Effect of intraperitoneal administration of oxygen on the course of experimentally induced peritonitis

— In this study we have investigated the effects of melanocortins (group analogs of neuropeptides) on the psychoemotional state of rats under conditions of experimental social stress. The study was carried out on male rats which were injected intraperitoneally for 20 days with the neuropeptide drugs Semax and ACTH(6-9)-ProGly-Pro at a dose of 100 μg/kg/day starting from the 1st day of stress exposure. The psychoemotional state of the animals was evaluated by means of the behavioral test of elevated cruciform maze. It was found that intraperitoneal administration of neuropeptides (Semax, ACTH(6-9)- Pro-Gly-Pro) helps to reduce high anxiety levels in animals both with aggressive and submissive types of behavior under conditions of experimental social stress via their psychomodulatory effects.

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Experimentally induced mesothelioma in white rats in response to intraperitoneal administration of amorphous crocidolite asbestos: Preliminary report

Environmental Research ◽

10.1016/0013-9351(82)90013-5 ◽

1982 ◽

Vol 29 (1) ◽

pp. 123-133 ◽

Cited By ~ 11

Author(s):

K. Kolev

Keyword(s):

Preliminary Report ◽

Intraperitoneal Administration ◽

White Rats ◽

Experimentally Induced

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Influence of C60FAS on the speed-power parameters of the tetanic contraction of muscle soleus on the conditions of experimentally-induced ischemia at different durations in alcoholised rats

Bulletin of Taras Shevchenko National University of Kyiv Series Problems of Physiological Functions Regulation ◽

10.17721/2616_6410.2017.23.59-65 ◽

2017 ◽

Vol 23 (2) ◽

pp. 59-69

Author(s):

S. Zay ◽

O. Motuzyuk ◽

V. Belobrov ◽

D. Vulitska ◽

O. Nozdrenko

Keyword(s):

Synergistic Effect ◽

Intraperitoneal Administration ◽

Ischemic Injury ◽

Tetanic Contraction ◽

Chronic Alcoholic ◽

Alcoholic Intoxication ◽

Experimentally Induced

In the article presented the results of tenzometric studies of the effect of C60FAS (concentration 0.15 mg / ml) at a dose of 1 mg / kg ON the speed-power parameters of the tetanic reduction of muscle soleus under conditions of ischemia in chronic alcoholic rats during 1-hour and 2-hour. The synergistic effect of ischemic injury and alcoholic intoxication, as compared to the native muscle, is manifested in reducing the reduction power to 26,25 ± 3,23 and 20,2 ± 2,45 (p≤0,01), and an increase in the time to achieve it the maximum values for 1.33 ± 0.12s and 1.45 ± 0.15s (p≤0.01) respectively. It is shown that if the intraperitoneal administration of the VRC60 solution is given, these indices are likely to increase.

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Experimental Amyloidosis Induced by Immune Complex

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100066978 ◽

1971 ◽

Vol 29 ◽

pp. 582-583

Author(s):

A. Kawaoi

Keyword(s):

Immune Complex ◽

Systemic Amyloidosis ◽

Human Diseases ◽

Experimental Amyloidosis ◽

Freund’S Complete Adjuvant ◽

Freund's Complete Adjuvant ◽

Immunological Approach ◽

Experimentally Induced

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.

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Effects of Experimentally Induced Pain on Mismatch Negativity

Journal of Psychophysiology ◽

10.1027/0269-8803.20.1.21 ◽

2006 ◽

Vol 20 (1) ◽

pp. 21-31 ◽

Cited By ~ 6

Author(s):

Bruce D. Dick ◽

John F. Connolly ◽

Michael E. Houlihan ◽

Patrick J. McGrath ◽

G. Allen Finley ◽

...

Keyword(s):

Cognitive Processing ◽

Mismatch Negativity ◽

Event Related Potentials ◽

Disruptive Effect ◽

Ischemic Pain ◽

Active Attention ◽

Early Processing ◽

Related Potentials ◽

Healthy Participants ◽

Experimentally Induced

Abstract: Previous research has found that pain can exert a disruptive effect on cognitive processing. This experiment was conducted to extend previous research with participants with chronic pain. This report examines pain's effects on early processing of auditory stimulus differences using the Mismatch Negativity (MMN) in healthy participants while they experienced experimentally induced pain. Event-related potentials (ERPs) were recorded using target and standard tones whose pitch differences were easy- or difficult-to-detect in conditions where participants attended to (active attention) or ignored (passive attention) the stimuli. Both attention manipulations were conducted in no pain and pain conditions. Experimentally induced ischemic pain did not disrupt the MMN. However, MMN amplitudes were larger to difficult-to-detect deviant tones during painful stimulation when they were attended than when they were ignored. Also, MMN amplitudes were larger to the difficult- than to the easy-to-detect tones in the active attention condition regardless of pain condition. It appears that rather than exerting a disruptive effect, the presence of experimentally induced pain enhanced early processing of small stimulus differences in these healthy participants.

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