History of Polymeric Gene Delivery Systems

2017 ◽  
Vol 375 (2) ◽  
Author(s):  
Peng Zhang ◽  
Ernst Wagner
Keyword(s):  
Gene Delivery ◽  
Delivery Systems ◽  
Polymeric Gene Delivery ◽  
History Of

Impact of the nature, size and chain topologies of carbohydrate–phosphorylcholine polymeric gene delivery systems

Biomaterials ◽  
2012 ◽  
Vol 33 (31) ◽  
pp. 7858-7870 ◽  
Author(s):  
Marya Ahmed ◽  
Manraj Jawanda ◽  
Kazuhiko Ishihara ◽  
Ravin Narain
Keyword(s):  
Gene Delivery ◽  
Delivery Systems ◽  
Polymeric Gene Delivery

Peptide-grafted dextran vectors for efficient and high-loading gene delivery

2019 ◽  
Vol 7 (4) ◽  
pp. 1543-1553 ◽  
Author(s):  
Yang Hu ◽  
Huifeng Wang ◽  
Haiqing Song ◽  
Megan Young ◽  
Yaqian Fan ◽  
...  
Keyword(s):  
Amino Acids ◽  
Gene Delivery ◽  
Building Blocks ◽  
Delivery Systems ◽  
High Loading ◽  
Structure And Properties ◽  
Unique Structure ◽  
Polymeric Gene Delivery

Among various polymeric gene delivery systems, peptide-based vectors demonstrate great potential owing to their unique structure and properties, including flexibility; however, there is insufficient molecular understanding of the role and properties of amino acids as building blocks in gene delivery.

Recent Progress in Polymeric Gene Delivery Systems

2003 ◽  
Vol 20 (4) ◽  
pp. 249-293 ◽  
Author(s):  
Khursheed Anwer ◽  
B. G. Rhee ◽  
Sanjeev Kumar Mendiratta
Keyword(s):  
Gene Delivery ◽  
Recent Progress ◽  
Delivery Systems ◽  
Polymeric Gene Delivery

Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release

2018 ◽  
Vol 18 (10) ◽  
pp. 857-880 ◽  
Author(s):  
Salma E. Ahmed ◽  
Nahid Awad ◽  
Vinod Paul ◽  
Hesham G. Moussa ◽  
Ghaleb A. Husseini
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Special Focus ◽  
Nano Drug Delivery ◽  
Medical Researchers ◽  
History Of ◽  
Overall Performance ◽  
Enhanced Stability

Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering anti-tumor agents with enhanced stability, durability and overall performance; especially when used along with targeting and triggering techniques. This work traces back the history of chemotherapy, addressing the main challenges that have encouraged the medical researchers to seek a sanctuary in nanotechnological-based drug delivery systems that are grafted with appropriate targeting techniques and drug release mechanisms. A special focus will be directed to acoustically triggered liposomes encapsulating doxorubicin.

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