Fracture Risk ◽  
Proximal Femur ◽  
Patient Specific ◽  
Multivariate Linear Regression Analysis ◽  
Hip Structural Analysis ◽  
Mineral Density ◽  
Neck Shaft Angle ◽  
Adopted Model

At present, the current gold-standard for osteoporosis diagnosis is based on bone mineral density (BMD) measurement, which, however, has been demonstrated to poorly estimate fracture risk. Further parameters in the hands of the clinicians are represented by the hip structural analysis (HSA) variables, which include geometric information of the proximal femur cross section. The purpose of this study was to investigate the suitability of HSA parameters as additional hip fracture risk predictors. With this aim, twenty-eight three-dimensional patient-specific models of the proximal femur were built from computed tomography (CT) images and a sideways fall condition was reproduced by finite element (FE) analyses. A tensile or compressive predominance based on minimum and maximum principal strains was determined at each volume element and a risk factor (RF) was calculated. The power of HSA variables combinations to predict the maximum superficial RF values was assessed by multivariate linear regression analysis. The optimal regression model, identified through the Akaike information criterion (AIC), only comprises two variables: the buckling ratio (BR) and the neck-shaft angle (NSA). In order to validate the study, the model was tested on two additional patients who suffered a hip fracture after a fall. The results classified the patients in the high risk level, confirming the prediction power of the adopted model.

scholarly journals Prediction of Incident Hip Fracture Risk by Femur Geometry Variables Measured by Hip Structural Analysis in the Study of Osteoporotic Fractures

2008 ◽  
Vol 23 (12) ◽  
pp. 1892-1904 ◽  
Author(s):  
Stephen Kaptoge ◽  
Thomas J Beck ◽  
Jonathan Reeve ◽  
Katie L Stone ◽  
Teresa A Hillier ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Structural Analysis ◽  
Fracture Risk ◽  
Osteoporotic Fractures ◽  
Hip Structural Analysis ◽  
Hip Fracture Risk ◽  
Femur Geometry

scholarly journals Hip Structural Analysis Reveals Impaired Hip Geometry in Girls With Type 1 Diabetes

2020 ◽  
Vol 105 (12) ◽  
pp. e4848-e4856
Author(s):  
Taïsha V Joseph ◽  
Signe Caksa ◽  
Madhusmita Misra ◽  
Deborah M Mitchell
Keyword(s):  
Type 1 Diabetes ◽  
Hip Fracture ◽  
Structural Analysis ◽  
Bone Age ◽  
Sectional Area ◽  
Hip Structural Analysis ◽  
Hip Geometry ◽  
Cross Sectional ◽  
Skeletal Fragility

Abstract Context Among patients with type 1 diabetes (T1D), the risk of hip fracture is up to 6-fold greater than that of the general population. However, the cause of this skeletal fragility remains poorly understood. Objective To assess differences in hip geometry and imaging-based estimates of bone strength between youth with and without T1D using dual-energy x-ray absorptiometry (DXA)-based hip structural analysis. Design Cross-sectional comparison. Participants Girls ages 10 to 16 years, including n = 62 with T1D and n = 61 controls. Results The groups had similar age, bone age, pubertal stage, height, lean mass, and physical activity. Bone mineral density at the femoral neck and total hip did not differ in univariate comparisons but was lower at the femoral neck in T1D after adjusting for bone age, height, and lean mass. Subjects with T1D had significantly lower cross-sectional area, cross-sectional moment of inertia, section modulus, and cortical thickness at the narrow neck, with deficits of 5.7% to 10.3%. Cross-sectional area was also lower at the intertrochanteric region in girls with T1D. Among those T1D subjects with HbA1c greater than the cohort median of 8.5%, deficits in hip geometry and strength estimates were more pronounced. Conclusions DXA-based hip structural analysis revealed that girls with T1D have unfavorable geometry and lower estimates of bone strength at the hip, which may contribute to skeletal fragility and excess hip fracture risk in adulthood. Higher average glycemia may exacerbate effects of T1D on hip geometry.

A new value of proximal femur geometry to evaluate hip fracture risk: true moment arm

2008 ◽  
Vol 18 (2) ◽  
pp. 101-107 ◽  
Author(s):  
H. Ulusoy ◽  
A. Bilgici ◽  
O. Kuru ◽  
N. Sarica ◽  
S. Arslan ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Fracture Risk ◽  
Proximal Femur ◽  
Moment Arm ◽  
Hip Fracture Risk ◽  
Femur Geometry

The association of proximal femur geometry with hip fracture risk

2008 ◽  
Vol 21 (6) ◽  
pp. 575-580 ◽  
Author(s):  
V. Ercan Dinçel ◽  
Meltem Şengelen ◽  
Vesile Sepici ◽  
Turgay Çavuşoğlu ◽  
Behçet Sepici
Keyword(s):  
Hip Fracture ◽  
Fracture Risk ◽  
Proximal Femur ◽  
Hip Fracture Risk ◽  
Femur Geometry

Effects of denosumab on structural geometry of the proximal femur in postmenopausal women with low bone mass as determined by hip structural analysis

2007 ◽  
Vol 10 (2) ◽  
pp. S200
Author(s):  
Paul D. Miller ◽  
E. Michael Lewiecki ◽  
Dieter Felsenberg ◽  
Cesar Libanati ◽  
Yu Liu ◽  
...  
Keyword(s):  
Structural Analysis ◽  
Bone Mass ◽  
Postmenopausal Women ◽  
Proximal Femur ◽  
Low Bone Mass ◽  
Hip Structural Analysis ◽  
Structural Geometry

A new value of proximal femur geometry to evaluate hip fracture risk: True moment arm

2008 ◽  
Vol 18 (2) ◽  
pp. 101-107 ◽  
Author(s):  
H. Ulusoy ◽  
A. Bilgici ◽  
O. Kuru ◽  
N. Sarica ◽  
S. Arslan ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Fracture Risk ◽  
Proximal Femur ◽  
Moment Arm ◽  
Hip Fracture Risk ◽  
Femur Geometry

Hip Fracture Risk and Proximal Femur Geometry from DXA Scans

2002 ◽  
Vol 13 (7) ◽  
pp. 542-550 ◽  
Author(s):  
C. Bergot ◽  
V. Bousson ◽  
A. Meunier ◽  
M. Laval-Jeantet ◽  
J. D. Laredo
Keyword(s):  
Hip Fracture ◽  
Fracture Risk ◽  
Proximal Femur ◽  
Hip Fracture Risk ◽  
Dxa Scans ◽  
Femur Geometry
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