scholarly journals Just the facts: testing patients with suspected pulmonary embolism

CJEM ◽  
2022 ◽  
Author(s):  
Kerstin de Wit ◽  
Oksana Motalo ◽  
Shreyash Dalmia
Keyword(s):  
Pulmonary Embolism ◽  
Suspected Pulmonary Embolism

A Comparative Analysis of D-Dimer Assays in Patients with Clinically Suspected Pulmonary Embolism

1993 ◽  
Vol 70 (03) ◽  
pp. 408-413 ◽  
Author(s):  
Edwin J R van Beek ◽  
Bram van den Ende ◽  
René J Berckmans ◽  
Yvonne T van der Heide ◽  
Dees P M Brandjes ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Comparative Analysis ◽  
High Probability ◽  
Pulmonary Emboli ◽  
Plasma Samples ◽  
Suspected Pulmonary Embolism ◽  
Lung Scan ◽  
D Dimer

SummaryTo avoid angiography in patients with clinically suspected pulmonary embolism and non-diagnostic lung scan results, the use of D-dimer has been advocated. We assessed plasma samples of 151 consecutive patients with clinically suspected pulmonary embolism. Lung scan results were: normal (43), high probability (48) and non-diagnostic (60; angiography performed in 43; 12 pulmonary emboli). Reproducibility, cut-off values, specificity, and percentage of patients in whom angiography could be avoided (with sensitivity 100%) were determined for two latex and four ELISA assays.The latex methods (cut-off 500 μg/1) agreed with corresponding ELISA tests in 83% (15% normal latex, abnormal ELISA) and 81% (7% normal latex, abnormal ELISA). ELISA methods showed considerable within- (2–17%) and between-assay Variation (12–26%). Cut-off values were 25 μg/l (Behring), 50 μg/l (Agen), 300 μg/l (Stago) and 550 μg/l (Organon). Specificity was 14–38%; in 4–15% of patients angiography could be avoided.We conclude that latex D-dimer assays appear not useful, whereas ELISA methods may be of limited value in the exclusion of pulmonary embolism.

scholarly journals Challenges in the diagnostic approach of suspected pulmonary embolism in COVID-19 patients

2021 ◽  
Author(s):  
Milou Anne Maria Stals ◽  
Fleur Kaptein ◽  
Lucia Kroft ◽  
FA Klok ◽  
Menno V Huisman
Keyword(s):  
Pulmonary Embolism ◽  
Diagnostic Approach ◽  
Suspected Pulmonary Embolism

Overutilisation of CTPA for suspected pulmonary embolism

2019 ◽  
Vol 74 ◽  
pp. e30-e31
Author(s):  
S.J. Connor ◽  
M. Gupta ◽  
S. Kearney ◽  
T. Chooi Oh
Keyword(s):  
Pulmonary Embolism ◽  
Suspected Pulmonary Embolism

Accuracy of X-ray with perfusion scan in young patients with suspected pulmonary embolism

2015 ◽  
Vol 136 (2) ◽  
pp. 221-224 ◽  
Author(s):  
J. van Es ◽  
R.A. Douma ◽  
R.E.L. Hezemans ◽  
A. Penaloza ◽  
S. Motte ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Young Patients ◽  
Suspected Pulmonary Embolism ◽  
X Ray ◽  
Perfusion Scan
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