Signal Intensity Ratio in Fluid Attenuation Inversion Recovery Sequences in Determining Cerebral Metastasis on Non-contrast-Enhanced Magnetic Resonance Imaging

2022 ◽  
Vol 4 (1) ◽  
Author(s):  
Dilek Sağlam ◽  
Hediye Pınar Günbey ◽  
Serap Yücel ◽  
Aslı Tanrıvermiş Sayıt ◽  
Kerim Aslan ◽  
...  
2011 ◽  
Vol 55 (3) ◽  
pp. 184-188 ◽  
Author(s):  
Ana R. Vlainich ◽  
João H. Romaldini ◽  
Ana B. Pedro ◽  
Chady S. Farah ◽  
Cicero A. Sinisgalli Jr.

OBJECTIVE: To compare ultrasonography (US) to magnetic resonance imaging (MRI) and the clinical activity score (CAS) in Graves' ophthalmopathy. SUBJECTS AND METHODS: Nineteen patients underwent extraocular muscle thickness measurements by US and MRI, reflectivity by US and signal-intensity ratio by MRI. There were also twelve US control subjects. RESULTS: US median thicknesses were greater than in controls. Correlation was found between US and MRI in the median thickness of the left eye rectus medial muscle as well as between signal-intensity ratio (SIR) and thickness by US. An inverse correlation was found between reflectivity and SIR in the inferior and lateral rectus. On associating the tests for detecting activity the best results were obtained with CAS plus MRI (sensitivity 75%), and US and MRI (positive predictive value 77% and specificity 80%). CONCLUSION: CAS and US results showed poor correlation with MRI results suggesting that they cannot replace each other but when combined these methods can improve the evaluation of thyroid-associated ophthalmopathy.


2020 ◽  
pp. 197140092098016
Author(s):  
Bernardo Corrêa de Almeida Teixeira ◽  
Felipe Constanzo ◽  
Patricia Sens ◽  
Ricardo Ramina ◽  
Dante Luiz Escuissato

Objectives Focal hyperintensity in the dorsal brainstem (HDB) has been described in large cerebellopontine angle tumours and is thought to represent vestibular nuclei degeneration, but its functional significance has not been thoroughly investigated. Our aim was to analyse its relationship to imaging characteristics of the tumour and inner-ear structures and to vestibulocochlear functional tests. Methods We retrospectively reviewed 54 patients with a histological diagnosis of vestibular schwannoma (VS). Magnetic resonance imaging tumour characteristics (size, cystic composition and distance from the cochlear aperture), signal intensity ratio of the cochlea and vestibule in fluid-attenuated inversion recovery (FLAIR) and fast imaging employing steady-state acquisition (FIESTA)/fast spin-echo imaging with variable flip angles (CUBE) and vestibulocochlear function tests (audiometry, auditory brainstem response (ABR) and video head impulse testing (vHIT)) were obtained. Statistical analyses were performed to evaluate their relation to focal HDB. Results Focal HDB was found in 22% of VS. It was significantly associated with large ( p < 0.001) and cystic ( p = 0.004) tumours and also with tumours located further from the cochlear aperture ( p = 0.039). The signal intensity ratio of the cochlea on FLAIR was higher in patients with HDB ( p < 0.014), but this difference was not observed in FIESTA/CUBE ( p = 0.981). Audiometry, ABR and vHIT results did not significantly differ in patients with HDB, but ABR results were worse in patients with higher cochlear signal intensity on FLAIR sequences ( p = 0.026). Conclusions Focal HDB in patients with VS was associated with increased signal intensity ratio of the cochlea on FLAIR in patients with VS but not directly to the results of vestibulocochlear function tests.


2010 ◽  
Vol 13 (3) ◽  
pp. 319-323 ◽  
Author(s):  
Lin-Feng Wang ◽  
Ying-Ze Zhang ◽  
Yong Shen ◽  
Yan-Ling Su ◽  
Jia-Xin Xu ◽  
...  

ObjectThe aim of this study was to investigate the clinical significance of both the signal intensity ratio obtained from MR imaging and clinical manifestations on the prognosis of patients with cervical ossification of the posterior longitudinal ligament.MethodsThe authors retrospectively reviewed the records of 58 patients with cervical ossification of the posterior longitudinal ligament who underwent cervical laminoplasty from February 1999 to July 2007. Magnetic resonance imaging (1.5-T) was performed in all patients before surgery. Sagittal T2-weighted images of the cervical spinal cord compressed by the ossified posterior longitudinal ligament showed increased intramedullary signal intensity, whereas the sagittal images obtained at the C7–T1 disc levels were of normal intensity. The signal intensity ratio between regions of intramedullary increased signal intensity and the normal C7–T1 disc level was calculated based on the signal intensity values generated from the MR imaging workstation. Patients were divided into 3 groups according to their signal intensity ratio (high, intermediate, and low signal intensity groups).ResultsThere were significant differences between the 3 groups regarding recovery rate (p < 0.001), age (p = 0.022), duration of disease (p = 0.001), Babinski sign (p < 0.001), ankle clonus (p < 0.001), and both pre- and postoperative Japanese Orthopaedic Association score (p < 0.001). There was no significant difference in sex among the 3 groups (p = 0.391).ConclusionsPatients with low signal intensity ratios that changed on T2-weighted imaging experienced a good surgical outcome. Low increased signal intensity might reflect mild neuropathological alteration in the spinal cord and greater recuperative potential. An increased signal intensity ratio with positive pyramidal signs indicates less recuperative potential of the spinal cord and a poor surgical outcome.


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