A possible connection between tumor necrosis factor alpha and adropin levels in polycystic ovary syndrome

2016 ◽  
Vol 39 (7) ◽  
pp. 747-754 ◽  
Author(s):  
T. Kume ◽  
M. Calan ◽  
O. Yilmaz ◽  
G. U. Kocabas ◽  
P. Yesil ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Polycystic Ovary Syndrome ◽  
Tumor Necrosis Factor Alpha ◽  
Tumor Necrosis ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Necrosis Factor

scholarly journals Role of osteocalcin, tumor necrosis factor-alpha and adiponectin in polycystic ovary syndrome patients with insulin resistance

2017 ◽  
Vol 14 (2) ◽  
pp. 89-93
Author(s):  
Gönül Erkan ◽  
Ahter Tanay Tayyar ◽  
Gökhan Açmaz ◽  
İptisam İpek Müderris ◽  
Gülden Başkol ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Tumor Necrosis Factor ◽  
Polycystic Ovary Syndrome ◽  
Tumor Necrosis ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Necrosis Factor

scholarly journals Endometrial Flushing Tumor Necrosis Factor Alpha and Interleukin 2 Levels in Women with Polycystic Ovary Syndrome, Leiomyoma and Endometrioma: Comparison with Healthy Controls

2019 ◽  
Vol 79 (05) ◽  
pp. 517-523
Author(s):  
Mustafa Demir ◽  
Senol Kalyoncu ◽  
Onur Ince ◽  
Bulent Ozkan ◽  
Sefa Kelekci ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Polycystic Ovary ◽  
Control Group ◽  
Healthy Controls ◽  
Ovary Syndrome ◽  
Necrosis Factor Alpha ◽  
Tnf Α ◽  
Factor Alpha ◽  
Necrosis Factor

Abstract Introduction An important open question in the literature is whether endometrial receptivity marker levels are different in infertility related diseases than healthy women. The aim of the study is to compare the levels of interleukin two (IL-2) and tumor necrosis factor alpha (TNF-α) during the implantation window in the endometrial flushing fluid of polycystic ovary syndrome (PCOS), endometrioma, leiomyoma patients with healthy controls. Material and Methods In this case control study, after obtaining endometrial flushing fluids at mid-luteal phase of ovulatory women with PCOS (n = 20), endometrioma (n = 19), leiomyoma (n = 20) and healthy controls (n = 20), IL-2 and TNF-α levels were measured using ELISA kits in BioTek ELISA devices. Results Mean TNF-α levels (ng/mL) were similar for the PCOS (305.6, p = 0.220) and the leiomyoma group (246.3, p = 0.502) compared to healthy patients (261.1). However, the levels were higher in the endometrioma group (338.2, p = 0,004) than the control group (261.1) in a statistically significant way. Mean IL-2 levels (ng/mL) were significantly lower in the PCOS (290.9, p = 0.0005), the leiomyoma (282.9, p = 0.0002) and the endometrioma patients (229.5, p = 0.0009) than the control group (416.0). Conclusion Relative to the control group, endometrial flushing fluid TNF-α levels were significantly higher in endometrioma patients and IL-2 levels were significantly lower in PCOS, leiomyoma and endometrioma patients. In benign gynecological diseases, endometrial markers related to infertility seem to show differences in endometrial flushing fluid. Future studies might identify the reference values for these markers, and endometrial markers can be used to diagnose gynecologic disorders causing infertility.

Elevated serum levels of tumor necrosis factor alpha in normal-weight women with polycystic ovary syndrome

Metabolism ◽  
1999 ◽  
Vol 48 (4) ◽  
pp. 437-441 ◽  
Author(s):  
Frank Gonzalez ◽  
Kuldip Thusu ◽  
Ehad Abdel-Rahman ◽  
Anu Prabhala ◽  
Madonna Tomani ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Polycystic Ovary ◽  
Elevated Serum ◽  
Serum Levels ◽  
Normal Weight ◽  
Ovary Syndrome ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Necrosis Factor
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