Inhibition, post-hydroxymethylglutaryl-CoA regulation and relation to cell growth of cholesterol biosynthesis in cultured human skin fibroblasts

Author(s):  
Christiane Tabacik ◽  
Sigrid Aliau ◽  
Charles Sultan
1987 ◽  
Vol 36 (12) ◽  
pp. 1901-1906 ◽  
Author(s):  
Alberto Corsini ◽  
Franco Bernini ◽  
Giuliana Cighetti ◽  
Maurizio Soma ◽  
Giovanni Galli ◽  
...  

1986 ◽  
Vol 19 (1) ◽  
pp. 39-47 ◽  
Author(s):  
G. L. Whitson ◽  
W. L. Carrier ◽  
Andrew A. Francis ◽  
C. C. Shih ◽  
S. Georghiou ◽  
...  

Author(s):  
Agnieszka Galanty ◽  
Marta Michalik ◽  
Łukasz Sędek ◽  
Irma Podolak

AbstractWe investigated the effect of a triterpene saponoside from Lysimachia thyrsiflora L. upon the viability, proliferation, morphology and cell motility of human melanoma HTB-140 cells and human skin fibroblasts (HSFs). The compound, denoted LTS-4, decreased the viability and rate of cell growth of both cell types in a time-and dose-dependent manner, and proved cytotoxic against cancer cells at significantly lower concentrations than for fibroblasts. LTS-4 also affected the morphology of the examined cells, causing vacuolisation and actin cytoskeleton disintegration, and had an inhibitory effect on the tumour cell motility.


1999 ◽  
Vol 33 (3) ◽  
pp. 267-276
Author(s):  
Munehiro Iketani ◽  
Yukiko Matsunaga ◽  
Toshio Nishiyama ◽  
Minoru Fukuda ◽  
Tasuku Takamatsu

1988 ◽  
Vol 173 (2) ◽  
pp. 261-267 ◽  
Author(s):  
Ryu-ichiro HATA ◽  
Hironobu SUNADA ◽  
Katsuhiko ARAI ◽  
Toshiaki SATO ◽  
Yoshifumi NINOMIYA ◽  
...  

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