Application of the median method to the determination of kinetic constants for competitive enzyme inhibition

The effects of errors in Km and Vmax. on the determination of the kinetic constants for the irreversible inhibition of acetylcholinesterase were determined. The results show that small errors in the values of Km and Vmax. give rise to large errors in the fitted parameters k2 and Kd. The problem may be minimized for multiple progress curves by selecting an appropriate number and distribution of inhibitor concentrations.

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KINETIC CONSTANTS DETERMINATION OF PETROLEUM REFINERY EFFLUENT TREATMENT IN A UASB REACTOR USING RSM

Environmental Engineering and Management Journal ◽

10.30638/eemj.2017.014 ◽

2017 ◽

Vol 16 (1) ◽

pp. 121-130 ◽

Cited By ~ 1

Author(s):

Seyyed Mohammad Mousavi ◽

Seyed Omid Rastegar ◽

Seyed Abbas Shojaosadati ◽

Soheila Sheibani

Keyword(s):

Petroleum Refinery ◽

Kinetic Constants ◽

Effluent Treatment ◽

Uasb Reactor ◽

Refinery Effluent ◽

Petroleum Refinery Effluent

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Simulation of extracellular nucleotide hydrolysis and determination of kinetic constants for the ectonucleotidases.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)66741-9 ◽

1986 ◽

Vol 261 (33) ◽

pp. 15505-15507

Author(s):

L L Slakey ◽

K Cosimini ◽

J P Earls ◽

C Thomas ◽

E L Gordon

Keyword(s):

Kinetic Constants ◽

Extracellular Nucleotide ◽

Nucleotide Hydrolysis

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Determination of the Kinetic Constants of a Chemical Reaction in Heterogeneous Phase Using Parameterized Metaheuristics

Procedia Computer Science ◽

10.1016/j.procs.2013.05.243 ◽

2013 ◽

Vol 18 ◽

pp. 787-796 ◽

Cited By ~ 6

Author(s):

José-Matías Cutillas-Lozano ◽

Domingo Giménez

Keyword(s):

Chemical Reaction ◽

Kinetic Constants ◽

Heterogeneous Phase

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Experimental determination of intrinsic denitrification kinetic constants

Biotechnology and Bioengineering ◽

10.1002/bit.260231020 ◽

1981 ◽

Vol 23 (10) ◽

pp. 2403-2406 ◽

Cited By ~ 13

Author(s):

Led T. Mulcahy ◽

Wen K. Shieh ◽

Enrique J. LaMotta

Keyword(s):

Experimental Determination ◽

Kinetic Constants

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Enzymatic methanolysis reaction of canola oil using capillary channel reactor: Determination of the kinetic constants-involved

Journal of Molecular Catalysis B Enzymatic ◽

10.1016/j.molcatb.2016.06.014 ◽

2016 ◽

Vol 132 ◽

pp. 47-53 ◽

Cited By ~ 9

Author(s):

Alireza Habibi ◽

Sepideh Fahim ◽

Nooshin Shirvani ◽

Masoud Rahimi

Keyword(s):

Canola Oil ◽

Kinetic Constants ◽

Channel Reactor ◽

Capillary Channel

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CATIONIC COPOLYMERIZATION OF ISOBUTYLENE WITH ISOPRENE: KINETICS OF THE PROCESS AND DETERMINATION OF KINETIC CONSTANTS

Rubber Chemistry and Technology ◽

10.5254/rct.15.84889 ◽

2015 ◽

Vol 88 (4) ◽

pp. 574-583 ◽

Cited By ~ 4

Author(s):

N. V. Ulitin ◽

K. A. Tereshchenco ◽

D. A. Shiyan ◽

G. E. Zaikov

Keyword(s):

Experimental Data ◽

Molecular Weight ◽

Cationic Polymerization ◽

Methyl Chloride ◽

Theoretical Description ◽

Kinetic Constants ◽

Molecular Weight Characteristics ◽

Cationic Copolymerization ◽

Kinetics Of

ABSTRACT A theoretical description has been developed of the kinetics of isobutylene with isoprene (IIR) cationic polymerization in the environment of methyl chloride on aluminum trichloride as the catalyst. Based on experimental data on the kinetics of copolymerization (isobutylene conversion curve) and the molecular weight characteristics of the copolymer of IIR, kinetic constants for the process were found. Adequacy of the developed theoretical description of the kinetics of the IIR copolymerization process was confirmed by comparing the experimental molecular-weight characteristics calculated by this description, independent characteristics, and IIR unsaturation.

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