Comparing the Diagnostic Value of the Risk of Ovarian Malignancy Algorithm (ROMA) and Risk of Malignancy Index (RMI) in Women with an Adnexal Mass

2021 ◽  
Vol 19 (4) ◽  
Author(s):  
Zahra Honarvar ◽  
Mahdokht Monshi ◽  
Fatemeh Karami Robati
2016 ◽  
Vol 31 (5) ◽  
pp. 336-344 ◽  
Author(s):  
Khawla Al Musalhi ◽  
Manal Al Kindi ◽  
Faiza Al Aisary ◽  
Fatma Ramadhan ◽  
Thuraya Al Rawahi ◽  
...  

2020 ◽  
Vol 22 (4) ◽  
pp. 199-202
Author(s):  
Manisha Acharya ◽  
P Kumar ◽  
BB Shrestha ◽  
S Shrestha ◽  
R Amatya ◽  
...  

Adnexal mass is a common clinical finding in gynaecological practice. The study aims to find out the diagnostic value of clinical examination, ultrasonography and Ca-125 and its correlation, using Risk of Malignancy Index with histopathological diagnosis in adnexal masses. Clinical records were retrieved of women who had surgical management for adnexal mass in the last 2 years duration. Based on the data, Risk of Malignancy Index values were calculated. It was then compared with histopathological diagnosis. Out of 66 patients, 56 patients had benign tumor and 10 patients had malignancy. The Risk of Malignancy Index values of each patient was calculated which ranged from 8 to 2205 with mean value of 425.52 (SD±41.8). Risk of Malignancy Index sensitivity was 70%, specificity was 96.42%, positive predictive value was 77.78%, and negative predictive value was 95.83%. Risk of Malignancy Index is a reliable diagnostic tool in differentiating benign from malignant adnexal masses.


2016 ◽  
Vol 6 (2) ◽  
pp. 127
Author(s):  
Shamsun Nahar ◽  
Latifa Shamsuddin

<p><strong>Background:</strong> Screening programme for ovarian malignancy is an international public demand. <strong></strong></p><p><strong>Ojective:</strong> To validate a risk of malignancy index (RMI) incorporating serum CA125, abdominal ultrasound findings and menopausal status for preoperative diagnosis of ovarian malignancy among patient with adnexal mass.</p><p><strong>Methods:</strong> This prospective observa­tional study was conducted on 57 patients having adnexal mass admitted consecutively for surgical exploration in BSMMU from January 2000 to March 2001. S. CA125 assay &amp; abdominal ultrasonography was done within 10 days preoperatively. Ultrasound score (0, 1 &amp; 3) using 5 sonographic features &amp; menopausal score (1 &amp; 3) were calculated. RMI was detected by the formula "RMI = Ultrasound score - Menopausal score - S. CA125 level" Definitive diagnosis was based on histopathological examination.</p><p>See PDF for the rest of the abstract.</p>


2015 ◽  
Vol 25 (5) ◽  
pp. 809-814 ◽  
Author(s):  
Genevieve K. Lennox ◽  
Lua R. Eiriksson ◽  
Clare J. Reade ◽  
Felix Leung ◽  
Golnessa Mojtahedi ◽  
...  

2019 ◽  
pp. 1-4
Author(s):  
Sushma Rachel S

BACKGROUND: Ovarian cancer is the most common gynecological cancer associated with increased mortality. Early diagnosis is the important factor in improving the survival rate. OBJECTIVE: To evaluate and compare the performance of RMI, ROMAand R-OPS. METHODS: A validation study was conducted where 60 patients with adnexal mass who were planned to undergo surgery were included. Preoperatively, RMI and ROMAand R-OPS were calculated. The diagnostic performance of each was assessed and compared. RESULTS: 60% had benign mass, 10% had borderline neoplasia and 30% had malignant lesion. In the premenopausal group, RMI had a superior performance with a sensitivity of 75%. In postmenopausal group, R-OPS had a better performance followed by ROMA. CONCLUSION: As a diagnostic tool, an algorithm combining ultrasound imaging and both the serum markers CA125 and HE4 would be more accurate in prediction of malignancy in ovarian mass.


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