scholarly journals APPLICABILITY OF RISK OF MALIGNANCY INDEX IV FOR SCREENING MALIGNANT OVARIAN MASS AMONG PATIENT WITH ADNEXAL MASS AND ITS COMPARISION WITH OTHER RISK OF MALIGNANCY INDEXES

2018 ◽  
Vol 6 (10) ◽  
pp. 326-331
Author(s):  
Smrutishree Sahoo ◽  
◽  
Sujata Singh ◽  
Lucy Das ◽  
Sasmita Swain ◽  
...  
Keyword(s):  
Adnexal Mass ◽  
Ovarian Mass ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index

scholarly journals Evaluation of HE4, CA-125, Risk of Ovarian Malignancy Algorithm (ROMA) and Risk of Malignancy Index (RMI) in the Preoperative Assessment of Patients with Adnexal Mass

2016 ◽  
Vol 31 (5) ◽  
pp. 336-344 ◽  
Author(s):  
Khawla Al Musalhi ◽  
Manal Al Kindi ◽  
Faiza Al Aisary ◽  
Fatma Ramadhan ◽  
Thuraya Al Rawahi ◽  
...  
Keyword(s):  
Adnexal Mass ◽  
Preoperative Assessment ◽  
Ca 125 ◽  
Ovarian Malignancy ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index

Evaluation of Adnexal Masses-Correlation of Clinical, Sonological and Histological Findings in Adnexal Masses

2020 ◽  
Vol 22 (4) ◽  
pp. 199-202
Author(s):  
Manisha Acharya ◽  
P Kumar ◽  
BB Shrestha ◽  
S Shrestha ◽  
R Amatya ◽  
...  
Keyword(s):  
Predictive Value ◽  
Adnexal Mass ◽  
Diagnostic Value ◽  
Mean Value ◽  
Ca 125 ◽  
Histopathological Diagnosis ◽  
Adnexal Masses ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index ◽  
Clinical Records

Adnexal mass is a common clinical finding in gynaecological practice. The study aims to find out the diagnostic value of clinical examination, ultrasonography and Ca-125 and its correlation, using Risk of Malignancy Index with histopathological diagnosis in adnexal masses. Clinical records were retrieved of women who had surgical management for adnexal mass in the last 2 years duration. Based on the data, Risk of Malignancy Index values were calculated. It was then compared with histopathological diagnosis. Out of 66 patients, 56 patients had benign tumor and 10 patients had malignancy. The Risk of Malignancy Index values of each patient was calculated which ranged from 8 to 2205 with mean value of 425.52 (SD±41.8). Risk of Malignancy Index sensitivity was 70%, specificity was 96.42%, positive predictive value was 77.78%, and negative predictive value was 95.83%. Risk of Malignancy Index is a reliable diagnostic tool in differentiating benign from malignant adnexal masses.

scholarly journals A Case Report of Primary Ovarian Mucinous Adenocarcinoma treated at Dr. Akbar Niazi Teaching Hospital, Bara Kahu, Islamabad

2020 ◽  
Vol 24 (4) ◽  
pp. 430-433
Author(s):  
Jahan Ara Saeed
Keyword(s):  
Abdominal Distension ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Uneventful Recovery ◽  
Ovarian Mass ◽  
Resonance Imaging ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index ◽  
History Of ◽  
Stage 1

Introduction: This is a case of a patient who had a history of grossly increasing abdominal distension for 6 months. The patient had no symptoms except pressure symptoms with a regular menstrual cycle. She initially was investigated as a case of abdominal distension and indigestion. With increasing size, the discomfort was the main symptom. She attended our Gynaecology Outpatient department and was diagnosed as a case of Large Ovarian mass. The first investigation performed was Pelvic ultrasound and Tumour markers and a Risk of malignancy index were calculated. Her Magnetic resonance imaging with contrast showed a large well encapsulated ovarian mass with no ascites and no metastasis. After getting all the investigations and discussion with the patient a Staging Laparotomy with Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed, The ureters were stented before laparotomy to avoid damage to the ureters during surgery. She was diagnosed as Stage 1-A at the time of surgery and had an uneventful recovery. Her histopathology report showed a unilateral Mucinous cystadenocarcinoma with negative peritoneal wash and omentum histopathology.

