Skunks have gene sequences in their cellular DNA related to squirrel monkey retrovirus: Transmission between species of a New World primate endogenous type D retrovirus

DNA samples from a variety of New World monkeys were screened by using a broad-spectrum PCR targeting the VP1 gene of polyomaviruses. This resulted in the characterization of the first polyomavirus from a New World primate. This virus naturally infects squirrel monkeys (Saimiri sp.) and is provisionally named squirrel monkey polyomavirus (SquiPyV). The complete genome of SquiPyV is 5075 bp in length, and encodes the small T and large T antigens and the three structural proteins VP1, VP2 and VP3. Interestingly, the late region also encodes a putative agnoprotein, a feature that it shares with other polyomaviruses from humans, baboons and African green monkeys. Comparison with other polyomaviruses revealed limited sequence similarity to any other polyomavirus, and phylogenetic analysis of the VP1 gene confirmed its uniqueness.

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Endogenous New World primate retrovirus: interspecies antigenic determinants shared with the major structural protein of type-D RNA viruses of Old World monkeys.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.74.12.5734 ◽

1977 ◽

Vol 74 (12) ◽

pp. 5734-5738 ◽

Cited By ~ 6

Author(s):

S. Hino ◽

S. R. Tronick ◽

R. L. Heberling ◽

S. S. Kalter ◽

A. Hellman ◽

...

Keyword(s):

New World ◽

Rna Viruses ◽

Antigenic Determinants ◽

Old World Monkeys ◽

Structural Protein ◽

Old World ◽

Major Structural Protein ◽

World Primate ◽

Type D

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The Squirrel Monkey: Characterization of a New-World Primate Model of Experimental Choroidal Neovascularization and Comparison with the Macaque

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.03-0718 ◽

2004 ◽

Vol 45 (2) ◽

pp. 625 ◽

Cited By ~ 9

Author(s):

Mark H. Criswell ◽

Thomas A. Ciulla ◽

Tiffany E. Hill ◽

Ward Small ◽

Ronald P. Danis ◽

...

Keyword(s):

Squirrel Monkey ◽

Choroidal Neovascularization ◽

New World ◽

Primate Model ◽

World Primate

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The common marmoset: A new world primate species with limited Mhc class II variability

Immunology Letters ◽

10.1016/s0165-2478(97)86858-7 ◽

1997 ◽

Vol 56 (1-3) ◽

pp. 5

Author(s):

S Antunes

Keyword(s):

Mhc Class Ii ◽

New World ◽

Common Marmoset ◽

Class Ii ◽

Primate Species ◽

World Primate ◽

The Common

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THE STRUCTURE AND BIOSYNTHESIS OF HEMOGLOBINS A AND A2IN THE NEW WORLD PRIMATE Ateles PANISCUS: A PRELIMINARY ACCOUNT

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1969.tb27806.x ◽

1969 ◽

Vol 165 (1 Second Confer) ◽

pp. 360-377 ◽

Cited By ~ 9

Author(s):

S. H. Boyer ◽

E. F. Crosby ◽

G. L. Fuller ◽

A. N. Noyes ◽

J. G. Adams

Keyword(s):

New World ◽

World Primate ◽

Ateles Paniscus ◽

Preliminary Account

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Enzootic Toxoplasmosis in Caged Squirrel Monkeys Saimiri sciureus

Pathologia veterinaria ◽

10.1177/030098586800500604 ◽

1968 ◽

Vol 5 (6) ◽

pp. 538-560 ◽

Cited By ~ 5

Author(s):

G. E. McKissick ◽

H. L. Ratcliffe ◽

A. Koestner

Keyword(s):

Trypanosoma Cruzi ◽

Protective Immunity ◽

New World ◽

Squirrel Monkeys ◽

Saimiri Sciureus ◽

Local Concentration ◽

World Primate ◽

History Of ◽

The Individual

An enzootic of toxoplasmosis occurred in caged squirrel monkeys ( Saimiri sciureus, a New World primate) which resulted in 9 deaths during an interval of 22 months. Diagnosis was based on morphology of the organism, character and distribution of the lesions, and laboratory history of the monkeys. The character of the lesions was essentially necrotic. The chronological incidence of the disease and distribution of lesions and organisms are tabulated. Trypanosoma cruzi which causes Chaga's disease is differentiated morphologically from toxoplasma. Incidence and lesions of the enzootic suggest 5 factors to be considered in the pathogenesis of toxoplasmosis in squirrel monkeys. They are: (1) lack of protective immunity, (2) local concentration of toxin and/or catabolites of reproduction of the organism, (3) individual tissue susceptibility to the organism, (4) capillary thrombosis, and (5) ability of the individual to adapt to its environment.

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