COMPARISION OF RMI (RISK OF MALIGNANCY INDEX), ROMA (RISK OF OVARIAN MALIGNANCYALGORITHM) AND R-OPS (RAJAVITHI OVARIAN CANCER PREDICTION SCORE) ALGORITHMS IN PREDICTION OF OVARIAN MALIGNANCY IN ADNEXAL MASS

2019 ◽  
pp. 1-4
Author(s):  
Sushma Rachel S
Keyword(s):  
Ovarian Cancer ◽  
Adnexal Mass ◽  
Gynecological Cancer ◽  
Malignant Lesion ◽  
Serum Markers ◽  
Superior Performance ◽  
Cancer Prediction ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index ◽  
Benign Mass

BACKGROUND: Ovarian cancer is the most common gynecological cancer associated with increased mortality. Early diagnosis is the important factor in improving the survival rate. OBJECTIVE: To evaluate and compare the performance of RMI, ROMAand R-OPS. METHODS: A validation study was conducted where 60 patients with adnexal mass who were planned to undergo surgery were included. Preoperatively, RMI and ROMAand R-OPS were calculated. The diagnostic performance of each was assessed and compared. RESULTS: 60% had benign mass, 10% had borderline neoplasia and 30% had malignant lesion. In the premenopausal group, RMI had a superior performance with a sensitivity of 75%. In postmenopausal group, R-OPS had a better performance followed by ROMA. CONCLUSION: As a diagnostic tool, an algorithm combining ultrasound imaging and both the serum markers CA125 and HE4 would be more accurate in prediction of malignancy in ovarian mass.

The adnexal mass: benign or malignant? Evaluation of a risk of malignancy index

1993 ◽  
Vol 100 (10) ◽  
pp. 927-931 ◽  
Author(s):  
Ann Prys Davies ◽  
Ian Jacobs ◽  
Robert Woolas ◽  
Andrew Fish ◽  
David Oram
Keyword(s):  
Adnexal Mass ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index

scholarly journals The adnexal mass: Benign or malignant? Evaluation of risk of malignancy index

2016 ◽  
Vol 6 (2) ◽  
pp. 127
Author(s):  
Shamsun Nahar ◽  
Latifa Shamsuddin
Keyword(s):  
Adnexal Mass ◽  
Histopathological Examination ◽  
Menopausal Status ◽  
Abdominal Ultrasound ◽  
Ovarian Malignancy ◽  
Abdominal Ultrasonography ◽  
Serum Ca125 ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index ◽  
Ultrasound Score

<p><strong>Background:</strong> Screening programme for ovarian malignancy is an international public demand. <strong></strong></p><p><strong>Ojective:</strong> To validate a risk of malignancy index (RMI) incorporating serum CA125, abdominal ultrasound findings and menopausal status for preoperative diagnosis of ovarian malignancy among patient with adnexal mass.</p><p><strong>Methods:</strong> This prospective observa­tional study was conducted on 57 patients having adnexal mass admitted consecutively for surgical exploration in BSMMU from January 2000 to March 2001. S. CA125 assay &amp; abdominal ultrasonography was done within 10 days preoperatively. Ultrasound score (0, 1 &amp; 3) using 5 sonographic features &amp; menopausal score (1 &amp; 3) were calculated. RMI was detected by the formula "RMI = Ultrasound score - Menopausal score - S. CA125 level" Definitive diagnosis was based on histopathological examination.</p><p>See PDF for the rest of the abstract.</p>

scholarly journals Evaluation of Probably Benign Adnexal Masses in Postmenopausal Women

2017 ◽  
Vol 39 (05) ◽  
pp. 229-234
Author(s):  
Burcu Karakaya ◽  
Emre Ozgu ◽  
Hatice Kansu ◽  
Ozlem Evliyaoglu ◽  
Esma Sarikaya ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Adnexal Mass ◽  
Ca 125 ◽  
Benign Tumors ◽  
Adnexal Masses ◽  
Significant Difference ◽  
Risk Of Malignancy ◽  
Risk Of Malignancy Index ◽  
Index 2 ◽  
Malignancy Potential

Background Preoperatively identification of malignancy potential of a postmenopausal adnexal masses is important. Aim To evaluate the effectiveness of the Risk of Malignancy Index-2 in presumably benign adnexal masses in postmenopausal women. Study Design Retrospective, observational study. Methods 119 women with postmenopausal adnexal masses with a preliminary diagnosis of benign tumors according to the Risk of Malignancy Index-2 were included. Age, duration of menopause, ultrasonographic findings, and serum CA-125 levels were recorded preoperatively. The definitive diagnosis was based on postoperative histopathological examination. Results Of 119 adnexal mass, 10 were malignant and 109 were benign. There was no statistically significant difference with regard to age and tumor size between the groups. The two significant ultrasonographic parameter between groups were the presence of solid area in the mass and bilaterality. Moreover, if the cut off point for serum CA-125 was adjusted to 14.75 IU/mL according to ROC curve, a sensitivity value of 80% and a specificity value of 72% could be achieved to discriminate benign and malign cysts. Conclusion In the differential diagnosis of benign and malignant adnexal masses in postmenopausal women, the presence of a solid component, bilaterallity based on ultrasonography and high CA-125 values may be used as discriminative criteria. There is no direct relation between the size of the adnexal mass and malignancy potential. Therefore, in the malignancy indexes of postmenopausal women, we recommend lower cut-off values of CA-125 to increase the sensitivity of preoperative evaluation tests without having a great impact on negative predictive values.

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